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General Information
Symbol
Dmel\Bap601
Species
D. melanogaster
Name
FlyBase ID
FBal0248828
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Cytology
Nature of the lesion
Statement
Reference

Imprecise excision of the progenitor insertion, resulting in a 2kb deletion that removes the N-terminal portion of the Bap60 coding region and an N-terminal portion of the CG12096 gene.

Caused by aberration
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Approximately two-thirds of hemizygous male embryos die prior to hatching, while the remaining male hemizygotes die during early larval stages.

Eggs derived from females carrying homozygous germline clones are partially deformed or deflated and no larvae hatch from these eggs.

Bap601/+ completely suppresses the position effect variegation at the w locus which is caused by In(1)wm4h.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Enhancer of
Statement
Reference

Bap60[+]/Bap601 is an enhancer of visible | dominant phenotype of brm2

Bap60[+]/Bap601 is an enhancer of visible | dominant phenotype of brm2, trx[+]/trxE2

Bap60[+]/Bap601 is an enhancer of visible | dominant phenotype of mor1

Suppressor of
Statement
Reference

Bap60[+]/Bap601 is a suppressor | partially of visible | dominant phenotype of AntpNs

NOT Suppressor of
Statement
Reference

Bap60[+]/Bap601 is a non-suppressor of visible | dominant phenotype of Antp73b

Other
Phenotype Manifest In
Enhancer of
Statement
Reference

Bap60[+]/Bap601 is an enhancer of humeral bristle phenotype of brm2

Bap60[+]/Bap601 is an enhancer of humeral bristle phenotype of brm2, trx[+]/trxE2

Bap60[+]/Bap601 is an enhancer of humeral bristle phenotype of mor1

Suppressor of
Statement
Reference

Bap60[+]/Bap601 is a suppressor | partially of antenna phenotype of AntpNs

Bap60[+]/Bap601 is a suppressor | partially of leg | ectopic phenotype of AntpNs

NOT Suppressor of
Statement
Reference

Bap60[+]/Bap601 is a non-suppressor of antenna phenotype of Antp73b

Bap60[+]/Bap601 is a non-suppressor of leg | ectopic phenotype of Antp73b

Other
Statement
Reference
Additional Comments
Genetic Interactions
Statement
Reference

Stage 16 Bap601/+ ; akirinEP906/+ double heterozygous embryos show disruption of the somatic muscle pattern (20.2% of embryos have missing, misattached or duplicated muscles in at least 2 hemisegments).

The penetrance of the loss of humeral bristle phenotype seen in brm2/+ flies is increased by Bap601/+ from 7% to 14%.

5% of brm2 trxE2 double heterozygotes show loss of humeral bristles. The penetrance of this phenotype is increased to 15% by Bap601/+.

Bap601/+ ; trxE2/+ double heterozygotes do not show loss of humeral bristles.

The penetrance of the loss of humeral bristle phenotype seen in mor1/+ flies is increased by Bap601/+ from 3% to 7%.

The penetrance of the antenna to leg transformation phenotype seen in AntpNs/+ flies is slightly suppressed by Bap601/+ from 100% to 92%.

The antenna to leg transformation phenotype seen in Antp73b/+ flies is not suppressed by Bap601/+.

Maternal heterozygosity for Bap601 reduces the viability of female offspring which are doubly heterozygous for sisA1 upd1sisC-1.

Maternal heterozygosity for Bap601 reduces the viability of female offspring which are heterozygous for sisA1.

Maternal heterozygosity for Bap601 reduces the viability of female offspring which are heterozygous for Df(1)sc19.

Maternal heterozygosity for Bap601 reduces the viability of female offspring which are heterozygous for Df(1)sc10-1.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Rescued by
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (1)
Reported As
Symbol Synonym
Name Synonyms
Secondary FlyBase IDs
    References (2)