FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Aberration: Dmel\Df(2L)VA12
Open Close
General Information
Symbol
Df(2L)VA12
Species
D. melanogaster
Name
FlyBase ID
FBab0001665
Feature type
chromosomal_deletion
Also Known As
VA12
Computed Breakpoints include

37C2-37C5;38B5-38C1

Features within 37C2--38C1
Sequence coordinates
Member of large scale dataset(s)
Nature of Aberration
Cytological Order
Progenitor
Mutagen
gamma ray
(Stathakis et al., 1995, Wright et al., 1981)
Class of aberration (relative to wild type)
chromosomal_deletion
(FlyBase, 2007)
Class of aberration (relative to progenitor)
chromosomal_deletion
(Fitzpatrick et al., 1995, Pauli et al., 1995, Stathakis et al., 1995, Dura et al., 1993, Whalen and Wilson, 1986, Gilbert et al., 1984, Wright et al., 1981)
Breakpoints

37C1-37D1;38B1-38C2

(Wright et al., 1981)

37C1-37C5;38B1-38C2

(Whalen and Wilson, 1986, Gilbert et al., 1984)

37C2-37C5;38B2-38C1

(Fitzpatrick et al., 1995, Pauli et al., 1995, Stathakis et al., 1995, Dura et al., 1993)
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data

l(2)37Cg << bk1 << brat << l(2)38Aa << bk2 << ms(2)38C

Genetic mapping information
Comments

Breakpoint(s) molecularly mapped

(Gilbert et al., 1984, Hirsh and Davidson, 1981)

Ddc DNA coordinates from Gilbert, Hirsh and Wright, 1984, Genetics 106: 679-84: Distal breakpoint between +25.5 and +28.1 kb

Comments on Cytology

Left limit of break 1 from polytene analysis (FBrf0080317) Right limit of break 1 from polytene analysis (FBrf0040975) Left limit of break 2 from inclusion of l(2)38Aa (citation unavailable) Right limit of break 2 from polytene analysis (FBrf0080317)

Sequence Crossreferences
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Genes NOT Deleted / Disrupted
Complementation Data
 
Acn
(Wright, 1996, Stathakis et al., 1995, Pentz et al., 1986, Gilbert et al., 1984, Wright et al., 1981)
AcpC
(Whalen and Wilson, 1986)
amd
(Wright, 1996, Stathakis et al., 1995, Gilbert et al., 1984, Wright et al., 1981)
AsnRS
(Wright, 1996, Stathakis et al., 1995, Pentz et al., 1986, Wright et al., 1981)
Bl
(Butler et al., 2001)
cad
(Butler et al., 2001)
Catsup
(Wright, 1996, Stathakis et al., 1995, Pentz et al., 1986, Gilbert et al., 1984, Wright et al., 1981)
cub
(Wright, 1996, Stathakis et al., 1995, Pentz et al., 1986, Gilbert et al., 1984)
DCTN6-p27
(Wright, 1996, Stathakis et al., 1995, Pentz et al., 1986, Wright et al., 1981)
Ddc
(Wright, 1996, Stathakis et al., 1995, Gilbert et al., 1984, Wright et al., 1981)
hook
(Wright, 1996, Stathakis et al., 1995, Pentz et al., 1986, Gilbert et al., 1984, Wright et al., 1981)
l(2)37Bb
(Wright, 1996, Stathakis et al., 1995, Pentz et al., 1986, Gilbert et al., 1984, Wright et al., 1981)
l(2)37Cb
(Wright, 1996, Stathakis et al., 1995, Pentz et al., 1986, Wright et al., 1981)
l(2)37Cd
(Wright, 1996, Stathakis et al., 1995, Pentz et al., 1986, Wright et al., 1981)
l(2)38Db
(Butler et al., 2001)
l(2)k09314b
(BDGP Project Members, 1994-1999)
Lim3
(Wright, 1996, Stathakis et al., 1995, Pentz et al., 1986, Gilbert et al., 1984, Wright et al., 1981)
mib2
(Wright, 1996, Stathakis et al., 1995, Pentz et al., 1986, Gilbert et al., 1984)
Phb1
(Wright, 1996, Stathakis et al., 1995, Pentz et al., 1986, Wright et al., 1981)
Polr1D
(Wright, 1996, Stathakis et al., 1995, Pentz et al., 1986)
Rpn3
(Wright, 1996, Stathakis et al., 1995, Pentz et al., 1986, Gilbert et al., 1984)
spir
(Butler et al., 2001)
Molecular Data
 
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
 
Molecular Data
 
Affected Genes Inferred by Location (0)
    If no genes are listed here, it may be because the affected region is very large. The JBrowse insert above may show an error for the same reason, and other FlyBase tools such as CytoSearch may also fail for large regions. You can contact FlyBase for more help.
    In these cases, there will be no "Export to Hitlist" button to the left.
    Phenotypic Data
    In combination with other aberrations
    NOT in combination with other aberrations

    Mutation does not affect the level of w expression in ph-plac+3 flies.

    (Fauvarque et al., 1995)

    Heterozygosity for this deletion has no effect on the mutant ovarian phenotype of ovoD2.

    (Pauli et al., 1995)
    Stocks (2)
    Notes on Origin
    Discoverer

    A. Tomsett.

     
    Balancer / Genotype Variants of the Aberration
     
    Separable Components
     
    Other Comments
     

    The Df(2L)VA12 chromosome acts as a dominant moderate suppressor of telomeric silencing (assayed using the effect of the chromosome on the eye colour phenotype of flies carrying "P{wvar}KR3-2", a stable "brown-red" variant of the P{3'WP-2,wvar}2Lt insertion), but this is a false positive result (the suppressor is not within the bounds of the deficient region) because the region of the deficiency is covered by one or more nonsuppressing deficiencies.

    (Mason et al., 2004)

    37C2-37C5 breakpoint is between position +26.5 and +29.1 on the Ddc map relative to the HpaI restriction site near the 3' end of Ddc.

    (Stathakis et al., 1995)
    Synonyms and Secondary IDs (3)
    Reported As
    Symbol Synonym
    Df(2L)VA12
    (Casso et al., 2008)
    Df(2L)VA12
    (Tully et al., 1992)
    VA12
    (Hirose et al., 2001, Yamaguchi et al., 2001, Yamaguchi et al., 1999)
    Name Synonyms
    Secondary FlyBase IDs
      References (30)