FlyBase Allele Report: Dmel\upd1[sisC-1]

General Information

Symbol

Dmel\upd1^sisC-1

Species

D. melanogaster

Name

FlyBase ID

FBal0104466

Feature type

allele

Associated gene

Dmel\upd1

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

Mutagen

Nature of the Allele

Allele class

Mutagen

Progenitor genotype

Cytology

Description

1.6kb DNA insertion and an approximately 100bp duplication near the 5' end of the upd1 gene.

(Sefton et al., 2000)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

viable

(Sefton et al., 2000)

Phenotype Manifest In

Detailed Description

Statement

Reference

upd1^sisC-1 has no mutant phenotype by itself, even when hemizygous over a deficiency for upd1.

(Sefton et al., 2000)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Other

Statement

Reference

Bap60¹, sisA[+]/sisA¹, upd1^sisC-1/os[+] has partially lethal - majority die | dominant | maternal effect | female limited phenotype

(Möller et al., 2005)

sisA¹, upd1^sisC-5/upd1^sisC-1 has lethal | dominant phenotype

(Sefton et al., 2000)

sisA¹, upd1^sisC-5/upd1^sisC-1, upd1^t4.8 has lethal phenotype

(Sefton et al., 2000)

sisA¹, upd1^sisC-5/upd1^sisC-1 has lethal phenotype

(Sefton et al., 2000)

sisA[+]/sisA¹, upd1^sisC-5/upd1^sisC-1, upd1^t4.8 has lethal phenotype

(Sefton et al., 2000)

sisA[+]/sisA¹, upd1^sisC-5/upd1^sisC-1, upd1^t10 has partially lethal phenotype

(Sefton et al., 2000)

sisA[+]/sisA¹, upd1^sisC-5/upd1^sisC-1, upd1^t5.8 has partially lethal phenotype

(Sefton et al., 2000)

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Maternal heterozygosity for Bap60¹ reduces the viability of female offspring which are doubly heterozygous for sisA¹ upd1^sisC-1.

(Möller et al., 2005)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 1 )

Crossreferences

GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.

AF231684

Synonyms and Secondary IDs (4)

Reported As

Symbol Synonym

os^sisC-1

os^sisC1

(Möller et al., 2005)

sisC¹

(Sefton et al., 2000)

upd1^sisC-1

Name Synonyms

Secondary FlyBase IDs

References (2)

Report Sections

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