FlyBase Allele Report: Dmel\brm[2]

General Information

Symbol

Dmel\brm²

Species

D. melanogaster

Name

FlyBase ID

FBal0001296

Feature type

allele

Associated gene

Dmel\brm

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

amorphic allele - genetic evidence

Mutagen

ethyl methanesulfonate

Nature of the Allele

Allele class

amorphic allele - genetic evidence

(Ragab et al., 2006, Gindhart and Kaufman, 1995)

Mutagen

ethyl methanesulfonate

(Kennison and Tamkun, 1988)

Progenitor genotype

Cytology

Description

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal cell shape | recessive

(Tea and Luo, 2011)

abnormal mitotic cell cycle

(Remaud et al., 2008)

abnormal neuroanatomy | recessive

(Tea and Luo, 2011)

enhancer of variegation | dominant, with In(1)w^m4

(Nakayama et al., 2012)

enhancer of variegation | dominant, with P{hsp26-pt-T}39C-5

(Boivin et al., 2003)

enhancer of variegation | dominant, with P{hsp26-pt-T}39C-27

(Boivin et al., 2003)

enhancer of variegation | dominant, with P{hsp26-pt-T}39C-31

(Boivin et al., 2003)

enhancer of variegation | dominant, with P{wA}4-4

(Boivin et al., 2003)

homeotic | dominant

(Nakayama et al., 2012)

lethal | male (with brm^22D)

(Armstrong et al., 2005)

lethal | recessive

(Elfring et al., 1998, Brizuela et al., 1994, Kennison and Tamkun, 1988)

visible, with Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA}

(Armstrong et al., 2005)

visible | adult stage | dominant

(Bi et al., 2022)

visible | dominant

(Diop et al., 2008, Armstrong et al., 2005, Möller et al., 2005, Gutierrez et al., 2003)

visible | dominant | homeotic

(Ruhf et al., 2001)

visible | recessive | somatic clone

(Elfring et al., 1998)

visible | somatic clone

(Arancio et al., 2010)

Phenotype Manifest In

abdominal segment 6

(Ruhf et al., 2001)

abdominal tergite

(Bi et al., 2022)

adult abdominal segment 5 | ectopic

(Nakayama et al., 2012)

adult abdominal segment 6

(Nakayama et al., 2012)

adult antennal lobe projection neuron DL1 adPN

(Tea and Luo, 2011)

embryonic/larval hemocyte

(Remillieux-Leschelle et al., 2002)

eye, with Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA}

(Armstrong et al., 2005)

eye | somatic clone

(Arancio et al., 2010)

humeral bristle

(Möller et al., 2005)

intestinal stem cell of posterior adult midgut epithelium | somatic clone

(Jin et al., 2013)

macrochaeta

(Armstrong et al., 2005)

mechanosensory chaeta & adult abdomen | somatic clone

(Elfring et al., 1998)

mechanosensory chaeta & adult head | somatic clone

(Elfring et al., 1998)

mechanosensory chaeta & adult thorax | somatic clone

(Elfring et al., 1998)

ommatidium, with Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA}

(Armstrong et al., 2005)

wing

(Diop et al., 2008, Gutierrez et al., 2003)

Detailed Description

Statement

Reference

brm² heterozygotes do not show an ectopic scutellar bristle phenotype, as compared to controls.

(Mariappa et al., 2018)

The formation of ectopic wing veins observed in adult flies expressing Marcal1^Scer\UAS.cBa under the control of Scer\GAL4^tub.PU is ameliorated by combination with a single copy of brm².

(Morimoto et al., 2016)

brm² mutant intestinal stem cell clones in 3-day old flies contain fewer cells than controls (1-2 cells, compared to an average of 5), and are composed of all small nuclear cells rather than a mixture of large and small nuclear cells. The same is seen at 8 days, suggesting that enteroblast differentiation is affected.

(Jin et al., 2013)

brm²/+ enhances the position effect variegation at the w locus which is seen in In(1)w^m4 flies.

4% of heterozygous adult males show transformation of A6 to A5.

(Nakayama et al., 2012)

Heterozygotes have normal wings.

(Curtis et al., 2011)

PBac{GH146-GAL4.B}-marked anterodorsal single cell clones in brm² mutants display mistargeting to non-stereotyped glomeruli throughout the antennal lobe. PBac{GH146-GAL4.B}-marked neuroblast clones in brm² mutants display phenotypes where dendrites make small, meandering projections throughout the antennal lobe and exhibit perturbed cell morphology.

(Tea and Luo, 2011)

Female germline clones homozygous for brm² arrest their development early in oogenesis.

(Carrera et al., 2008)

brm²/+ mutant adults display a low penetrant (1.4%) "held-out" wing phenotype.

(Diop et al., 2008)

S-phase in secondary precursor cells in the bristle lineage is prolonged by around 30 minutes in brm² animals.

(Remaud et al., 2008)

3.5% of heterozygotes have ectopic or duplicated macrochaetae.

(Armstrong et al., 2005)

7% of heterozygotes show loss of humeral bristles.

(Möller et al., 2005)

brm²/+ enhances the telomeric position effect (TPE) of P{hsp26-pt-T}39C-5, P{hsp26-pt-T}39C-27, P{hsp26-pt-T}39C-31 and P{wA}4-4.

(Boivin et al., 2003)

2% of heterozygous flies have a held-out wings phenotype.

(Gutierrez et al., 2003)

2% of heterozygotes have a held-out wing phenotype.

(Calgaro et al., 2002)

Heterozygotes have normal lymph glands, but the concentration of circulating hemocytes is reduced compared to controls.

(Remillieux-Leschelle et al., 2002)

Transformation of abdominal segment A6 to A5.

(Ruhf et al., 2001)

Shows no dominant effect on telomeric Position Effect Variegation (PEV) in stocks carrying a variegating w^+mW.hs allele at the telomeres of the second and third chromosomes.

(Cryderman et al., 1999)

The size and frequency of homozygous clones in the head and thoracic segments are significantly reduced compared to controls. The size and frequency of homozygous and control clones in the abdomen are similar. The mechanosensory bristles of homozygous clones in the head, thoracic and abdominal segments are either duplicated, stunted or fused.

(Elfring et al., 1998)

No effect on the eye pigment phenotype of w^T81.

(Netter et al., 1998)

Pairing sensitive repression is unchanged in iab-7 PRE lines that carry brm².

(Hagstrom et al., 1997)

Mutation changes the level of w expression in ph-p^lac+3 flies; eye colour is lighter.

(Fauvarque et al., 1995)

Majority of lethality is observed during embryogenesis. There are no major abnormalities in formation or identity of the trunk segments. Formation of larval head structures is abnormal but the nature of the defects is undetermined.

(Brizuela et al., 1994)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhanced by

Statement

Reference

brm² has visible | adult stage | dominant phenotype, enhanceable by CtBP[+]/CtBP^87De-10

(Bi et al., 2022)

brm² has visible | dominant phenotype, enhanceable by pont[+]/pont^5.1

(Diop et al., 2008)

brm² has visible | dominant phenotype, enhanceable by pont^D302N.UAS/Scer\GAL4^arm.PS

(Diop et al., 2008)

brm² has visible | dominant phenotype, enhanceable by Df(3L)ZN47/+

(Armstrong et al., 2005)

brm² has visible | dominant phenotype, enhanceable by Delta²³⁷¹/Dl[+]

(Armstrong et al., 2005)

brm² has visible | dominant phenotype, enhanceable by Delta²⁶⁶/Dl[+]

(Armstrong et al., 2005)

brm² has visible | dominant phenotype, enhanceable by vn[+]/vn⁶⁴³

(Armstrong et al., 2005)

brm² has visible | dominant phenotype, enhanceable by Delta^9P/Dl[+]

(Armstrong et al., 2005)

brm² has visible | dominant phenotype, enhanceable by mor[+]/mor⁴

(Armstrong et al., 2005)

brm² has visible | dominant phenotype, enhanceable by Bap60[+]/Bap60¹

(Möller et al., 2005)

brm², trx[+]/trx^E2 has visible | dominant phenotype, enhanceable by Bap60[+]/Bap60¹

(Möller et al., 2005)

brm² has visible | dominant phenotype, enhanceable by tna¹

(Gutierrez et al., 2003)

brm² has visible | dominant phenotype, enhanceable by osa¹

(Gutierrez et al., 2003)

brm² has visible | dominant phenotype, enhanceable by tna^S058302/tara⁰³⁸⁸¹

(Gutierrez et al., 2003)

brm² has visible | dominant phenotype, enhanceable by tara²⁰

(Gutierrez et al., 2003)

brm² has visible | dominant phenotype, enhanceable by tna^S058302/tara²⁰

(Gutierrez et al., 2003)

brm² has visible | dominant phenotype, enhanceable by tara²

(Gutierrez et al., 2003)

brm² has visible | dominant phenotype, enhanceable by tna^S058302/tara²

(Gutierrez et al., 2003)

brm[+]/brm², trx^E2 has visible | dominant | homeotic phenotype, enhanceable by JIL-1[+]/JIL-1^z2

(Zhang et al., 2003)

brm[+]/brm², tara^L4 has visible | dominant phenotype, enhanceable by trx[+]/trx^E2

(Calgaro et al., 2002)

brm[+]/brm², trx^E2 has visible | dominant | homeotic phenotype, enhanceable by Asx[+]/Asx¹³

(Gildea et al., 2000)

brm[+]/brm², trx^E2 has visible | dominant | homeotic phenotype, enhanceable by Asx³/Asx[+]

(Gildea et al., 2000)

brm[+]/brm², trx^E2 has visible | dominant | homeotic phenotype, enhanceable by E(z)[+]/E(z)⁵

(Gildea et al., 2000)

brm[+]/brm², trx^E2 has visible | dominant | homeotic phenotype, enhanceable by Psc[+]/Psc¹

(Gildea et al., 2000)

brm[+]/brm², trx^E2 has visible | dominant | homeotic phenotype, enhanceable by Sce[+]/Sce^D1

(Gildea et al., 2000)

brm[+]/brm², trx^E2 has visible | dominant | homeotic phenotype, enhanceable by Su(z)2¹/Su(z)2[+]

(Gildea et al., 2000)

brm[+]/brm², trx^E2 has visible | dominant | homeotic phenotype, enhanceable by Su(z)2^Arp1/Su(z)2[+]

(Gildea et al., 2000)

brm[+]/brm², trx^E2 has visible | dominant | homeotic phenotype, enhanceable by Su(z)4[+]/Su(z)4¹

(Gildea et al., 2000)

brm[+]/brm², trx^E2 has visible | dominant | homeotic phenotype, enhanceable by Su(z)6[+]/Su(z)6¹

