When driven by Scer\GAL4^GMR.PF, W^Scer\UAS.cCa flies display little or no adult eye tissue. When somatic clones are induced in the follicle cells (driven by Scer\GAL4^Act5C.PP), occasional cells display nuclear condensation 12-18hrs post induction. By 24-30 hours the frequency of cell death is much higher. Older, larger clones display many aberrant nuclei and degenerating follicle cells can be observed at all oogenic stages leading to discontinuities in the follicle layer. This can be observed in mosaic egg chambers from about stage 6, but not in earlier previtellogenic chambers. 24-30 hours post induction, a phenotype is also seen in nurse cells - in every ovary a variable number of egg chambers at stages 7-8 or later displayed degenerating nurse cells. This phenotype is always associated with degenerating follicle cells, and not seen in younger clones (before stage 7), even in the presence of large follicle cell clones. When somatic clones are induced in the follicle cells (driven by Scer\GAL4^Act5C.PP), examination by TUNEL analysis suggest that nuclei within the cones have a DNA fragmentation phenotype and are being induced to apoptosis.

Scer\GAL4^GMR.PF, hid^UAS.cCa has eye phenotype, suppressible by BacA\p35^UAS.cCa, Scer\GAL4^GMR.PF