FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Spn77BaW7
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General Information
Symbol
Dmel\Spn77BaW7
Species
D. melanogaster
Name
FlyBase ID
FBal0102574
Feature type
allele
Associated gene
Dmel\Spn77Ba
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Lukinova et al., 1999)
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      81% of flies expressing Spn77BadsRNA.WIZ.Scer\UAS under the control of Scer\GAL4btl.PS are viable at 18[o]C, whereas all animals die before the adult stage if the animals also carry Spn77BaW7/+.

      (Tang et al., 2008)

      Hemizygotes show early lethality.

      (Lukinova et al., 1999)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescued by

      Spn77BaW7 is rescued by Spn77BaUASp.Tag:HA/Scer\GAL4Act.PU

      (Tang et al., 2008)
      Comments

      Expression of Spn77BaScer\UAS.P\T.T:Ivir\HA1 under the control of Scer\GAL4hs.PB at 18[o]C allows some Spn77BaW7 animals to grow to the second instar stage. These animals have melanised trachea and in most cases die before reaching the third instar stage.

      Expression of Spn77BaScer\UAS.P\T.T:Ivir\HA1 under the control of Scer\GAL4hs.PB at 22-25[o]C allows some Spn77BaW7 animals to survive to the third larval instar or pupal stages. These larvae and pupae have melanised trachea.

      (Tang et al., 2008)
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      Spn77BaW7
      W7
      (Lukinova et al., 1999)
      l(3)77ABiW7
      (Tang et al., 2008)
      Name Synonyms
      Secondary FlyBase IDs
        References (2)