(Gildea et al., 2000)

brm[+]/brm², trx^E2 has visible | dominant | homeotic phenotype, enhanceable by Su(z)7[+]/Su(z)7¹

(Gildea et al., 2000)

brm[+]/brm², trx^E2 has visible | dominant | homeotic phenotype, enhanceable by Trl[+]/Trl^R85

(Gildea et al., 2000)

brm[+]/brm², trx^E2 has visible | dominant | homeotic phenotype, enhanceable by sxc[+]/sxc¹

(Gildea et al., 2000)

brm[+]/brm², trx^E2 has visible | dominant | homeotic phenotype, enhanceable by E(Pc)[+]/E(Pc)¹

(Gildea et al., 2000)

brm[+]/brm², trx^E2 has visible | dominant | homeotic phenotype, enhanceable by Kdm5^k06801/lid[+]

(Gildea et al., 2000)

brm², lawc^p1 has visible | homeotic phenotype, enhanceable by trx^E2

(Zorin et al., 1999)

brm², trx[+]/trx^E2 has visible | dominant | homeotic phenotype, enhanceable by lawc^p1/lawc[+]

(Zorin et al., 1999)

brm[+]/brm², trx^E2 has visible | dominant | homeotic phenotype, enhanceable by lawc^p1/lawc[+]

(Zorin et al., 1999)

brm[+]/brm², trx^E2 has visible | dominant | homeotic phenotype, enhanceable by lawc[+]/lawc^EF520

(Zorin et al., 1999)

brm², trx[+]/trx^E2 has visible | dominant | homeotic phenotype, enhanceable by lawc[+]/lawc^EF520

(Zorin et al., 1999)

brm[+]/brm², trx^E2 has visible | dominant | homeotic phenotype, enhanceable by Df(1)RA2/+

(Zorin et al., 1999)

brm², trx[+]/trx^E2 has visible | dominant | homeotic phenotype, enhanceable by Df(1)RA2/+

(Zorin et al., 1999)

brm², trx[+]/trx^E2 has visible | dominant | homeotic phenotype, enhanceable by mod(mdg4)^T16/mod(mdg4)[+]

(Gerasimova and Corces, 1998)

brm², trx[+]/trx^E2 has visible | dominant | homeotic phenotype, enhanceable by mod(mdg4)[+]/mod(mdg4)^ul

(Gerasimova and Corces, 1998)

brm², trx[+]/trx^E2 has visible | dominant | homeotic phenotype, enhanceable by mod(mdg4)[+]/mod(mdg4)^T6

(Gerasimova and Corces, 1998)

brm[+]/brm², trx^E2 has visible | dominant | homeotic phenotype, enhanceable by mod(mdg4)^T16/mod(mdg4)[+]

(Gerasimova and Corces, 1998)

brm[+]/brm², trx^E2 has visible | dominant | homeotic phenotype, enhanceable by mod(mdg4)[+]/mod(mdg4)^ul

(Gerasimova and Corces, 1998)

brm[+]/brm², trx^E2 has visible | dominant | homeotic phenotype, enhanceable by mod(mdg4)[+]/mod(mdg4)^T6

(Gerasimova and Corces, 1998)

brm², mod(mdg4)^ul, y² has abnormal body color phenotype, enhanceable by trx^E2

(Gerasimova and Corces, 1998)

NOT Enhanced by

Statement

Reference

brm² has visible | adult stage | dominant phenotype, non-enhanceable by Df(3R)Exel8157/+

(Bi et al., 2022)

brm² has visible | dominant phenotype, non-enhanceable by rept³⁵/rept[+]/pont[+]/pont^5.1

(Diop et al., 2008)

brm² has visible | dominant phenotype, non-enhanceable by tna^S058302

(Gutierrez et al., 2003)

brm² has visible | homeotic phenotype, non-enhanceable by lawc^p1

(Zorin et al., 1999)

brm² has visible | dominant | homeotic phenotype, non-enhanceable by lawc^p1

(Zorin et al., 1999)

brm² has visible | dominant | homeotic phenotype, non-enhanceable by lawc^EF520

(Zorin et al., 1999)

brm² has visible | dominant | homeotic phenotype, non-enhanceable by lawc⁺¹⁰

(Zorin et al., 1999)

brm² has visible | dominant | homeotic phenotype, non-enhanceable by Df(1)RA2

(Zorin et al., 1999)

Suppressed by

Statement

Reference

brm[+]/brm², trx^E2 has homeotic | dominant phenotype, suppressible by CG9007[+]/upSET^e00365

(Rincon-Arano et al., 2012)

brm[+]/brm², trx^E2 has homeotic | dominant phenotype, suppressible by upSET^MB08950/CG9007[+]

(Rincon-Arano et al., 2012)

brm², pont[+]/pont^5.1 has visible | dominant phenotype, suppressible by pont^UAS.cDa/Scer\GAL4^arm.PS

(Diop et al., 2008)

brm², rept³⁵/rept[+] has visible | dominant phenotype, suppressible by rept^UAS.cDa/Scer\GAL4^arm.PS

(Diop et al., 2008)

brm² has visible | dominant phenotype, suppressible by rept³⁵/rept[+]

(Diop et al., 2008)

brm[+]/brm², trx^E2 has visible | dominant | homeotic phenotype, suppressible by dom¹⁴/dom[+]

(Ruhf et al., 2001)

brm², trx[+]/trx^E2 has visible | dominant | homeotic phenotype, suppressible by dom¹⁴/dom[+]

(Ruhf et al., 2001)

brm² has visible | homeotic phenotype, suppressible by dom¹⁴/dom[+]

(Ruhf et al., 2001)

brm[+]/brm², trx^E2 has visible | dominant | homeotic phenotype, suppressible by M(2)21AB[+]/Sams¹

(Gildea et al., 2000)

brm[+]/brm², trx^E2 has visible | dominant | homeotic phenotype, suppressible by Pc³/Pc[+]

(Gildea et al., 2000)

brm[+]/brm², trx^E2 has visible | dominant | homeotic phenotype, suppressible by Pcl⁷/Pcl[+]

(Gildea et al., 2000)

brm[+]/brm², trx^E2 has visible | dominant | homeotic phenotype, suppressible by esc¹⁰/esc[+]

(Gildea et al., 2000)

brm[+]/brm², trx^E2 has visible | dominant | homeotic phenotype, suppressible by esc²¹/esc[+]

(Gildea et al., 2000)

brm[+]/brm², trx^E2 has visible | dominant | homeotic phenotype, suppressible by esc⁹/esc[+]

(Gildea et al., 2000)

brm[+]/brm², trx^E2 has visible | dominant | homeotic phenotype, suppressible by mxc[+]/mxc¹

(Gildea et al., 2000)

brm[+]/brm², trx^E2 has visible | dominant | homeotic phenotype, suppressible by mxc[+]/mxc^M1

(Gildea et al., 2000)

brm[+]/brm², trx^E2 has visible | dominant | homeotic phenotype, suppressible by ph-d[+]/ph-d⁵⁰³

(Gildea et al., 2000)

brm[+]/brm², trx^E2 has visible | dominant | homeotic phenotype, suppressible by pho^b/pho[+]

(Gildea et al., 2000)

brm[+]/brm², trx^E2 has visible | dominant | homeotic phenotype, suppressible by sxc[+]/sxc⁴

(Gildea et al., 2000)

Enhancer of

Statement

Reference

brm[+]/brm² is an enhancer of abnormal neuroanatomy phenotype of brat^DG19310/brat¹¹

(Janssens et al., 2014)

brm[+]/brm² is an enhancer of abnormal neuroanatomy phenotype of numb^NP2301

(Janssens et al., 2014)

brm² is an enhancer of visible phenotype of sd¹

(Jin et al., 2013)

brm[+]/brm² is an enhancer of visible | dominant phenotype of gcm^Pyx

(Popkova et al., 2012)

osa², osa[+], brm[+], brm² is an enhancer of visible | dominant phenotype of gcm^Pyx

(Popkova et al., 2012)

brm[+]/brm² is an enhancer of visible phenotype of Df(2L)3G/γTub23C^A14-9

(Vázquez et al., 2008)

brm[+]/brm² is an enhancer of visible | dominant phenotype of Delta²³⁷¹

(Armstrong et al., 2005)

brm[+]/brm² is an enhancer of visible | dominant phenotype of mor⁴

(Armstrong et al., 2005)

brm[+]/brm² is an enhancer of visible | dominant phenotype of Delta^9P

(Armstrong et al., 2005)

brm[+]/brm² is an enhancer of visible | dominant phenotype of Delta²⁶⁶

(Armstrong et al., 2005)

brm[+]/brm² is an enhancer of visible phenotype of ct^53d

(Krupp et al., 2005)

brm² is an enhancer of visible phenotype of H^UAS.cMa, Scer\GAL4^GMR.PF

(Müller et al., 2005)

brm² is an enhancer of visible | dominant phenotype of tna¹

(Gutierrez et al., 2003)

brm² is an enhancer of visible | dominant phenotype of osa¹

(Gutierrez et al., 2003)

brm² is an enhancer of visible phenotype of BacA\p35^GMR.PH, Dp^GMR.PD, E2f1^GMR.PD

(Staehling-Hampton et al., 1999)

trx[+], trx^E2, brm[+], brm² is an enhancer of visible | homeotic phenotype of lawc^p1

(Zorin et al., 1999)

NOT Enhancer of

Statement

Reference

brm[+]/brm² is a non-enhancer of visible phenotype of E2f1^UAS.cNa, Scer\GAL4^Act88F.PD

(Ji et al., 2012)

brm[+]/brm² is a non-enhancer of visible phenotype of Dp^UAS.cDa, E2f1^UAS.cNa, Scer\GAL4^GMR.PU

(Ji et al., 2012)

brm[+]/brm² is a non-enhancer of visible phenotype of ct^K

(Krupp et al., 2005)

brm[+]/brm² is a non-enhancer of visible | homeotic phenotype of Dsp1¹

(Decoville et al., 2001)

brm² is a non-enhancer of visible phenotype of BEAF-32^UAS.cYa, Scer\GAL4^GMR.PS

(Yamaguchi et al., 2001)

Suppressor of

Statement

Reference

brm[+]/brm² is a suppressor of visible | adult stage phenotype of Marcal1^UAS.cBa, Scer\GAL4^Tub.PU

(Morimoto et al., 2016)

brm[+]/brm² is a suppressor of visible | adult stage phenotype of Hsap\SMARCAL1^UAS.cBa, Scer\GAL4^Bx-MS1096

