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General Information
Symbol
Dmel\BEAF-32UAS.cYa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Yamaguchi
FlyBase ID
FBal0128315
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

UASt regulatory sequences drive expression of the BEAF-32 A isoform.

Allele components
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

BEAF-32Scer\UAS.cYa driven by Scer\GAL4GMR.PF causes a rough eye phenotype. The severity increases if 2 copies of both driver and BEAF-32 construct are inserted.

Flies expressing one copy of BEAF-32Scer\UAS.cYa under the control of Scer\GAL4GMR.PS have rough eyes. The ommatidia lack their regular hexagonal shape and some bristles are missing. The rhabdomeres are irregular in shape. The eye phenotype is more severe if the flies express two copies of BEAF-32Scer\UAS.cYa under the control of Scer\GAL4GMR.PS; many ommatidia appear fused, and missing or additional bristles are apparent. Expression of BEAF-32Scer\UAS.cYa under the control of Scer\GAL4GMR.PS does not result in ectopic incorporation of BrdU in the larval eye imaginal disc. Third larval instar eye discs expressing BEAF-32Scer\UAS.cYa under the control of Scer\GAL4GMR.PS show a significant increase in cell death posterior to the morphogenetic furrow compared to wild type.

Expression of BEAF-32Scer\UAS.cYa under the control of Scer\GAL4en-e16E does not affect wing morphology.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Enhanced by
Statement
Reference

BEAF-32UAS.cYa, Scer\GAL4GMR.PS has visible phenotype, enhanceable by Dll9/Dll[+]

BEAF-32UAS.cYa, Scer\GAL4GMR.PS has visible phenotype, enhanceable by kto[+]/kto1

BEAF-32UAS.cYa, Scer\GAL4GMR.PS has visible phenotype, enhanceable by su(Hw)[+]/su(Hw)2

BEAF-32UAS.cYa, Scer\GAL4GMR.PS has visible phenotype, enhanceable by su(Hw)[+]/su(Hw)8

NOT Enhanced by
Statement
Reference
Suppressed by
NOT suppressed by
Statement
Reference

BEAF-32UAS.cYa, Scer\GAL4GMR.PS has visible phenotype, non-suppressible by Pc1

Suppressor of
Statement
Reference
Other
Phenotype Manifest In
Enhanced by
Statement
Reference

BEAF-32UAS.cYa, Scer\GAL4GMR.PS has eye phenotype, enhanceable by kto[+]/kto1

BEAF-32UAS.cYa, Scer\GAL4GMR.PS has eye phenotype, enhanceable by su(Hw)[+]/su(Hw)2

BEAF-32UAS.cYa, Scer\GAL4GMR.PS has eye phenotype, enhanceable by su(Hw)[+]/su(Hw)8

NOT Enhanced by
Statement
Reference

BEAF-32UAS.cYa, Scer\GAL4GMR.PS has eye phenotype, non-enhanceable by Pc1

BEAF-32UAS.cYa, Scer\GAL4GMR.PS has eye phenotype, non-enhanceable by ScmD1

BEAF-32UAS.cYa, Scer\GAL4GMR.PS has eye phenotype, non-enhanceable by brm2

BEAF-32UAS.cYa, Scer\GAL4GMR.PS has eye phenotype, non-enhanceable by esc1

BEAF-32UAS.cYa, Scer\GAL4GMR.PS has eye phenotype, non-enhanceable by kis1

BEAF-32UAS.cYa, Scer\GAL4GMR.PS has eye phenotype, non-enhanceable by mor1

BEAF-32UAS.cYa, Scer\GAL4GMR.PS has eye phenotype, non-enhanceable by osa2

BEAF-32UAS.cYa, Scer\GAL4GMR.PS has eye phenotype, non-enhanceable by phob

BEAF-32UAS.cYa, Scer\GAL4GMR.PS has eye phenotype, non-enhanceable by sxc1

BEAF-32UAS.cYa, Scer\GAL4GMR.PS has eye phenotype, non-enhanceable by trx1

Suppressed by
NOT suppressed by
Statement
Reference

BEAF-32UAS.cYa, Scer\GAL4GMR.PS has eye phenotype, non-suppressible by esc1

BEAF-32UAS.cYa, Scer\GAL4GMR.PS has eye phenotype, non-suppressible by kis1

BEAF-32UAS.cYa, Scer\GAL4GMR.PS has eye phenotype, non-suppressible by mor1

BEAF-32UAS.cYa, Scer\GAL4GMR.PS has eye phenotype, non-suppressible by osa2

BEAF-32UAS.cYa, Scer\GAL4GMR.PS has eye phenotype, non-suppressible by phob

BEAF-32UAS.cYa, Scer\GAL4GMR.PS has eye phenotype, non-suppressible by sxc1

BEAF-32UAS.cYa, Scer\GAL4GMR.PS has eye phenotype, non-suppressible by trx1

BEAF-32UAS.cYa, Scer\GAL4GMR.PS has eye phenotype, non-suppressible by Pc1

BEAF-32UAS.cYa, Scer\GAL4GMR.PS has eye phenotype, non-suppressible by ScmD1

BEAF-32UAS.cYa, Scer\GAL4GMR.PS has eye phenotype, non-suppressible by brm2

Suppressor of
Other
Statement
Reference
Additional Comments
Genetic Interactions
Statement
Reference

Coexpression of BacA\p35GMR.PH strongly suppresses the rough eye phenotype caused by expression of BEAF-32Scer\UAS.cYa under the control of Scer\GAL4GMR.PS. The rough eye phenotype caused by expression of BEAF-32Scer\UAS.cYa under the control of Scer\GAL4GMR.PS is strongly enhanced by su(Hw)2/+ or su(Hw)8/+. The rough eye phenotype caused by expression of BEAF-32Scer\UAS.cYa under the control of Scer\GAL4GMR.PS is enhanced by kto1/+. The rough eye phenotype caused by expression of BEAF-32Scer\UAS.cYa under the control of Scer\GAL4GMR.PS is weakly enhanced by Dll9. Flies expressing BEAF-32Scer\UAS.cYa under the control of Scer\GAL4GMR.PS in a Dll5 background have a severe small eye phenotype.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
BEAF-32Scer\UAS.cYa
BEAF-32UAS.cYa
Name Synonyms
Saccharomyces cerevisiae UAS construct a of Yamaguchi
Secondary FlyBase IDs
    References (3)