FlyBase Allele Report: Dmel\hth[UAS.Tag:MYC]

General Information

Symbol

Dmel\hth^UAS.Tag:MYC

Species

D. melanogaster

Name

FlyBase ID

FBal0102682

Feature type

allele

Associated gene

Dmel\hth

Associated Insertion(s)

Carried in Construct

P{UAS-MYC-HTH}

Key Links

Transgenic product class

wild_type

(Ryoo et al., 1999)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

wild_type

(Ryoo et al., 1999)

Mutagen

in vitro construct

(Ryoo et al., 1999)

Progenitor genotype

Carried in construct

P{UAS-MYC-HTH}

Cytology

Description

UASt regulatory sequences drive expression of the complete hth protein tagged with Tag:MYC.

(Ryoo et al., 1999)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

hth

Tagged with

Tag:MYC

epitope tag

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

visible | homeotic | male, with Scer\GAL4^pnr-MD237

(Ryoo et al., 1999)

Phenotype Manifest In

abdominal tergite 5 & trichome | male, with Scer\GAL4^pnr-MD237

(Ryoo et al., 1999)

abdominal tergite 5 | male, with Scer\GAL4^pnr-MD237

(Ryoo et al., 1999)

abdominal tergite 6 & trichome | male, with Scer\GAL4^pnr-MD237

(Ryoo et al., 1999)

abdominal tergite 6 | male, with Scer\GAL4^pnr-MD237

(Ryoo et al., 1999)

dorsal margin photoreceptor cell | ectopic, with Scer\GAL4^GMR.long

(Wernet et al., 2003)

photoreceptor cell R7, with Scer\GAL4^GMR.long

(Wernet et al., 2003)

photoreceptor cell R8, with Scer\GAL4^GMR.long

(Wernet et al., 2003)

Detailed Description

Statement

Reference

Expression of hth^{Scer\UAS.T:Hsap\MYC} in all photoreceptor neurons under the control of Scer\GAL4^GMR.PF induces dual terminals in the medial M6 medulla.

(Chin et al., 2014)

Expression of hth^{Scer\UAS.T:Hsap\MYC} under the control of Scer\GAL4^GMR.long results in all inner photoreceptors having rhabdomeres with an increased diameter, as occurs in the dorsal rim area (DRA) of the eye in wild-type flies. Some of these rhabdomeres have defects in morphology, having a kidney-like shape or being split into two.

(Wernet et al., 2003)

Expression of hth^{Scer\UAS.T:Hsap\MYC} under the control of Scer\GAL4^pnr-MD237 results in a transformation of tergites 5 and 6 into a more anterior, lightly pigmented identity in males. The density of trichomes in these tergites is increased.

(Ryoo et al., 1999)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

hth^{Scer\UAS.T:Hsap\MYC}

hth^UAS.Tag:MYC

Name Synonyms

Secondary FlyBase IDs

References (3)

Report Sections

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