(Morimoto et al., 2016)

brm[+]/brm² is a suppressor of visible phenotype of E2f1^RNAi.UAS.cJa, Scer\GAL4^GMR.PU

(Ji et al., 2012)

brm[+]/brm² is a suppressor of visible phenotype of E2f1^RNAi.UAS.cJa, Scer\GAL4^ptc-559.1

(Ji et al., 2012)

brm[+]/brm² is a suppressor of visible | dominant phenotype of Snr1^E1

(Curtis et al., 2011)

brm[+]/brm², Scer\GAL4^bbg-C96 is a suppressor | partially of visible phenotype of Raf^UAS.F179, Scer\GAL4^bbg-C96

(Herr et al., 2010)

brm[+]/brm² is a suppressor of visible | dominant phenotype of Egfr^E3

(Herr et al., 2010)

brm² is a suppressor of visible phenotype of Myc^UAS.cZa, Scer\GAL4^GMR.PF

(Secombe et al., 2007)

brm² is a suppressor | partially of visible | dominant phenotype of HDAC3^B, Snr1^E1/Snr1[+]

(Zraly et al., 2004)

brm² is a suppressor | partially of visible | dominant phenotype of HDAC1⁰⁴⁵⁵⁶, Snr1^R3/Snr1[+]

(Zraly et al., 2004)

brm² is a suppressor | partially of visible | dominant phenotype of HDAC1⁰⁴⁵⁵⁶, Snr1^E1/Snr1[+]

(Zraly et al., 2004)

brm[+]/brm² is a suppressor of increased cell death phenotype of Dref^UAS.cSa, Scer\GAL4^GMR.PS

(Hirose et al., 2001)

brm² is a suppressor of lethal phenotype of Ras85D^V12.sev, sev^S11.Tag:MYC

(Maixner et al., 1998)

NOT Suppressor of

Statement

Reference

brm[+]/brm² is a non-suppressor of visible phenotype of Dp^UAS.cDa, E2f1^UAS.cNa, Scer\GAL4^GMR.PU

(Ji et al., 2012)

brm[+]/brm² is a non-suppressor of visible phenotype of E2f1^UAS.cNa, Scer\GAL4^Act88F.PD

(Ji et al., 2012)

brm[+]/brm² is a non-suppressor of visible phenotype of ct^K

(Krupp et al., 2005)

brm² is a non-suppressor of visible phenotype of BEAF-32^UAS.cYa, Scer\GAL4^GMR.PS

(Yamaguchi et al., 2001)

Other

Statement

Reference

Rel^E20, brm[+]/brm² has abnormal immune response phenotype

(Bonnay et al., 2014)

Rel^E20, brm[+]/brm² has short lived | conditional phenotype

(Bonnay et al., 2014)

brm[+]/brm², trx^E2 has homeotic | dominant phenotype

(Rincon-Arano et al., 2012)

Su(var)3-3[+]/Su(var)3-3^ΔN, brm² has visible | dominant phenotype

(Curtis et al., 2011)

γTub23C^Pl-2, brm² has visible | dominant phenotype

(Vázquez et al., 2008)

γTub23C^Pl-2, brm[+]/brm², osa¹/osa[+] has visible | dominant phenotype

(Vázquez et al., 2008)

Egfr^f2, brm[+]/brm² has visible phenotype

(Armstrong et al., 2005)

Df(3L)ZN47/+, brm² has visible | dominant phenotype

(Armstrong et al., 2005)

Delta²³⁷¹/Dl[+], brm² has visible | dominant phenotype

(Armstrong et al., 2005)

Delta²⁶⁶/Dl[+], brm² has visible | dominant phenotype

(Armstrong et al., 2005)

Egfr[+]/Egfr^f2, brm² has visible | dominant phenotype

(Armstrong et al., 2005)

brm², vn[+]/vn¹⁰⁵⁶⁷ has visible | dominant phenotype

(Armstrong et al., 2005)

brm², vn[+]/vn⁶⁴³ has visible | dominant phenotype

(Armstrong et al., 2005)

brm², vn[+]/vn^C221 has visible | dominant phenotype

(Armstrong et al., 2005)

brm², mor[+]/mor⁴ has visible | dominant phenotype

(Armstrong et al., 2005)

brm[+]/brm², mor⁴ has visible phenotype

(Armstrong et al., 2005)

brm[+]/brm², vn¹⁰⁵⁶⁷ has visible phenotype

(Armstrong et al., 2005)

brm[+]/brm², vn^C221 has visible phenotype

(Armstrong et al., 2005)

brm[+]/brm², vn⁶⁴³ has visible phenotype

(Armstrong et al., 2005)

Delta²³⁷¹, brm[+]/brm² has visible phenotype

(Armstrong et al., 2005)

Delta²⁶⁶, brm[+]/brm² has visible phenotype

(Armstrong et al., 2005)

brm², trx[+]/trx^E2 has visible | dominant phenotype

(Möller et al., 2005, Calgaro et al., 2002)

brm[+]/brm², trx^E2 has visible | dominant | homeotic phenotype

(Zhang et al., 2003)

brm², trx[+]/trx^E2 has visible | dominant | homeotic phenotype

(Zhang et al., 2003)

brm², tara¹/tara[+] has visible | dominant phenotype

(Calgaro et al., 2002)

brm², tara¹/tara[+], trx[+]/trx^E2 has visible | dominant phenotype

(Calgaro et al., 2002)

brm², tara^L4/tara[+], trx[+]/trx^E2 has visible | dominant phenotype

(Calgaro et al., 2002)

brm², tara^L4/tara[+] has visible | dominant phenotype

(Calgaro et al., 2002)

brm², tara¹ has visible | dominant phenotype

(Calgaro et al., 2002)

brm[+]/brm², tara¹, trx[+]/trx^E2 has visible | dominant phenotype

(Calgaro et al., 2002)

brm², tara^L4 has visible | dominant phenotype

(Calgaro et al., 2002)

brm[+]/brm², tara¹/tara[+], trx^E2 has visible | dominant phenotype

(Calgaro et al., 2002)

brm[+]/brm², tara^L4/tara[+], trx^E2 has visible | dominant phenotype

(Calgaro et al., 2002)

brm², trx^E2 has visible | dominant phenotype

(Calgaro et al., 2002, Vazquez et al., 1999)

Asx¹³, brm² has visible | dominant | homeotic phenotype

(Gildea et al., 2000)

Asx³/Asx[+], brm² has visible | dominant | homeotic phenotype

(Gildea et al., 2000)

Asx^XF23/Asx[+], brm² has visible | dominant | homeotic phenotype

(Gildea et al., 2000)

+/Df(2L)Mdh, brm² has visible | dominant | homeotic phenotype

(Gildea et al., 2000)

Df(2L)cl-h3/+, brm² has visible | dominant | homeotic phenotype

(Gildea et al., 2000)

Df(2R)Pu-D17/+, brm² has visible | dominant | homeotic phenotype

(Gildea et al., 2000)

Df(2R)or-BR6/+, brm² has visible | dominant | homeotic phenotype

(Gildea et al., 2000)

Df(3L)Ar14-8/+, brm² has visible | dominant | homeotic phenotype

(Gildea et al., 2000)

E(Pc)[+]/E(Pc)¹, brm² has visible | dominant | homeotic phenotype

(Gildea et al., 2000)

Psc[+]/Psc¹, brm² has visible | dominant | homeotic phenotype

(Gildea et al., 2000)

Sce[+]/Sce^D1, brm² has visible | dominant | homeotic phenotype

(Gildea et al., 2000)

Su(z)2¹/Su(z)2[+], brm² has visible | dominant | homeotic phenotype

(Gildea et al., 2000)

Su(z)6[+]/Su(z)6¹, brm² has visible | dominant | homeotic phenotype

(Gildea et al., 2000)

Su(z)7[+]/Su(z)7¹, brm² has visible | dominant | homeotic phenotype

(Gildea et al., 2000)

Trl[+]/Trl^R85, brm² has visible | dominant | homeotic phenotype

(Gildea et al., 2000)

Kdm5^k06801/lid[+], brm² has visible | dominant | homeotic phenotype

(Gildea et al., 2000)

Psc¹, brm² has visible | dominant | homeotic phenotype

(Gildea et al., 2000)

Kdm5^k06801, brm² has visible | dominant | homeotic phenotype

(Gildea et al., 2000)

Asx³, brm² has visible | dominant | homeotic phenotype

(Gildea et al., 2000)

Su(z)2¹, brm² has visible | dominant | homeotic phenotype

(Gildea et al., 2000)

Sce^D1, brm[+]/brm² has visible | dominant | homeotic phenotype

(Gildea et al., 2000)

Asx^XF23, brm² has visible | dominant | homeotic phenotype

(Gildea et al., 2000)

Su(z)6¹, brm² has visible | dominant | homeotic phenotype

(Gildea et al., 2000)

Su(z)7¹, brm² has visible | dominant | homeotic phenotype

(Gildea et al., 2000)

Trl^R85, brm² has visible | dominant | homeotic phenotype

(Gildea et al., 2000)

E(Pc)¹, brm² has visible | dominant | homeotic phenotype

(Gildea et al., 2000)

Sce^D1, brm² has visible | dominant | homeotic phenotype

(Gildea et al., 2000)

Asx[+]/Asx¹³, brm² has visible | dominant | homeotic phenotype

(Gildea et al., 2000)

brm², trx^E2 has visible | homeotic phenotype

(Zorin et al., 1999, Gerasimova and Corces, 1998, Tamkun et al., 1992)

ash1⁶, brm² has visible | dominant phenotype

(Vazquez et al., 1999)

brm², osa¹¹ has visible | dominant phenotype

(Vazquez et al., 1999)

brm², osa¹ has visible | dominant phenotype

(Vazquez et al., 1999)

brm², osa² has visible | dominant phenotype

(Vazquez et al., 1999)

brm², osa¹² has visible | dominant phenotype

(Vazquez et al., 1999)

brm², mor¹ has visible | dominant phenotype

(Vazquez et al., 1999)

brm², mor² has visible | dominant phenotype

(Vazquez et al., 1999)

brm², lawc^p1/lawc^EF520 has lethal phenotype

(Zorin et al., 1999)

Df(1)RA2/lawc^p1, brm² has lethal phenotype

(Zorin et al., 1999)

Ras85D^V12.sev, brm², sev^S11.Tag:MYC has viable phenotype

(Maixner et al., 1998)

ash1^unspecified, brm[+]/brm² has visible | homeotic phenotype

(Tripoulas et al., 1996)

ash1^unspecified/ash1[+], brm² has visible | homeotic phenotype

(Tripoulas et al., 1996)

ash1[+]/ash1¹, brm² has visible | homeotic phenotype

(Tripoulas et al., 1994)

ash1[+]/ash1⁶, brm² has visible | homeotic phenotype

(Tripoulas et al., 1994)

ash1²⁸/ash1[+], brm² has visible | homeotic phenotype

(Tripoulas et al., 1994)

