Heterozygotes show a significant increase in double strand break (DSB) repair via homologous recombination and a corresponding decrease in DSB repair by nonhomologous end-joining compared to controls in a somatic DSB repair assay, when whd80k17 is used as the recipient allele bearing the target break site.
Heterozygous males do not have ectopic sex combs on the second and third legs.
esc1 males have ectopic sex combs on the second and third leg.
Sex combs may be present on all six legs of male; at least one extra sex comb present in majority of males. Expression affected by culture conditions. When expressivity high, extra transverse bristle rows appear between sixth and eighth longitudinal rows of bristles, mainly on distal portion of basitarsus and tibia of third legs in both sexes and ectopic ones on the second legs; accompanied by shortening of affected leg segments. RK2.
Sex comb development autonomous in mosaics produced by somatic crossing over.
Interactions with Pc and Scr alleles are described.