FB2026_02 , released June 18, 2026
Allele: Dmel\nanos538.αTub84B.UTR.Tag:HA
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General Information
Symbol
Dmel\nanos538.αTub84B.UTR.Tag:HA
Species
D. melanogaster
Name
FlyBase ID
FBal0102468
Feature type
allele
Associated gene
Dmel\nanos
Associated Insertion(s)
Carried in Construct
P{nanos-tub3'UTR.538}
Key Links
Transgenic product class
missense_variant
(Arrizabalaga and Lehmann, 1999)
Mutagen
Nature of the Allele
Transgenic product class
missense_variant
(Arrizabalaga and Lehmann, 1999)
Mutagen
ethyl methanesulfonate
(Arrizabalaga and Lehmann, 1999)
Progenitor genotype
Carried in construct
P{nanos-tub3'UTR.538}
Cytology
Description

Genomic nanos fragment in which the nanos 3'UTR has been replaced with the αTub84B 3'UTR. The coding sequence contains a V354M amino acid substitution (the numbering is as given for the genomic sequence of nanos in FBrf0053387, with one correction: an extra three bases (AGA) have been found between bases 1410 and 1411, replacing His 201 with Gln and Ile). A Tag:HA epitope has been inserted at the 5' end of the nanos coding region.

(Arrizabalaga and Lehmann, 1999)
Allele components
Component
Use(s)
Regulatory region(s)
αTub84B
Encoded product / tool
nanos
Tagged with
Tag:HA
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Fails to rescue

      nanos538.αTub84B.UTR.Tag:HA fails to rescue nanos18/Df(3R)Delta-X43

      (Arrizabalaga and Lehmann, 1999)

      nanos538.αTub84B.UTR.Tag:HA fails to rescue nanos18

      (Arrizabalaga and Lehmann, 1999)
      Comments

      Fails to rescue the abdominal phenotype of embryos derived from nos18 females. Fails to rescue the oogenesis defects of embryos derived from nos18/Df(3R)Dl-X43 females.

      (Arrizabalaga and Lehmann, 1999)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (4)
      Reported As
      Symbol Synonym
      nanos538.αTub84B.UTR.Tag:HA
      nos538.αTub84B.UTR.T:Ivir\HA1
      nos538.αTub84B.UTR.Tag:HA
      nos538
      (Arrizabalaga and Lehmann, 1999)
      Name Synonyms
      Secondary FlyBase IDs
        References (1)