Phenotype Manifest In

Enhanced by

Statement

Reference

brm² has abdominal tergite phenotype, enhanceable by CtBP[+]/CtBP^87De-10

(Bi et al., 2022)

brm² has wing phenotype, enhanceable by pont[+]/pont^5.1

(Diop et al., 2008)

brm² has wing phenotype, enhanceable by pont^D302N.UAS/Scer\GAL4^arm.PS

(Diop et al., 2008)

brm² has phenotype, enhanceable by +/Df(3L)vtd¹⁴

(Hallson et al., 2008)

brm² has macrochaeta phenotype, enhanceable by Df(3L)ZN47/+

(Armstrong et al., 2005)

brm² has macrochaeta phenotype, enhanceable by Delta²³⁷¹/Dl[+]

(Armstrong et al., 2005)

brm² has macrochaeta phenotype, enhanceable by Delta²⁶⁶/Dl[+]

(Armstrong et al., 2005)

brm² has macrochaeta phenotype, enhanceable by vn[+]/vn⁶⁴³

(Armstrong et al., 2005)

brm² has macrochaeta phenotype, enhanceable by Delta^9P/Dl[+]

(Armstrong et al., 2005)

brm² has macrochaeta phenotype, enhanceable by mor[+]/mor⁴

(Armstrong et al., 2005)

brm² has humeral bristle phenotype, enhanceable by Bap60[+]/Bap60¹

(Möller et al., 2005)

brm², trx[+]/trx^E2 has humeral bristle phenotype, enhanceable by Bap60[+]/Bap60¹

(Möller et al., 2005)

brm² has wing phenotype, enhanceable by tna¹

(Gutierrez et al., 2003)

brm² has wing phenotype, enhanceable by osa¹

(Gutierrez et al., 2003)

brm² has wing phenotype, enhanceable by tna^S058302/tara⁰³⁸⁸¹

(Gutierrez et al., 2003)

brm² has wing phenotype, enhanceable by tara²⁰

(Gutierrez et al., 2003)

brm² has wing phenotype, enhanceable by tna^S058302/tara²⁰

(Gutierrez et al., 2003)

brm² has wing phenotype, enhanceable by tara²

(Gutierrez et al., 2003)

brm² has wing phenotype, enhanceable by tna^S058302/tara²

(Gutierrez et al., 2003)

brm[+]/brm², trx^E2 has adult abdominal segment 5 | ectopic | male phenotype, enhanceable by JIL-1[+]/JIL-1^z2

(Zhang et al., 2003)

brm[+]/brm², trx^E2 has adult abdominal segment 6 | male phenotype, enhanceable by JIL-1[+]/JIL-1^z2

(Zhang et al., 2003)

brm[+]/brm², tara^L4 has wing phenotype, enhanceable by trx[+]/trx^E2

(Calgaro et al., 2002)

brm[+]/brm², trx^E2 has adult metathoracic segment phenotype, enhanceable by Asx[+]/Asx¹³

(Gildea et al., 2000)

brm[+]/brm², trx^E2 has adult metathoracic segment phenotype, enhanceable by Asx³/Asx[+]

(Gildea et al., 2000)

brm[+]/brm², trx^E2 has adult metathoracic segment phenotype, enhanceable by E(z)[+]/E(z)⁵

(Gildea et al., 2000)

brm[+]/brm², trx^E2 has adult metathoracic segment phenotype, enhanceable by Psc[+]/Psc¹

(Gildea et al., 2000)

brm[+]/brm², trx^E2 has adult metathoracic segment phenotype, enhanceable by Sce[+]/Sce^D1

(Gildea et al., 2000)

brm[+]/brm², trx^E2 has adult metathoracic segment phenotype, enhanceable by Su(z)2¹/Su(z)2[+]

(Gildea et al., 2000)

brm[+]/brm², trx^E2 has adult metathoracic segment phenotype, enhanceable by Su(z)2^Arp1/Su(z)2[+]

(Gildea et al., 2000)

brm[+]/brm², trx^E2 has adult metathoracic segment phenotype, enhanceable by Su(z)4[+]/Su(z)4¹

(Gildea et al., 2000)

brm[+]/brm², trx^E2 has adult metathoracic segment phenotype, enhanceable by Su(z)6[+]/Su(z)6¹

(Gildea et al., 2000)

brm[+]/brm², trx^E2 has adult metathoracic segment phenotype, enhanceable by Su(z)7[+]/Su(z)7¹

(Gildea et al., 2000)

brm[+]/brm², trx^E2 has adult metathoracic segment phenotype, enhanceable by Trl[+]/Trl^R85

(Gildea et al., 2000)

brm[+]/brm², trx^E2 has adult metathoracic segment phenotype, enhanceable by sxc[+]/sxc¹

(Gildea et al., 2000)

brm[+]/brm², trx^E2 has adult metathoracic segment phenotype, enhanceable by E(Pc)[+]/E(Pc)¹

(Gildea et al., 2000)

brm[+]/brm², trx^E2 has adult metathoracic segment phenotype, enhanceable by Kdm5^k06801/lid[+]

(Gildea et al., 2000)

brm², lawc^p1 has arista phenotype, enhanceable by trx^E2

(Zorin et al., 1999)

brm², trx^B11/trx[+] has haltere phenotype, enhanceable by lawc^p1/lawc[+]

(Zorin et al., 1999)

brm², trx^B11/trx[+] has metathoracic leg phenotype, enhanceable by lawc^p1/lawc[+]

(Zorin et al., 1999)

brm[+]/brm², trx^E2 has haltere phenotype, enhanceable by lawc^p1/lawc[+]

(Zorin et al., 1999)

brm[+]/brm², trx^E2 has metathoracic leg phenotype, enhanceable by lawc^p1/lawc[+]

(Zorin et al., 1999)

brm², mod(mdg4)^ul, y² has adult cuticle | male phenotype, enhanceable by trx^E2

(Gerasimova and Corces, 1998)

NOT Enhanced by

Statement

Reference

brm² has abdominal tergite phenotype, non-enhanceable by Df(3R)Exel8157/+

(Bi et al., 2022)

brm² has wing phenotype, non-enhanceable by rept³⁵/rept[+]/pont[+]/pont^5.1

(Diop et al., 2008)

brm² has wing phenotype, non-enhanceable by tna^S058302

(Gutierrez et al., 2003)

Suppressed by

Statement

Reference

brm[+]/brm², trx^E2 has metathoracic leg phenotype, suppressible by CG9007[+]/upSET^e00365

(Rincon-Arano et al., 2012)

brm[+]/brm², trx^E2 has metathoracic leg phenotype, suppressible by upSET^MB08950/CG9007[+]

(Rincon-Arano et al., 2012)

brm², pont[+]/pont^5.1 has wing phenotype, suppressible by pont^UAS.cDa/Scer\GAL4^arm.PS

(Diop et al., 2008)

brm², rept³⁵/rept[+] has wing phenotype, suppressible by rept^UAS.cDa/Scer\GAL4^arm.PS

(Diop et al., 2008)

brm² has wing phenotype, suppressible by rept³⁵/rept[+]

(Diop et al., 2008)

brm², rho^ve-1 has wing vein L5 phenotype, suppressible by Snr1^E1

(Marenda et al., 2004)

brm[+]/brm², trx^E2 has abdominal segment 6 phenotype, suppressible by dom¹⁴/dom[+]

(Ruhf et al., 2001)

brm[+]/brm², trx^E2 has haltere phenotype, suppressible by dom¹⁴/dom[+]

(Ruhf et al., 2001)

brm², trx[+]/trx^E2 has abdominal segment 6 phenotype, suppressible by dom¹⁴/dom[+]

(Ruhf et al., 2001)

brm², trx[+]/trx^E2 has haltere phenotype, suppressible by dom¹⁴/dom[+]

(Ruhf et al., 2001)

brm² has abdominal segment 6 phenotype, suppressible by dom¹⁴/dom[+]

(Ruhf et al., 2001)

brm[+]/brm², trx^E2 has adult metathoracic segment phenotype, suppressible by M(2)21AB[+]/Sams¹

(Gildea et al., 2000)

brm[+]/brm², trx^E2 has adult metathoracic segment phenotype, suppressible by Pc³/Pc[+]

(Gildea et al., 2000)

brm[+]/brm², trx^E2 has adult metathoracic segment phenotype, suppressible by Pcl⁷/Pcl[+]

(Gildea et al., 2000)

brm[+]/brm², trx^E2 has adult metathoracic segment phenotype, suppressible by esc¹⁰/esc[+]

(Gildea et al., 2000)

brm[+]/brm², trx^E2 has adult metathoracic segment phenotype, suppressible by esc²¹/esc[+]

(Gildea et al., 2000)

brm[+]/brm², trx^E2 has adult metathoracic segment phenotype, suppressible by esc⁹/esc[+]

(Gildea et al., 2000)

brm[+]/brm², trx^E2 has adult metathoracic segment phenotype, suppressible by mxc[+]/mxc¹

(Gildea et al., 2000)

brm[+]/brm², trx^E2 has adult metathoracic segment phenotype, suppressible by mxc[+]/mxc^M1

(Gildea et al., 2000)

brm[+]/brm², trx^E2 has adult metathoracic segment phenotype, suppressible by ph-d[+]/ph-d⁵⁰³

(Gildea et al., 2000)

brm[+]/brm², trx^E2 has adult metathoracic segment phenotype, suppressible by pho^b/pho[+]

(Gildea et al., 2000)

brm[+]/brm², trx^E2 has adult metathoracic segment phenotype, suppressible by sxc[+]/sxc⁴

(Gildea et al., 2000)

Enhancer of

Statement

Reference

brm[+]/brm² is an enhancer of type II neuroblast | increased number phenotype of brat^DG19310/brat¹¹

(Janssens et al., 2014)

brm[+]/brm² is an enhancer of type II neuroblast | increased number phenotype of numb^NP2301

(Janssens et al., 2014)

brm² is an enhancer of wing phenotype of sd¹

(Jin et al., 2013)

brm[+]/brm² is an enhancer of chaeta | increased number phenotype of gcm^Pyx

(Popkova et al., 2012)

osa², osa[+], brm[+], brm² is an enhancer of chaeta | increased number phenotype of gcm^Pyx

