FB2026_02 , released June 18, 2026
Allele: Dmel\effRK1859
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General Information
Symbol
Dmel\effRK1859
Species
D. melanogaster
Name
FlyBase ID
FBal0103844
Feature type
allele
Associated gene
Dmel\eff
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Cytology
    Description
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In

        egg chamber & cell

        (Lilly et al., 2000)

        egg chamber & mitotic cell cycle

        (Lilly et al., 2000)

        nurse cell fusome

        (Lilly et al., 2000)
        Detailed Description
        Statement
        Reference

        About 22% of egg chambers from eff8/effRK1859 females contain 32-cell cysts. Large fusomes with an increased number of branches relative to wild-type are also seen.

        (Lilly et al., 2000)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Phenotype Manifest In
        Suppressed by
        Statement
        Reference

        effRK1859 has egg chamber phenotype, suppressible by CycA[+]/CycA01545

        (Lilly et al., 2000)

        effRK1859 has egg chamber phenotype, suppressible by Df(2R)59AB

        (Lilly et al., 2000)
        NOT suppressed by
        Statement
        Reference

        effRK1859 has egg chamber phenotype, non-suppressible by Df(2L)r10

        (Lilly et al., 2000)
        Additional Comments
        Genetic Interactions
        Statement
        Reference

        The 32 cell cyst phenotype is suppressible by adding heterozygous CycA01545, reducing the proportion of abnormal cysts seen to less than 6%. The addition of Df(2R)59AB also suppresses the phenotype, lowering the number of abnormal cysts seen by threefold. Df(2L)r10 however has no discernible effect on this phenotype.

        (Lilly et al., 2000)
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (0)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (1)
        Reported As
        Symbol Synonym
        effRK1859
        Name Synonyms
        Secondary FlyBase IDs
          References (1)