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General Information
Symbol
Dmel\vnC221
Species
D. melanogaster
Name
FlyBase ID
FBal0081947
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

vn1/vnC221 animals lack the L4 wing vein.

Heterozygotes show an incomplete or deleted anterior crossvein in 5% of wings.

vnC221/vn1 transheterozygotes are viable and display deletions of the anterior crossvein and a portion of wing vein L4 proximal to the posterior crossvein. vnC221/vnddd-13 transheterozygotes are semi-viable at 25oC, escapers survive for 3 days and are of normal appearance except for held-out wings and the absence of anterior cross vein.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Suppressed by
Statement
Reference

vnC221/vn1 has visible phenotype, suppressible by Bap170hfl1/Bap170[+]

Enhancer of
Statement
Reference

vn[+]/vnC221 is an enhancer of abnormal size | adult stage phenotype of sl2

vnC221 is an enhancer of visible phenotype of Egfrt1

Suppressor of
Statement
Reference

vn[+]/vnC221 is a suppressor of visible phenotype of Scer\GAL4Tub.PU, cswN308D.UASp

vnC221 is a suppressor of visible phenotype of Su(H)16

vnC221 is a suppressor of visible phenotype of N55e11

Other
Phenotype Manifest In
Enhanced by
Statement
Reference

vnC221 has humeral bristle phenotype, enhanceable by brm[+]/brm2

Suppressed by
Statement
Reference

vnC221/vn1 has wing vein L4 phenotype, suppressible by Bap170hfl1/Bap170[+]

Enhancer of
Statement
Reference

vn[+]/vnC221 is an enhancer of wing blade phenotype of sl2

vnC221 is an enhancer of wing vein L4 phenotype of Egfrt1

Suppressor of
Statement
Reference

vn[+]/vnC221 is a suppressor | partially of wing vein | ectopic phenotype of sl2

vn[+]/vnC221 is a suppressor of wing vein | ectopic phenotype of Scer\GAL4Tub.PU, cswN308D.UASp

vnC221 is a suppressor of wing phenotype of Su(H)16

vnC221 is a suppressor of wing phenotype of N55e11

Other
Additional Comments
Genetic Interactions
Statement
Reference

One copy of vnC221 enhances the reduction in wing blade area seen in homozygous sl2 males.

One copy of vnC221 partially suppresses the ectopic wing vein phenotype seen in sl2 homozygotes.

One copy of vnC221 partially suppresses the percentage of sl2 mutant ommatidia that contain extra R7 photoreceptors.

The loss of wing vein L4 which is seen in vn1/vnC221 animals is rescued by Bap170hfl1/+ in 90% of cases.

The presence of a vnC221 background causes minor suppression of ectopic wing vein formation found in cswY279C.Scer\UAS (Scer\GAL4tub) mutants.

vnC221/Snr1E1 animals show an incomplete or deleted anterior crossvein in 15% of wings.

Mutation enhances the Egfr mutant wing phenotype, the interaction is not specific to Egfrt1.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (2)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
References (13)