(Popkova et al., 2012)

brm[+]/brm² is an enhancer of leg phenotype of e(y)3⁴

(Chalkley et al., 2008)

brm[+]/brm² is an enhancer of wing phenotype of Df(2L)3G/γTub23C^A14-9

(Vázquez et al., 2008)

brm[+]/brm² is an enhancer of macrochaeta phenotype of Delta²³⁷¹

(Armstrong et al., 2005)

brm[+]/brm² is an enhancer of ommatidium phenotype of Delta²³⁷¹

(Armstrong et al., 2005)

brm[+]/brm² is an enhancer of humeral bristle phenotype of vn^C221

(Armstrong et al., 2005)

brm[+]/brm² is an enhancer of macrochaeta phenotype of mor⁴

(Armstrong et al., 2005)

brm[+]/brm² is an enhancer of macrochaeta phenotype of Delta^9P

(Armstrong et al., 2005)

brm[+]/brm² is an enhancer of macrochaeta phenotype of Delta²⁶⁶

(Armstrong et al., 2005)

brm[+]/brm² is an enhancer of ommatidium phenotype of Delta²⁶⁶

(Armstrong et al., 2005)

brm[+]/brm² is an enhancer of wing phenotype of ct^53d

(Krupp et al., 2005)

brm² is an enhancer of eye phenotype of H^UAS.cMa, Scer\GAL4^GMR.PF

(Müller et al., 2005)

brm² is an enhancer of wing vein L5 phenotype of rho^ve-1

(Marenda et al., 2004)

brm² is an enhancer of wing phenotype of tna¹

(Gutierrez et al., 2003)

brm² is an enhancer of wing phenotype of osa¹

(Gutierrez et al., 2003)

brm² is an enhancer of thorax phenotype of Chi^E

(Heitzler et al., 2003)

brm[+]/brm² is an enhancer of adult abdomen | somatic clone phenotype of Snr1^R3

(Zraly et al., 2003)

brm[+]/brm² is an enhancer of adult abdominal segment 4 | ectopic phenotype of E(z)^Trm

(Bajusz et al., 2001)

brm[+]/brm² is an enhancer of adult abdominal segment 5 phenotype of E(z)^Trm

(Bajusz et al., 2001)

brm[+]/brm² is an enhancer of adult mesothoracic segment | ectopic phenotype of E(z)^Trm

(Bajusz et al., 2001)

brm[+]/brm² is an enhancer of adult metathoracic segment phenotype of E(z)^Trm

(Bajusz et al., 2001)

brm[+]/brm² is an enhancer of adult prothoracic segment phenotype of E(z)^Trm

(Bajusz et al., 2001)

brm[+]/brm² is an enhancer of wing margin phenotype of Scer\GAL4^en-e16E, shg^UAS.cSa

(Barker et al., 2001)

brm[+]/brm² is an enhancer of wing blade posterior compartment phenotype of Scer\GAL4^en-e16E, shg^UAS.cSa

(Barker et al., 2001)

brm[+]/brm² is an enhancer of eye phenotype of Scer\GAL4^ey.PH, osa^UAS.cCa

(Collins et al., 1999)

trx[+], trx^E2, brm[+], brm² is an enhancer of arista phenotype of lawc^p1

(Zorin et al., 1999)

trx[+], trx^E2, brm[+], brm² is an enhancer of phenotype of mod(mdg4)^ul

(Gerasimova and Corces, 1998)

NOT Enhancer of

Statement

Reference

brm[+]/brm² is a non-enhancer of wing phenotype of E2f1^UAS.cNa, Scer\GAL4^Act88F.PD

(Ji et al., 2012)

brm[+]/brm² is a non-enhancer of eye phenotype of Dp^UAS.cDa, E2f1^UAS.cNa, Scer\GAL4^GMR.PU

(Ji et al., 2012)

brm[+]/brm² is a non-enhancer of phenotype of ct^2s

(Krupp et al., 2005)

brm[+]/brm² is a non-enhancer of phenotype of ct⁶

(Krupp et al., 2005)

brm[+]/brm² is a non-enhancer of triple row of wing sensilla phenotype of ct^K

(Krupp et al., 2005)

brm[+]/brm² is a non-enhancer of wing vein | ectopic phenotype of net¹

(Marenda et al., 2004)

brm[+]/brm² is a non-enhancer of haltere phenotype of Dsp1¹

(Decoville et al., 2001)

brm[+]/brm² is a non-enhancer of wing | ectopic phenotype of Dsp1¹

(Decoville et al., 2001)

brm² is a non-enhancer of eye phenotype of BEAF-32^UAS.cYa, Scer\GAL4^GMR.PS

(Yamaguchi et al., 2001)

Suppressor of

Statement

Reference

brm[+]/brm² is a suppressor of wing vein | adult stage phenotype of Marcal1^UAS.cBa, Scer\GAL4^Tub.PU

(Morimoto et al., 2016)

brm[+]/brm² is a suppressor of wing vein | adult stage phenotype of Hsap\SMARCAL1^UAS.cBa, Scer\GAL4^Bx-MS1096

(Morimoto et al., 2016)

brm² is a suppressor of intestinal stem cell of posterior adult midgut epithelium phenotype of Scer\GAL4^Tub.PU, yki^UAS.cZa

(Jin et al., 2013)

brm[+]/brm² is a suppressor of eye phenotype of E2f1^RNAi.UAS.cJa, Scer\GAL4^GMR.PU

(Ji et al., 2012)

brm[+]/brm² is a suppressor of first posterior wing cell phenotype of E2f1^RNAi.UAS.cJa, Scer\GAL4^ptc-559.1

(Ji et al., 2012)

brm[+]/brm² is a suppressor of wing vein | ectopic phenotype of Snr1^E1

(Curtis et al., 2011)

brm[+]/brm², Scer\GAL4^bbg-C96 is a suppressor | partially of wing margin phenotype of Raf^UAS.F179, Scer\GAL4^bbg-C96

(Herr et al., 2010)

brm[+]/brm² is a suppressor of eye phenotype of Egfr^E3

(Herr et al., 2010)

osa[+], brm[+], osa³⁰⁸, brm² is a suppressor of wing vein | ectopic phenotype of bs²

(Terriente-Félix and de Celis, 2009)

osa[+], brm[+], osa³⁰⁸, brm² is a suppressor of wing vein | ectopic phenotype of net¹, px⁷²

(Terriente-Félix and de Celis, 2009)

brm² is a suppressor of eye phenotype of Myc^UAS.cZa, Scer\GAL4^GMR.PF

(Secombe et al., 2007)

brm² is a suppressor of wing vein | ectopic phenotype of Snr1^E1

(Marenda et al., 2004)

brm² is a suppressor of wing vein | ectopic phenotype of bs⁰³²⁶⁷

(Marenda et al., 2004)

brm² is a suppressor of wing vein | ectopic phenotype of bs²

(Marenda et al., 2004)

brm² is a suppressor | partially of wing vein | ectopic phenotype of HDAC3^B, Snr1^R3/Snr1[+]

(Zraly et al., 2004)

brm² is a suppressor | partially of wing phenotype of HDAC3^B, Snr1^R3/Snr1[+]

(Zraly et al., 2004)

brm² is a suppressor | partially of wing vein | ectopic phenotype of HDAC1⁰⁴⁵⁵⁶, Snr1^R3/Snr1[+]

(Zraly et al., 2004)

brm² is a suppressor | partially of wing vein | ectopic phenotype of HDAC1⁰⁴⁵⁵⁶, Snr1^E1/Snr1[+]

(Zraly et al., 2004)

brm² is a suppressor | partially of wing phenotype of HDAC1⁰⁴⁵⁵⁶, Snr1^R3/Snr1[+]

(Zraly et al., 2004)

brm² is a suppressor | partially of wing phenotype of HDAC1⁰⁴⁵⁵⁶, Snr1^E1/Snr1[+]

(Zraly et al., 2004)

brm² is a suppressor of dorsocentral bristle phenotype of Chi^E

(Heitzler et al., 2003)

brm² is a suppressor of eye phenotype of CycE^JP

(Brumby et al., 2002)

brm² is a suppressor of wing vein L5 phenotype of CycE^JP

(Brumby et al., 2002)

brm² is a suppressor of wing phenotype of CycE^JP

(Brumby et al., 2002)

brm[+]/brm² is a suppressor of eye phenotype of Scer\GAL4^ey.PH, asf1^UAS.cMa

(Moshkin et al., 2002)

brm[+]/brm² is a suppressor of embryonic/larval hemocyte phenotype of hop^Tum

(Remillieux-Leschelle et al., 2002)

brm[+]/brm² is a suppressor of embryonic/larval hemocyte phenotype of mxc^G43

(Remillieux-Leschelle et al., 2002)

brm[+]/brm² is a suppressor of eye phenotype of arm^S56F.GMR

(Barker et al., 2001)

brm[+]/brm² is a suppressor of eye phenotype of Dref^UAS.cSa, Scer\GAL4^GMR.PS

(Hirose et al., 2001)

brm² is a suppressor of phenotype of Pc⁴

(Kennison and Tamkun, 1988)

NOT Suppressor of

Statement

Reference

brm[+]/brm² is a non-suppressor of eye phenotype of Dp^UAS.cDa, E2f1^UAS.cNa, Scer\GAL4^GMR.PU

(Ji et al., 2012)

brm[+]/brm² is a non-suppressor of wing phenotype of E2f1^UAS.cNa, Scer\GAL4^Act88F.PD

(Ji et al., 2012)

brm[+]/brm² is a non-suppressor of triple row of wing sensilla phenotype of ct^K

(Krupp et al., 2005)

brm[+]/brm² is a non-suppressor of phenotype of ct^2s

(Krupp et al., 2005)

brm[+]/brm² is a non-suppressor of phenotype of ct⁶

(Krupp et al., 2005)

brm[+]/brm² is a non-suppressor of wing vein | ectopic phenotype of net¹

(Marenda et al., 2004)

brm[+]/brm² is a non-suppressor of lamellocyte phenotype of hop^Tum

(Remillieux-Leschelle et al., 2002)

brm[+]/brm² is a non-suppressor of lamellocyte phenotype of Tl^10b

(Remillieux-Leschelle et al., 2002)

brm[+]/brm² is a non-suppressor of embryonic/larval hemocyte phenotype of Tl^10b

(Remillieux-Leschelle et al., 2002)

brm[+]/brm² is a non-suppressor of embryonic/larval plasmatocyte phenotype of Tl^10b

(Remillieux-Leschelle et al., 2002)

brm² is a non-suppressor of eye phenotype of BEAF-32^UAS.cYa, Scer\GAL4^GMR.PS

(Yamaguchi et al., 2001)

trx^E2/brm² is a non-suppressor of wing phenotype of Scer\GAL4^OK386, nej^UAS.cMa

