FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\numbNP2301
Open Close
General Information
Symbol
Dmel\numbNP2301
Species
D. melanogaster
Name
FlyBase ID
FBal0228259
Feature type
allele
Associated gene
Dmel\numb
Associated Insertion(s)
P{GawB}numbNP2301
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Associated Insertion(s)
    P{GawB}numbNP2301
    Cytology
    Description
    Allele components
    Component
    Use(s)
    Inserted element
    P{GawB}
    Encoded product / tool
    GAL4
    Mutations Mapped to the Genome
    Curation Data
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        numb15/numbNP2301 transheterozygosity leads to supernumerary type II neuroblasts in the larval optic lobe.

        (Komori et al., 2018)

        Supernumerary neuroblasts are seen in numbNP2301 mutant larval brains.

        (Janssens et al., 2014)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Enhanced by
        Statement
        Reference

        numbNP2301/numb15 has increased cell number | larval stage phenotype, enhanceable by insb[+]/insbexA45

        (Komori et al., 2018)

        numbNP2301/numb15 has increased cell number | larval stage phenotype, enhanceable by bratDG19310/brat11

        (Komori et al., 2018)

        numbNP2301 has abnormal neuroanatomy phenotype, enhanceable by brm[+]/brm2

        (Janssens et al., 2014)

        numbNP2301 has abnormal neuroanatomy phenotype, enhanceable by mor[+]/mor1

        (Janssens et al., 2014)

        numbNP2301 has abnormal neuroanatomy phenotype, enhanceable by erm[+]/erm1

        (Janssens et al., 2014)
        Enhancer of
        Statement
        Reference

        numbNP2301/numb15 is an enhancer of increased cell number | larval stage phenotype of bratDG19310/brat11

        (Komori et al., 2018)
        Phenotype Manifest In
        Additional Comments
        Genetic Interactions
        Statement
        Reference

        One copy of brm2 enhances the supernumerary neuroblast phenotype seen in numbNP2301 mutant larval brains.

        One copy of mor1 enhances the supernumerary neuroblast phenotype seen in numbNP2301 mutant larval brains.

        One copy of erm1 enhances the supernumerary neuroblast phenotype seen in numbNP2301 mutant larval brains.

        (Janssens et al., 2014)
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (2)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (1)
        Reported As
        Symbol Synonym
        numbNP2301
        (Komori et al., 2018)
        Name Synonyms
        Secondary FlyBase IDs
          References (3)