FlyBase Allele Report: Dmel\tara[03881]

General Information

Symbol

Dmel\tara⁰³⁸⁸¹

Species

D. melanogaster

Name

FlyBase ID

FBal0009493

Feature type

allele

Associated gene

Dmel\tara

Associated Insertion(s)

P{PZ}tara⁰³⁸⁸¹

Carried in Construct

Also Known As

tara-lacZ

Key Links

Allele class

Mutagen

P-element activity

Nature of the Allele

Allele class

Mutagen

P-element activity

Progenitor genotype

Associated Insertion(s)

P{PZ}tara⁰³⁸⁸¹

Cytology

Description

Allele components

Component

Use(s)

Inserted element

P{PZ}

enhancer trap

Encoded product / tool

lacZ

reporter enzyme

Tagged with

Tag:NLS(P)

nuclear protein localization tag

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

homeotic | embryonic stage

(Dutta and Li, 2017)

increased cell number | embryonic stage

(Dutta and Li, 2017)

lethal | recessive

(Spradling et al., 1999, BDGP Project Members, 1994-1999)

lethal - all die during embryonic stage

(Dutta and Li, 2017)

visible | dominant

(Gutierrez et al., 2003)

visible | embryonic stage

(Dutta and Li, 2017)

Phenotype Manifest In

ventral denticle belt | embryonic stage

(Dutta and Li, 2017)

wing

(Gutierrez et al., 2003)

Detailed Description

Statement

Reference

Denticle belts of tara⁰³⁸⁸¹ homozygous embryos exhibit homeotic transformation mostly in the posterior segment: the abdominal segments A6 and A7 are transformed into A8.

tara⁰³⁸⁸¹ homozygotes exhibit an increased number of cells expressing engrailed in a stripe during embryonic development at germ-band extension.

(Dutta and Li, 2017)

5% of heterozygous flies have a held-out wings phenotype.

(Gutierrez et al., 2003)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhanced by

Statement

Reference

tara⁰³⁸⁸¹ has increased cell number | embryonic stage phenotype, enhanceable by Pc³/Pc³

(Dutta and Li, 2017)

tara⁰³⁸⁸¹ has visible | dominant phenotype, enhanceable by tna¹

(Gutierrez et al., 2003)

tara⁰³⁸⁸¹ has visible | dominant phenotype, enhanceable by osa¹

(Gutierrez et al., 2003)

NOT Enhanced by

Statement

Reference

tara⁰³⁸⁸¹ has visible | embryonic stage phenotype, non-enhanceable by Pc³/Pc³

(Dutta and Li, 2017)

tara⁰³⁸⁸¹ has homeotic | embryonic stage phenotype, non-enhanceable by Pc³/Pc³

(Dutta and Li, 2017)

NOT suppressed by

Statement

Reference

tara⁰³⁸⁸¹ has visible | embryonic stage phenotype, non-suppressible by Pc³/Pc³

(Dutta and Li, 2017)

tara⁰³⁸⁸¹ has homeotic | embryonic stage phenotype, non-suppressible by Pc³/Pc³

(Dutta and Li, 2017)

Enhancer of

Statement

Reference

tara⁰³⁸⁸¹/tara⁰³⁸⁸¹ is an enhancer of increased cell number | embryonic stage phenotype of Pc³

(Dutta and Li, 2017)

tara⁰³⁸⁸¹ is an enhancer of homeotic phenotype of Ubx^1:Cbx-1

(Dutta and Li, 2017)

tara⁰³⁸⁸¹ is an enhancer of visible phenotype of Ubx^1:Cbx-1

(Dutta and Li, 2017)

tara⁰³⁸⁸¹/tara[+] is an enhancer of visible | dominant phenotype of Bx¹

(Bejarano et al., 2008)

tara⁰³⁸⁸¹ is an enhancer of visible | dominant phenotype of tna¹

(Gutierrez et al., 2003)

tara⁰³⁸⁸¹ is an enhancer of visible | dominant phenotype of osa¹

(Gutierrez et al., 2003)

tna^S058302/tara⁰³⁸⁸¹ is an enhancer of visible | dominant phenotype of brm²

(Gutierrez et al., 2003)

NOT Enhancer of

Statement

Reference

tara⁰³⁸⁸¹/tara⁰³⁸⁸¹ is a non-enhancer of visible | embryonic stage phenotype of Pc³

(Dutta and Li, 2017)

tara⁰³⁸⁸¹/tara⁰³⁸⁸¹ is a non-enhancer of homeotic | embryonic stage phenotype of Pc³

(Dutta and Li, 2017)

NOT Suppressor of

Statement

Reference

tara⁰³⁸⁸¹/tara⁰³⁸⁸¹ is a non-suppressor of visible | embryonic stage phenotype of Pc³

(Dutta and Li, 2017)

tara⁰³⁸⁸¹/tara⁰³⁸⁸¹ is a non-suppressor of homeotic | embryonic stage phenotype of Pc³

(Dutta and Li, 2017)

Phenotype Manifest In

Enhanced by

Statement

Reference

tara⁰³⁸⁸¹ has wing phenotype, enhanceable by tna¹

(Gutierrez et al., 2003)

tara⁰³⁸⁸¹ has wing phenotype, enhanceable by osa¹

(Gutierrez et al., 2003)

NOT Enhanced by

Statement

Reference

tara⁰³⁸⁸¹ has ventral denticle belt | embryonic stage phenotype, non-enhanceable by Pc³/Pc³

(Dutta and Li, 2017)

NOT suppressed by

Statement

Reference

tara⁰³⁸⁸¹ has ventral denticle belt | embryonic stage phenotype, non-suppressible by Pc³/Pc³

(Dutta and Li, 2017)

Enhancer of

Statement

Reference

tara⁰³⁸⁸¹ is an enhancer of wing phenotype of Ubx^1:Cbx-1

(Dutta and Li, 2017)

tara⁰³⁸⁸¹/tara[+] is an enhancer of wing margin phenotype of Bx¹

(Bejarano et al., 2008)

tara⁰³⁸⁸¹ is an enhancer of wing phenotype of tna¹

(Gutierrez et al., 2003)

tara⁰³⁸⁸¹ is an enhancer of wing phenotype of osa¹

(Gutierrez et al., 2003)

tna^S058302/tara⁰³⁸⁸¹ is an enhancer of wing phenotype of brm²

(Gutierrez et al., 2003)

NOT Enhancer of

Statement

Reference

tara⁰³⁸⁸¹/tara⁰³⁸⁸¹ is a non-enhancer of ventral denticle belt | embryonic stage phenotype of Pc³

(Dutta and Li, 2017)

NOT Suppressor of

Statement

Reference

tara⁰³⁸⁸¹/tara⁰³⁸⁸¹ is a non-suppressor of ventral denticle belt | embryonic stage phenotype of Pc³

(Dutta and Li, 2017)

Additional Comments

Genetic Interactions

Statement

Reference

Less than 1% of brm²/tara⁰³⁸⁸¹ flies have a held-out wings phenotype. 30% of brm²/tna^S058302 tara⁰³⁸⁸¹ flies have a held-out wings phenotype. 31% of osa¹/tara⁰³⁸⁸¹ flies have a held-out wings phenotype. tna^S058302/tara⁰³⁸⁸¹ flies do not have a held-out wings phenotype. 80% of tara⁰³⁸⁸¹/tna¹ flies have a held-out wings phenotype.