(Bantignies et al., 2000)

Other

Statement

Reference

brm², sxc^H537A has scutellar bristle | ectopic phenotype

(Mariappa et al., 2018)

brm², sxc[+]/sxc^H537A has scutellar bristle | ectopic phenotype

(Mariappa et al., 2018)

brm[+]/brm², trx^E2 has metathoracic leg phenotype

(Rincon-Arano et al., 2012)

Su(var)3-3[+]/Su(var)3-3^ΔN, brm² has wing vein | ectopic phenotype

(Curtis et al., 2011)

γTub23C^Pl-2, brm² has wing phenotype

(Vázquez et al., 2008)

γTub23C^Pl-2, brm[+]/brm², osa¹/osa[+] has wing phenotype

(Vázquez et al., 2008)

Df(2R)ED3921, brm² has wing phenotype

(Ragab et al., 2006)

Egfr^f2, brm² has humeral bristle phenotype

(Armstrong et al., 2005)

Df(3L)ZN47/+, brm² has humeral bristle phenotype

(Armstrong et al., 2005)

Delta²³⁷¹/Dl[+], brm² has humeral bristle phenotype

(Armstrong et al., 2005)

Delta²⁶⁶/Dl[+], brm² has humeral bristle phenotype

(Armstrong et al., 2005)

Egfr[+]/Egfr^f2, brm² has humeral bristle phenotype

(Armstrong et al., 2005)

brm², vn[+]/vn¹⁰⁵⁶⁷ has humeral bristle phenotype

(Armstrong et al., 2005)

brm², vn[+]/vn⁶⁴³ has wing phenotype

(Armstrong et al., 2005)

brm², vn[+]/vn⁶⁴³ has humeral bristle phenotype

(Armstrong et al., 2005)

brm², vn[+]/vn^C221 has wing phenotype

(Armstrong et al., 2005)

Delta^9P/Dl[+], brm² has ommatidium phenotype

(Armstrong et al., 2005)

brm², mor[+]/mor⁴ has ommatidium phenotype

(Armstrong et al., 2005)

brm², mor[+]/mor⁴ has humeral bristle phenotype

(Armstrong et al., 2005)

brm², mor⁴ has ommatidium phenotype

(Armstrong et al., 2005)

brm², mor⁴ has humeral bristle phenotype

(Armstrong et al., 2005)

brm², vn¹⁰⁵⁶⁷ has humeral bristle phenotype

(Armstrong et al., 2005)

brm², vn^C221 has wing phenotype

(Armstrong et al., 2005)

brm², vn⁶⁴³ has wing phenotype

(Armstrong et al., 2005)

brm², vn⁶⁴³ has humeral bristle phenotype

(Armstrong et al., 2005)

Delta²³⁷¹, brm² has humeral bristle phenotype

(Armstrong et al., 2005)

Delta²⁶⁶, brm² has humeral bristle phenotype

(Armstrong et al., 2005)

Delta^9P, brm² has ommatidium phenotype

(Armstrong et al., 2005)

Scer\GAL4^en-e16E, brm[+]/brm², wg^UAS.cLa has ventral denticle belt phenotype

(Desbordes et al., 2005)

Scer\GAL4^en-e16E, brm[+]/brm², wg^UAS.cLa has embryonic/first instar larval cuticle phenotype

(Desbordes et al., 2005)

Scer\GAL4^en-e16E, brm², wg^UAS.cLa has ventral denticle belt phenotype

(Desbordes et al., 2005)

Scer\GAL4^en-e16E, brm², wg^UAS.cLa has embryonic/first instar larval cuticle phenotype

(Desbordes et al., 2005)

brm², trx[+]/trx^E2 has humeral bristle phenotype

(Möller et al., 2005)

Pc⁴, brm² has wing vein L3 phenotype

(Marenda et al., 2004)

Kr^If-1, brm[+]/brm² has eye phenotype

(Sollars et al., 2003)

Kr^If-1, brm² has eye phenotype

(Sollars et al., 2003)

brm[+]/brm², trx^E2 has adult abdominal segment 6 | male phenotype

(Zhang et al., 2003)

brm[+]/brm², trx^E2 has adult abdominal segment 5 | ectopic | male phenotype

(Zhang et al., 2003)

brm², trx[+]/trx^E2 has adult abdominal segment 6 | male phenotype

(Zhang et al., 2003)

brm², trx[+]/trx^E2 has adult abdominal segment 5 | ectopic | male phenotype

(Zhang et al., 2003)

brm², tara¹/tara[+] has wing phenotype

(Calgaro et al., 2002)

brm², tara¹/tara[+], trx[+]/trx^E2 has wing phenotype

(Calgaro et al., 2002)

brm², tara^L4/tara[+], trx[+]/trx^E2 has wing phenotype

(Calgaro et al., 2002)

brm², tara^L4/tara[+] has wing phenotype

(Calgaro et al., 2002)

brm², tara¹ has wing phenotype

(Calgaro et al., 2002)

brm[+]/brm², tara¹, trx[+]/trx^E2 has wing phenotype

(Calgaro et al., 2002)

brm², tara^L4 has wing phenotype

(Calgaro et al., 2002)

brm², trx^E2 has wing phenotype

(Calgaro et al., 2002)

brm[+]/brm², tara¹/tara[+], trx^E2 has wing phenotype

(Calgaro et al., 2002)

brm[+]/brm², tara^L4/tara[+], trx^E2 has wing phenotype

(Calgaro et al., 2002)

brm², trx[+]/trx^E2 has wing phenotype

(Calgaro et al., 2002)

Asx¹³, brm² has adult metathoracic segment phenotype

(Gildea et al., 2000)

E(Pc)¹, brm² has adult metathoracic segment phenotype

(Gildea et al., 2000)

Asx³/Asx[+], brm² has adult metathoracic segment phenotype

(Gildea et al., 2000)

Asx^XF23/Asx[+], brm² has adult metathoracic segment phenotype

(Gildea et al., 2000)

+/Df(2L)Mdh, brm² has adult metathoracic segment phenotype

(Gildea et al., 2000)

Df(2L)cl-h3/+, brm² has adult metathoracic segment phenotype

(Gildea et al., 2000)

Df(2R)Pu-D17/+, brm² has adult metathoracic segment phenotype

(Gildea et al., 2000)

Df(2R)or-BR6/+, brm² has adult metathoracic segment phenotype

(Gildea et al., 2000)

Df(3L)Ar14-8/+, brm² has adult metathoracic segment phenotype

(Gildea et al., 2000)

E(Pc)[+]/E(Pc)¹, brm² has adult metathoracic segment phenotype

(Gildea et al., 2000)

Psc[+]/Psc¹, brm² has adult metathoracic segment phenotype

(Gildea et al., 2000)

Sce[+]/Sce^D1, brm² has adult metathoracic segment phenotype

(Gildea et al., 2000)

Su(z)2¹/Su(z)2[+], brm² has adult metathoracic segment phenotype

(Gildea et al., 2000)

Su(z)6[+]/Su(z)6¹, brm² has adult metathoracic segment phenotype

(Gildea et al., 2000)

Su(z)7[+]/Su(z)7¹, brm² has adult metathoracic segment phenotype

(Gildea et al., 2000)

Trl[+]/Trl^R85, brm² has adult metathoracic segment phenotype

(Gildea et al., 2000)

Kdm5^k06801/lid[+], brm² has adult metathoracic segment phenotype

(Gildea et al., 2000)

Psc¹, brm² has adult metathoracic segment phenotype

(Gildea et al., 2000)

Kdm5^k06801, brm² has adult metathoracic segment phenotype

(Gildea et al., 2000)

Sce^D1, brm² has adult metathoracic segment phenotype

(Gildea et al., 2000)

Sce^D1, brm[+]/brm² has metathoracic leg phenotype

(Gildea et al., 2000)

Sce^D1, brm[+]/brm² has mesothoracic tibial apical bristle | ectopic phenotype

(Gildea et al., 2000)

Sce^D1, brm[+]/brm², trx[+]/trx² has metathoracic leg phenotype

(Gildea et al., 2000)

Sce^D1, brm[+]/brm², trx[+]/trx² has mesothoracic tibial apical bristle | ectopic phenotype

(Gildea et al., 2000)

Sce^D1, brm[+]/brm², trx[+]/trx² has mesothoracic tibial preapical bristle | ectopic phenotype

(Gildea et al., 2000)

Sce^D1, brm[+]/brm², trx[+]/trx² has sternopleural bristle | ectopic phenotype

(Gildea et al., 2000)

Su(z)2¹, brm² has adult metathoracic segment phenotype

(Gildea et al., 2000)

Asx^XF23, brm² has adult metathoracic segment phenotype

(Gildea et al., 2000)

Su(z)6¹, brm² has adult metathoracic segment phenotype

(Gildea et al., 2000)

Su(z)7¹, brm² has adult metathoracic segment phenotype

(Gildea et al., 2000)

Trl^R85, brm² has adult metathoracic segment phenotype

(Gildea et al., 2000)

Asx³, brm² has adult metathoracic segment phenotype

(Gildea et al., 2000)

Sce^D1, brm² has metathoracic leg phenotype

(Gildea et al., 2000)

Sce^D1, brm² has mesothoracic tibial apical bristle | ectopic phenotype

(Gildea et al., 2000)

Asx[+]/Asx¹³, brm² has adult metathoracic segment phenotype

(Gildea et al., 2000)

ash1⁶, brm² has adult abdominal segment 5 phenotype

(Vazquez et al., 1999)

brm², trx^E2 has adult abdominal segment 5 phenotype

(Vazquez et al., 1999)

brm², osa¹¹ has wing phenotype

(Vazquez et al., 1999)

brm², osa¹ has wing phenotype

(Vazquez et al., 1999)

brm², osa² has wing phenotype

(Vazquez et al., 1999)

brm², osa¹² has wing phenotype

(Vazquez et al., 1999)

brm², mor¹ has wing phenotype

(Vazquez et al., 1999)

brm², mor² has wing phenotype

(Vazquez et al., 1999)

brm², trx^E2 has metathoracic leg phenotype

(Zorin et al., 1999)

brm², trx^E2 has haltere phenotype

(Zorin et al., 1999)

ash1^unspecified, brm[+]/brm² has metathoracic leg phenotype

(Tripoulas et al., 1996)

ash1^unspecified, brm[+]/brm² has haltere phenotype

(Tripoulas et al., 1996)

ash1^unspecified/ash1[+], brm² has metathoracic leg phenotype

(Tripoulas et al., 1996)

ash1^unspecified/ash1[+], brm² has haltere phenotype

(Tripoulas et al., 1996)

