FlyBase Allele Report: Dmel\eRF1[K3]

General Information

Symbol

Dmel\eRF1^K3

Species

D. melanogaster

Name

FlyBase ID

FBal0102525

Feature type

allele

Associated gene

Dmel\eRF1

Associated Insertion(s)

Carried in Construct

Key Links

Genomic Maps

JBrowse

Allele class

Mutagen

ethyl methanesulfonate

Nature of the Allele

Allele class

Mutagen

ethyl methanesulfonate

(Lukinova et al., 1999)

Progenitor genotype

Cytology

Description

Amino acid replacement: W15term.

(Chao et al., 2003)

Nucleotide substitution: G?A.

(Chao et al., 2003)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

point_mutation

3L:20,349,164..20,349,164 [+]

Nucleotide change:

G20349164A

Reported nucleotide change:

G?A

Amino acid change:

Reported amino acid change:

W15term

Comment:

G to A nucleotide change at the second or third position of the Trp codon leads to a nonsense mutation (exact site of mutation unspecified).

(Chao et al., 2003)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal | recessive

(Chao et al., 2003, Lukinova et al., 1999)

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Suppressor of

Statement

Reference

eRF1^K3 is a suppressor of phenotype of wg^PE4

(Chao et al., 2003)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Fails to complement

eRF1^KY7

(Chao et al., 2003)

eRF1^A7

(Chao et al., 2003)

eRF1^C1

(Chao et al., 2003)

eRF1^C2

(Chao et al., 2003)

eRF1^F2

(Chao et al., 2003)

eRF1^K7

(Chao et al., 2003)

eRF1^U3

(Chao et al., 2003)

eRF1^V2

(Chao et al., 2003)

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (4)

Reported As

Symbol Synonym

(Lukinova et al., 1999)

eRF1^K3

l(3)77ABb^K3

l(3)neo28^K3

Name Synonyms

Secondary FlyBase IDs

References (2)

Report Sections

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