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General Information
Symbol
Dmel\Dll5
Species
D. melanogaster
Name
FlyBase ID
FBal0001002
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology

Polytene chromosomes normal.

Nature of the lesion
Statement
Reference
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Embryos have normal mouth hooks and ventral organs, but missing an average of 5 cirri from the anterior row and 7 cirri from the posterior row. Also the ventral organ often includes extra papillae of unknown origin. Dll mutations do not revert the homeotic transformations induced by ectopic Dfd expression.

Heterozygotes show a transformation of distal segments of the antenna to the corresponding segments of the mesothoracic leg. Homozygous and hemizygous embryos lack the H piece, labial sense organ, antennal sense organ, maxillary sense organ and Keilin's organs.

Dll5/+ like Dll1/+. Dll5/Dll5 and Dll5/Dll1 are late embryonic lethals; show loss of antennae, maxillary and labial sense organs, as well as the 'H' piece and Keilin's organs from all three thoracic segments. Occasional abnormalities in setal bands of segments posterior to prothorax; setal bands or spinules may be deleted or adjacent bands fused. Posterior end of larva normal.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Enhancer of
Statement
Reference
Other
Phenotype Manifest In
Enhancer of
Statement
Reference

Dll5/Dll[+] is an enhancer of eye phenotype of DrefUAS.cSa, Scer\GAL4GMR.PS

NOT Enhancer of
Statement
Reference

Dll5/Dll[+] is a non-enhancer of wing vein | ectopic phenotype of Snr1E1

Suppressor of
Statement
Reference

Dll5/Dll[+] is a suppressor of wing margin phenotype of Scer\GAL4NP7148, ssUAS.A5

NOT Suppressor of
Statement
Reference

Dll5/Dll[+] is a non-suppressor of wing vein | ectopic phenotype of Snr1E1

Other
Statement
Reference
Additional Comments
Genetic Interactions
Statement
Reference

Genetic crossing of the DrefScer\UAS.cSa expressing strain with Dll5 results in a severe small eye phenotype.

Flies expressing BEAF-32Scer\UAS.cYa under the control of Scer\GAL4GMR.PS in a Dll5 background have a severe small eye phenotype.

Has little or no effect on the phenotype of E2fGMR.PD DpGMR.PD BacA\p35GMR.PH flies.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (2)
Notes on Origin
Discoverer

Tiong, 1983.

External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
References (19)