Snr1^R3/Snr1[+], brm² has postpronotum phenotype

(Dingwall et al., 1995)

Snr1^R3/Snr1[+], brm² has adult prothoracic segment phenotype

(Dingwall et al., 1995)

Snr1^R3, brm² has postpronotum phenotype

(Dingwall et al., 1995)

ash1¹, brm[+]/brm² has scutellum phenotype

(Tripoulas et al., 1994)

ash1¹, brm[+]/brm² has metathoracic leg phenotype

(Tripoulas et al., 1994)

ash1¹, brm[+]/brm² has haltere phenotype

(Tripoulas et al., 1994)

ash1¹, brm[+]/brm² has prothoracic leg phenotype

(Tripoulas et al., 1994)

ash1²⁸, brm[+]/brm² has scutellum phenotype

(Tripoulas et al., 1994)

ash1²⁸, brm[+]/brm² has metathoracic leg phenotype

(Tripoulas et al., 1994)

ash1²⁸, brm[+]/brm² has haltere phenotype

(Tripoulas et al., 1994)

ash1²⁸, brm[+]/brm² has prothoracic leg phenotype

(Tripoulas et al., 1994)

ash1⁶, brm[+]/brm² has scutellum phenotype

(Tripoulas et al., 1994)

ash1⁶, brm[+]/brm² has metathoracic leg phenotype

(Tripoulas et al., 1994)

ash1⁶, brm[+]/brm² has haltere phenotype

(Tripoulas et al., 1994)

ash1⁶, brm[+]/brm² has prothoracic leg phenotype

(Tripoulas et al., 1994)

ash1[+]/ash1¹, brm² has scutellum phenotype

(Tripoulas et al., 1994)

ash1[+]/ash1¹, brm² has metathoracic leg phenotype

(Tripoulas et al., 1994)

ash1[+]/ash1¹, brm² has haltere phenotype

(Tripoulas et al., 1994)

ash1[+]/ash1¹, brm² has prothoracic leg phenotype

(Tripoulas et al., 1994)

ash1[+]/ash1⁶, brm² has scutellum phenotype

(Tripoulas et al., 1994)

ash1[+]/ash1⁶, brm² has metathoracic leg phenotype

(Tripoulas et al., 1994)

ash1[+]/ash1⁶, brm² has haltere phenotype

(Tripoulas et al., 1994)

ash1[+]/ash1⁶, brm² has prothoracic leg phenotype

(Tripoulas et al., 1994)

ash1²⁸/ash1[+], brm² has scutellum phenotype

(Tripoulas et al., 1994)

ash1²⁸/ash1[+], brm² has metathoracic leg phenotype

(Tripoulas et al., 1994)

ash1²⁸/ash1[+], brm² has haltere phenotype

(Tripoulas et al., 1994)

ash1²⁸/ash1[+], brm² has prothoracic leg phenotype

(Tripoulas et al., 1994)

brm², trx[+]/trx^E2 has abdominal segment 5 phenotype

(Tamkun et al., 1992)

Additional Comments

Genetic Interactions

Statement

Reference

sxc^H537A/+, brm²/+ individuals and sxc^H537A/sxc^H537A, brm²/+ individuals show a minor ectopic scutellar bristle phenotype, as compared to controls.

(Mariappa et al., 2018)

Flies heterozygous for both Rel^E20 and brm² show a significant decrease in survival following Erwinia carotovora Ecc15 infection.

(Bonnay et al., 2014)

One copy of brm² enhances the supernumerary neuroblast phenotype seen in brat^DG19310/brat¹¹ mutants.

One copy of brm² enhances the supernumerary neuroblast phenotype seen in numb^NP2301 mutant larval brains.

(Janssens et al., 2014)

One copy of brm² enhances the scalloped wing phenotype seen in sd¹ mutant males.

brm² completely suppresses the significant increase in cell numbers seen in intestinal stem cell clones overexpressing of yki^Scer\UAS.cZa under the control of Scer\GAL4^esg-NP5130.

(Jin et al., 2013)

12% of Trl^R85/brm² double heterozygous adult males show transformation of A6 to A5.

(Nakayama et al., 2012)

56% of brm² trx^E2 double heterozygotes have an apical bristle on the third leg (usually found on the second leg). Heterozygosity for either upSET^e00365 or upSET^MB08950 reduces the penetrance of this phenotype to 9% or 4% respectively.

(Rincon-Arano et al., 2012)

Su(var)3-3^ΔN brm² double heterozygotes can have ectopic wing vein material distal to the posterior crossvein.

(Curtis et al., 2011)

brm²/+ significantly suppresses the notched wing phenotype resulting from the expression of phl^{Scer\UAS.F179} via Scer\GAL4^bbg-C96.

The small rough eye phenotype of Egfr^E3/+ is suppressed by brm²/+.

(Herr et al., 2010)

The ectopic wing vein phenotype observed in homozygous bs² mutant wings is suppressed in animals doubly heterozygous for osa³⁰⁸ and brm².

net¹, px⁷² double mutants develop ectopic wing veins in the L2/L3 and L4/L5 intervein regions. This phenotype is suppressed in flies double heterozygous for osa³⁰⁸ and brm².

(Terriente-Félix and de Celis, 2009)

brm² acts as strong dominant enhancer of the penetrance of the e(y)3⁴/Y bent-leg phenotype in male flies.

(Chalkley et al., 2008)

The low-penetrance "held-out" wing phenotype of brm²/+ adults is enhanced in a pont^5.1/+ background. Held-out wings are observed in 15% of double-heterozygous animals compared to 1.4% in brm²/+ mutants. Co-expression of pont^Scer\UAS.cDa under the control of Scer\GAL4^arm.PS in brm²/pont^5.1 animals reduces the penetrance of the wing phenotype to 1.7%.

The low-penetrance "held-out" wing phenotype of brm²/+ adults is suppressed in a rept³⁵/+ background. Held-out wings are observed in 0.6% of double-heterozygous animals compared to 1.4% in brm²/+ mutants. Co-expression of rept^Scer\UAS.cDa under the control of Scer\GAL4^arm.PS in brm²/rept³⁵ animals completely rescues the wing phenotype.

Triple-heterozygous brm², pont^5.1, and rept³⁵ mutant adults have a "held-out" wing phenotype at a low penetrance (2.1%), quite similar to the penetrance observed in brm²/+ animals.

The wings of brm²/+ animals expressing pont^{D302N.Scer\UAS} under the control of Scer\GAL4^arm.PS display a "held-out" phenotype in 35.5% of animals, much enhanced compared to brm²/+.

(Diop et al., 2008)

γTub23C^Pl-2 results in a held-out wing phenotype in double heterozygous combination with brm² (76% penetrance).

γTub23C^Pl-2/+ ; brm²/osa¹ triple heterozygous flies show poor survival and have twisted and blistered wings.

The reduced viability of γTub23C^A14-9/γTub23C^A6-2, γTub23C^A14-9/γTub23C^A15-2 and γTub23C^A14-9/Df(2L)3G flies is not further reduced by brm²/+.

(Vázquez et al., 2008)

Df(2R)ED3921; brm²/+ flies show an enhancement of the loss of vein L5 seen in Df(2R)ED3921 single mutants and a new held out wing phenotype not observed in either single mutant.

(Ragab et al., 2006)

The penetrance of the loss of humeral bristle phenotype seen in brm²/+ flies is increased by Bap60¹/+ from 7% to 14%.

5% of brm² trx^E2 double heterozygotes show loss of humeral bristles. The penetrance of this phenotype is increased to 15% by Bap60¹/+.

(Möller et al., 2005)

Pc⁴/brm² animals have an incomplete L3 wing vein (15%). brm² enhances the loss of wing vein L5 seen in rho^ve-1 homozygotes. Snr1^E1 suppresses the shortened L5 wing vein that results from the interaction between rho^ve-1 and brm².

(Marenda et al., 2004)

Rpd3⁰⁴⁵⁵⁶/brm² double heterozygotes have a normal wing phenotype. The ectopic wing vein phenotype seen in Rpd3⁰⁴⁵⁵⁶/Snr1^R3, Rpd3⁰⁴⁵⁵⁶/Snr1^E1 and Hdac3^N/Snr1^E1 double heterozygotes at 29^oC is partially suppressed by brm²/+.

(Zraly et al., 2004)

100% of brm²/tna¹ flies have a held-out wings phenotype. brm²/tna^S058302 flies do not have a held-out wings phenotype. 23% of brm²/tara² flies have a held-out wings phenotype. 8% of brm²/tara²⁰ flies have a held-out wings phenotype. 60% of brm²/tna^S058302 tara² flies have a held-out wings phenotype. 75% of brm²/tna^S058302 tara²⁰ flies have a held-out wings phenotype. Less than 1% of brm²/tara⁰³⁸⁸¹ flies have a held-out wings phenotype. 30% of brm²/tna^S058302 tara⁰³⁸⁸¹ flies have a held-out wings phenotype. 100% of brm²/osa¹ flies have a held-out wings phenotype.

(Gutierrez et al., 2003)

5+/-1% of Kr^If-1/+ flies born to brm²/+ mothers have outgrowths with ectopic vibrissae protruding from the ventral region of the eye, compared to less than 0.1% of Kr^If-1/+ flies born to isogenised wild-type mothers.

(Sollars et al., 2003)

brm² trx^E2 double heterozygous males show a low frequency of A6 to A5 transformation; the frequency is 9% if brm² trx^E2 is maternally derived and 17% if brm² trx^E2 is paternally derived. The frequency of A6 to A5 transformation seen in brm² trx^E2 double heterozygous males is increased if they also carry JIL-1^z2; the frequency is 65% if JIL-1^z2 is maternally derived and brm² trx^E2 is paternally derived and is 75% in the reciprocal cross.

(Zhang et al., 2003)

Homozygous Snr1^R3 clones induced in a brm²/+ background are less frequently observed and are smaller in size compared to both brm⁺ and control clones induced at similar stages, suggesting an additive effect between brm and Snr1. The presence of brm²/+ enhances the Snr1^R3 clone phenotype in the abdomen.

(Zraly et al., 2003)

Suppresses the CycE^JP rough eye phenotype.

(Brumby et al., 2002)

12% of brm² tara^L4 double heterozygotes have a held-out wing phenotype. 10% of brm² tara¹ double heterozygotes have a held-out wing phenotype. 5% of trx^E2 brm² double heterozygotes have a held-out wing phenotype. 45% of trx^E2 brm² tara^L4 triple heterozygotes have a held-out wing phenotype. 38% of trx^E2 brm² tara¹ triple heterozygotes have a held-out wing phenotype.

