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General Information
Symbol
Df(2L)VA12
Species
D. melanogaster
Name
FlyBase ID
FBab0001665
Feature type
Also Known As
VA12
Computed Breakpoints include

37C2-37C5;38B5-38C1

Sequence coordinates
Member of large scale dataset(s)
Nature of Aberration
Cytological Order
Progenitor
Class of aberration (relative to wild type)
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data

l(2)37Cg << bk1 << brat << l(2)38Aa << bk2 << ms(2)38C

Genetic mapping information
Comments

Breakpoint(s) molecularly mapped

Ddc DNA coordinates from Gilbert, Hirsh and Wright, 1984, Genetics 106: 679-84: Distal breakpoint between +25.5 and +28.1 kb

Comments on Cytology

Left limit of break 1 from polytene analysis (FBrf0080317) Right limit of break 1 from polytene analysis (FBrf0040975) Left limit of break 2 from inclusion of l(2)38Aa (citation unavailable) Right limit of break 2 from polytene analysis (FBrf0080317)

Sequence Crossreferences
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Genes NOT Deleted / Disrupted
Complementation Data
 
Molecular Data
 
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
 
Molecular Data
 
Affected Genes Inferred by Location
    Phenotypic Data
    In combination with other aberrations
    NOT in combination with other aberrations

    Mutation does not affect the level of w expression in ph-plac+3 flies.

    Heterozygosity for this deletion has no effect on the mutant ovarian phenotype of ovoD2.

    Stocks (2)
    Notes on Origin
    Discoverer

    A. Tomsett.

     
    Balancer / Genotype Variants of the Aberration
     
    Separable Components
     
    Other Comments
     

    The Df(2L)VA12 chromosome acts as a dominant moderate suppressor of telomeric silencing (assayed using the effect of the chromosome on the eye colour phenotype of flies carrying "P{wvar}KR3-2", a stable "brown-red" variant of the P{3'WP-2,wvar}2Lt insertion), but this is a false positive result (the suppressor is not within the bounds of the deficient region) because the region of the deficiency is covered by one or more nonsuppressing deficiencies.

    37C2-37C5 breakpoint is between position +26.5 and +29.1 on the Ddc map relative to the HpaI restriction site near the 3' end of Ddc.

    Synonyms and Secondary IDs (3)
    Reported As
    Name Synonyms
    Secondary FlyBase IDs
      References (30)