FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\ph-d503
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General Information
Symbol
Dmel\ph-d503
Species
D. melanogaster
Name
FlyBase ID
FBal0013757
Feature type
allele
Associated gene
Dmel\ph-d
Associated Insertion(s)
Carried in Construct
Also Known As
ph503
Key Links
Allele class

amorphic allele - genetic evidence

Mutagen
Nature of the Allele
Allele class

amorphic allele - genetic evidence

(Gindhart and Kaufman, 1995, Cheng et al., 1994, Dura et al., 1987)
Mutagen
ethyl methanesulfonate
(Dura et al., 1987)
Progenitor genotype
ph-d209
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Over 50% of mutant embryos in anaphase, show multiple chromosomal bridges and in some cases have chromosomal breaks.

      (Lupo et al., 2001)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressor of
      Statement
      Reference

      ph-d[+]/ph-d503 is a suppressor of visible | dominant | homeotic phenotype of brm[+]/brm2, trxE2

      (Gildea et al., 2000)

      ph-d[+]/ph-d503 is a suppressor of visible | dominant | homeotic phenotype of ash117, trxB11/trx[+]

      (Gildea et al., 2000)

      ph-d503 is a suppressor of abnormal eye color phenotype of wT81

      (Netter et al., 1998)
      Phenotype Manifest In
      NOT Enhancer of
      Statement
      Reference

      ph-d503 is a non-enhancer of eye phenotype of CycEJP

      (Brumby et al., 2002)
      Suppressor of
      Statement
      Reference

      ph-d[+]/ph-d503 is a suppressor of adult metathoracic segment phenotype of brm[+]/brm2, trxE2

      (Gildea et al., 2000)

      ph-d[+]/ph-d503 is a suppressor of adult metathoracic segment phenotype of ash117, trxB11/trx[+]

      (Gildea et al., 2000)
      NOT Suppressor of
      Statement
      Reference

      ph-d503 is a non-suppressor of eye phenotype of CycEJP

      (Brumby et al., 2002)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Strong suppressor of eye pigment phenotype of wT81.

      (Netter et al., 1998)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (2)
      Notes on Origin
      Discoverer
      Comments
      Comments

      Weak derepression of en expression.

      (Moazed and O'Farrell, 1992)

      Shows no significant dominant suppression of the nos mutant phenotype.

      (Pelegri and Lehmann, 1994)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      References (17)