(Calgaro et al., 2002)

brm²/+ suppresses the rough eye phenotype due to Scer\GAL4^ey.PH; asf1^Scer\UAS.cMa.

(Moshkin et al., 2002)

The increased concentration of circulating hemocytes seen in mxc^G43 larvae is suppressed by brm²/+. The increased concentration of circulating hemocytes seen in hop^Tum larvae is significantly reduced by brm²/+, although lamellocyte ratios remain unchanged in the double mutants.

(Remillieux-Leschelle et al., 2002)

brm²/+ does not significantly enhance the frequency of transformation of halteres into wings seen in Dsp1¹/Y flies.

(Decoville et al., 2001)

A brm²/+, background significantly suppresses the rough eye phenotype found in flies expressing Dref^Scer\UAS.cSa under the control of Scer\GAL4^GMR.PS.

(Hirose et al., 2001)

The abdominal segment A6 to A5 transformation and the haltere to wing transformation of brm²/+, trx^E2/+ is dominantly suppressed by dom¹⁴.

(Ruhf et al., 2001)

Sce^D1/+ ; brm²/+ flies can show minimal transformation of the third leg to second leg; the third leg can have an apical bristle but does not have sternopleural bristles (both characteristics of the wild-type second leg). Sce^D1/+ ; brm² trx²/+ triple heterozygotes show transformations of third leg to second leg, having both apical and preapical bristles on the distal tibia of the third leg (which are characteristic of the wild-type second leg). The third leg may also have sternopleural bristles (characteristics of the wild-type second leg). Double heterozygotes with Df(2L)Mdh, Df(2R)or-BR6, Df(3L)Ar14-8, Df(2L)cl-h3, Df(2R)Pu-D17, lid^k06801, E(Pc)¹, Su(z)2¹, Psc¹, Trl^R85, Su(z)7¹, Su(z)6¹, Asx^XF23, Asx³ or Asx¹³ show T3 to T2 transformations. 35.3% of trx^E2 brm² double heterozygotes show T3 to T2 transformations. The penetrance of this phenotype is enhanced by one copy of lid^k06801, sxc¹, Sce^D1, E(z)⁵, Trl^R85, Su(z)4¹, Su(z)7¹, Su(z)6¹, E(Pc)¹, Su(z)2¹, Su(z)2^Arp1, Psc¹, Asx³ or Asx¹³ and suppressed by one copy of Pc³, ph-d⁵⁰³, Pcl⁷, pho^b, mxc^M1, mxc¹, esc⁹, esc¹⁰, esc²¹, sxc⁴ or M(2)21AB¹.

(Gildea et al., 2000)

Mutant heterozygotes show a strong enhancement of the eye phenotype seen in P{UAS-lacZ.Abd-B.5F24}, leading to lighter eyes.

(Cavalli, 1999)

The addition of brm² enhances the variable eye size phenotype seen in osa^Scer\UAS.cCa/Scer\GAL4^ey.PH flies.

(Collins et al., 1999)

Enhances the phenotype of E2f^GMR.PD Dp^GMR.PD BacA\p35^GMR.PH flies.

(Staehling-Hampton et al., 1999)

brm² osa² double heterozygotes have held-out wings in 97% of cases, a phenotype which is rarely seen in either single heterozygote. brm² osa¹¹ double heterozygotes have held-out wings in 35% of cases, a phenotype which is rarely seen in either single heterozygote. brm² osa¹² double heterozygotes have held-out wings. brm² osa¹ double heterozygotes have held-out wings. This phenotype is partially suppressed if the flies are also carrying brm^+t14.4. brm² shows little if any interaction in double heterozygous combination with Trl⁶², Trl³, Snr1⁰¹³¹⁹, skd², skd³, btl^dev1, btl^dev2, Vha55¹⁶, kto³, kis¹ or kis²; less than 3% of flies have held-out wings. brm² shows some interaction in double heterozygous combination with mor¹ or mor²; slightly more than 20% of flies have held-out wings. brm² trx^E2 and brm² ash1⁶ double heterozygotes show partial transformation of the 5th abdominal segment to fourth abdominal segment, but do not hold out their wings at any significantly higher frequency than that seen in brm²/+ single heterozygotes.

(Vazquez et al., 1999)

The frequency of homeotic transformations in heterozygotes is not enhanced by lawc^p1, lawc^EF520, lawc⁺¹⁰ or Df(1)RA2. The frequency and severity of homeotic transformations (such as haltere to wing or third leg to second leg transformations) in brm² trx^E2 double heterozygotes is dominantly enhanced by lawc^p1. The enhancement is stronger in a lawc^p1 maternal background. The arista to leg transformation characteristic of lawc^p1 is also enhanced in these flies. The frequency of homeotic transformations in brm² trx^E2 double heterozygotes is dominantly enhanced by lawc^EF520 or Df(1)RA2. lawc^p1/lawc^EF520 females are viable. However, in combination with brm², lawc^p1/lawc^EF520 results in lethality. lawc^p1/Df(1)RA2 females are viable. However, in combination with brm², lawc^p1/Df(1)RA2 results in lethality.

(Zorin et al., 1999)

10.0% of trx^E2 brm² double heterozygous adults show a homeotic phenotype. This is increased to 56.5% if the flies are also heterozygous for mod(mdg4)^T16, 24.9% if the flies are also heterozygous for mod(mdg4)^ul and 35.7% if the flies are also heterozygous for mod(mdg4)^T6. The combination brm² trx^E2 dominantly enhances the effect of mod(mdg4)^ul on the y² phenotype.

(Gerasimova and Corces, 1998)

The lethality caused by sev^{S11.T:Hsap\MYC} in combination with Ras85D^V12.sev is suppressed by brm².

(Maixner et al., 1998)

Double heterozygotes with ash1 mutations exhibit transformation of third leg to second leg identity and haltere to wing transformation.

(Tripoulas et al., 1996)

Snr1^R3/brm² transheterozygous adults display prothoracic defects, including loss of the humerus.

(Dingwall et al., 1995)

Heterozygotes of ash1¹, ash1⁶, and ash1²⁸ with brm² have homeotic transformations of the third to the second leg. The expressivity of the transformed leg is variable, some have only a second leg apical bristle while others have a second leg preapical bristle as well. There is a lower penetrance of third leg transformations among flies heterozygous for ash1¹, ash1⁶, and ash1²⁸ with brm⁵. Degree of penetrance corresponds to the severity of the ash1 allele (ash1¹ < ash1⁶ < ash1²⁸). There is a lower penetrance of partial homeotic transformation of the haltere to the wing, or dorsal metathoracic cuticle to mesothoracic cuticle, and an even lower penetrance of first leg to second leg transformations.

(Tripoulas et al., 1994)

Suppresses all Pc leg transformations and Pcl second and third leg to first leg transformations. trx^E2, brm² double heterozygotes frequently display homeotic transformations: fifth abdominal segment is transformed to a more anterior identity and haltere to wing.

(Tamkun et al., 1992)

Suppresses the extra sex comb phenotype of Pc⁴, Ts(YLt;2Lt)L124. Causes between 50% and 100% suppression of the Pc⁴/+ extra sex combs phenotype.

(Kennison and Tamkun, 1988)

Xenogenetic Interactions

Statement

Reference

The formation of ectopic wing veins observed in adult flies expressing Hsap\SMARCAL1^Scer\UAS.cBa under the control of Scer\GAL4^Bx-MS1096 is ameliorated by combination with a single copy of brm².

(Morimoto et al., 2016)

Complementation and Rescue Data

Fails to complement

brm^ksh-6

(Staehling-Hampton et al., 1999)

brm^ksh-7

(Staehling-Hampton et al., 1999)

brm^ksh-8

(Staehling-Hampton et al., 1999)

brm^pjc-2

(Staehling-Hampton et al., 1999)

Rescued by

Df(3L)th102/brm² is rescued by brm^Δ1446-1517

(Elfring et al., 1998)

brm² is rescued by brm^+t14.4

(Elfring et al., 1998)

Not rescued by

Df(3L)th102/brm² is not rescued by brm^{Δ549-610.Tag:HA,Tag:polyHis}

(Elfring et al., 1998)

Df(3L)th102/brm² is not rescued by brm^{K804R.Tag:HA,Tag:polyHis}

(Elfring et al., 1998)

Comments

The mechanosensory bristle phenotypes are rescued if the clones are carrying brm^+t14.4. Homozygous and hemizygous lethality is rescued by brm^+t14.4. Hemizygous lethality is rescued by brm^Δ1446-1517. brm²/Df(3L)th102 animals carrying two copies of brm^{K804R.T:Ivir\HA1} do not survive to adulthood.

(Elfring et al., 1998)

Images (0)

Mutant

Wild-type

Stocks (4)

Bloomington

3622

brm² trx^E2 ca¹/TM6B, Tb⁺ ca¹

3619

brm² e^s ca¹/TM6B, Sb¹ Tb¹ ca¹

Kyoto

107135

brm² trx^E2 ca¹/TM6B, Tb¹ ca¹

107133

brm² e^s ca¹/TM6B, Sb¹ Tb¹ ca¹

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (4)

Reported As

Symbol Synonym

Brm²

(Secombe et al., 2007, Cavalli, 1999)

brm^-

(Tea and Luo, 2011)

brm²

(Bala et al., 2026, Bi et al., 2022, Ponrathnam et al., 2021, Tian and Smith-Bolton, 2021, Carnesecchi et al., 2020, Leatham-Jensen et al., 2019, Mariappa et al., 2018, Hong and Choi, 2016, Singh and Mishra, 2015, Janssens et al., 2014, Bengani et al., 2013, Jin et al., 2013, Vasanthi et al., 2013, Ji et al., 2012, Nakayama et al., 2012, Nowak et al., 2012, Popkova et al., 2012, Rincon-Arano et al., 2012, Tie et al., 2012, Curtis et al., 2011, Di Stefano et al., 2011, Kirilly et al., 2011, Pérez et al., 2011, Sultana et al., 2011, Tea and Luo, 2011, Arancio et al., 2010, Bhatia et al., 2010, Herr et al., 2010, Lamiable et al., 2010, Smulders-Srinivasan et al., 2010, Christensen et al., 2009.5.6, Cook et al., 2009.11.25, Terriente-Félix and de Celis, 2009, Carrera et al., 2008, Chalkley et al., 2008, Chen et al., 2008, Christensen et al., 2008.4.15, Christensen et al., 2008.7.11, Diop et al., 2008, Hallson et al., 2008, Remaud et al., 2008, Vázquez et al., 2008, Chang et al., 2007, Möller et al., 2005, Hirose et al., 2001)

Name Synonyms

brahma2

(Bonnay et al., 2014)

Secondary FlyBase IDs

References (110)

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