FlyBase Allele Report: Dmel\tna[S058302]

General Information

Symbol

Dmel\tna^S058302

Species

D. melanogaster

Name

FlyBase ID

FBal0100065

Feature type

allele

Associated gene

Dmel\tna

Associated Insertion(s)

P{lacW}tna^S058302

Carried in Construct

Key Links

Genomic Maps

JBrowse

Allele class

Mutagen

Nature of the Allele

Allele class

Mutagen

Delta2-3 transposase

(Deak et al., 1997)

P-element activity

(Szeged Stock Center, 1998-)

Progenitor genotype

Associated Insertion(s)

P{lacW}tna^S058302

Cytology

Description

P{lacW} insertion within the first large intron of tna.

(Gutierrez et al., 2003)

Allele components

Component

Use(s)

Inserted element

P{lacW}

enhancer trap

Encoded product / tool

lacZ

reporter enzyme

Tagged with

Tag:NLS(P)

nuclear protein localization tag

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

transposable_element_insertion_site

3L:10,863,074..10,866,313 [+]

(Gutierrez et al., 2003, Szeged Stock Center, 1998-, Deak et al., 1997)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

haltere (with tna¹)

(Gutierrez et al., 2003)

sex comb (with tna¹)

(Gutierrez et al., 2003)

sex comb (with tna^L6731)

(Gutierrez et al., 2003)

sex comb (with tna^rI075)

(Gutierrez et al., 2003)

wing | ectopic (with tna¹)

(Gutierrez et al., 2003)

Detailed Description

Statement

Reference

Heterozygotes do not have a held-out wings phenotype. tna¹/tna^S058302, tna^rI075/tna^S058302 and tna^L6731/tna^S058302 flies show a reduction in the number of sex combs on the first leg. tna¹/tna^S058302 flies can have a partial transformation of haltere to wing. tna^S058302/Df(3L)lxd6 animals dervied from tna^S058302 homozygous female germline clones (these animals lack both maternal and zygotic tna function) generally die as third instar larvae. tna^S058302/+ animals derived from tna^S058302 homozygous female germline clones (these animals lack maternal but not zygotic tna function) develop to normal, fertile adults.

(Gutierrez et al., 2003)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhancer of

Statement

Reference

tna^S058302/tara⁰³⁸⁸¹ is an enhancer of visible | dominant phenotype of brm²

(Gutierrez et al., 2003)

tna^S058302/tara²⁰ is an enhancer of visible | dominant phenotype of brm²

(Gutierrez et al., 2003)

tna^S058302/tara² is an enhancer of visible | dominant phenotype of brm²

(Gutierrez et al., 2003)

NOT Enhancer of

Statement

Reference

tna^S058302 is a non-enhancer of visible | dominant phenotype of osa¹

(Gutierrez et al., 2003)

tna^S058302 is a non-enhancer of visible | dominant phenotype of brm²

(Gutierrez et al., 2003)

Suppressor of

Statement

Reference

tna^S058302 is a suppressor of visible | dominant phenotype of Pc³

(Gutierrez et al., 2003)

tna^S058302 is a suppressor of visible | dominant phenotype of Scr^Msc

(Gutierrez et al., 2003)

Phenotype Manifest In

Enhancer of

Statement

Reference

tna^S058302/tara⁰³⁸⁸¹ is an enhancer of wing phenotype of brm²

(Gutierrez et al., 2003)

tna^S058302/tara²⁰ is an enhancer of wing phenotype of brm²

(Gutierrez et al., 2003)

tna^S058302/tara² is an enhancer of wing phenotype of brm²

(Gutierrez et al., 2003)

NOT Enhancer of

Statement

Reference

tna^S058302 is a non-enhancer of wing phenotype of osa¹

(Gutierrez et al., 2003)

tna^S058302 is a non-enhancer of wing phenotype of brm²

(Gutierrez et al., 2003)

Suppressor of

Statement

Reference

tna^S058302 is a suppressor of mesothoracic leg phenotype of Pc³

(Gutierrez et al., 2003)

tna^S058302 is a suppressor of metathoracic leg phenotype of Pc³

(Gutierrez et al., 2003)

tna^S058302 is a suppressor of sex comb | ectopic phenotype of Pc³

(Gutierrez et al., 2003)

tna^S058302 is a suppressor of mesothoracic leg phenotype of Scr^Msc

(Gutierrez et al., 2003)

tna^S058302 is a suppressor of metathoracic leg phenotype of Scr^Msc

(Gutierrez et al., 2003)

tna^S058302 is a suppressor of sex comb | ectopic phenotype of Scr^Msc

(Gutierrez et al., 2003)

Additional Comments

Genetic Interactions

Statement

Reference

brm²/tna^S058302 flies do not have a held-out wings phenotype. 60% of brm²/tna^S058302 tara² flies have a held-out wings phenotype. 75% of brm²/tna^S058302 tara²⁰ flies have a held-out wings phenotype. 30% of brm²/tna^S058302 tara⁰³⁸⁸¹ flies have a held-out wings phenotype. tna^S058302/osa¹ flies do not have a held-out wings phenotype. tna^S058302/tara⁰³⁸⁸¹ flies do not have a held-out wings phenotype.

(Gutierrez et al., 2003)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Fails to complement

tna¹

(Gutierrez et al., 2003)

tna^L6731

(Gutierrez et al., 2003)

tna^rI075

(Gutierrez et al., 2003)

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (4)

Reported As

Symbol Synonym

0583/02

(Deak et al., 1997)

l(3)S058302^S058302

tna³

(Gutierrez et al., 2003)

tna^S058302

Name Synonyms

Secondary FlyBase IDs

References (3)

Report Sections

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