FlyBase Allele Report: Dmel\gro[C105]

General Information

Symbol

Dmel\gro^C105

Species

D. melanogaster

Name

FlyBase ID

FBal0082904

Feature type

allele

Associated gene

Dmel\gro

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

Mutagen

ethyl methanesulfonate

Nature of the Allele

Allele class

Mutagen

ethyl methanesulfonate

(Price et al., 1997)

Progenitor genotype

Cytology

Description

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

partially lethal - majority live

(Price et al., 1997)

visible

(Price et al., 1997)

visible (with gro¹)

(Haussmann et al., 2008)

Phenotype Manifest In

adult head & microchaeta

(Price et al., 1997)

frontal bristle | increased number (with gro¹)

(Haussmann et al., 2008)

ocellus

(Price et al., 1997)

wing vein L5

(Price et al., 1997)

Detailed Description

Statement

Reference

gro¹/gro^C105 adults have an overproliferation of frontal bristles on the head.

(Haussmann et al., 2008)

gro^C105/gro¹ mutants display enlarged and fused ocelli, and an increased number of fronto-orbital microchaetae. gro^C105/gro^E28 mutants are semi-viable, escapers have rough eyes and thickened wing vein L5.

(Price et al., 1997)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhanced by

Statement

Reference

gro^C105/gro¹ has visible phenotype, enhanceable by CG12299^EY01579

(Haussmann et al., 2008)

Enhancer of

Statement

Reference

gro^C105 is an enhancer of visible phenotype of Egfr^t1

(Price et al., 1997)

Suppressor of

Statement

Reference

gro^C105 is a suppressor of visible phenotype of Su(H)¹⁶

(Price et al., 1997)

Other

Statement

Reference

CG8924^EY00245, gro^C105/gro¹ has visible phenotype

(Haussmann et al., 2008)

Clamp^KG00473, gro^C105/gro¹ has visible phenotype

(Haussmann et al., 2008)

Ac3^EY10141, gro^C105/gro¹ has visible phenotype

(Haussmann et al., 2008)

H^C21, gro^C105 has visible phenotype

(Price et al., 1997)

gro^C105, vn^C221 has visible phenotype

(Price et al., 1997)

E(Egfr)C22^C22, gro^C105 has visible phenotype

(Price et al., 1997)

Phenotype Manifest In

Enhanced by

Statement

Reference

gro^C105/gro¹ has frontal bristle phenotype, enhanceable by CG12299^EY01579

(Haussmann et al., 2008)

Enhancer of

Statement

Reference

gro^C105/gro[+] is an enhancer of wing vein | ectopic phenotype of Snr1^E1

(Marenda et al., 2004)

gro^C105 is an enhancer of wing vein L4 phenotype of Egfr^t1

(Price et al., 1997)

gro^C105 is an enhancer of anterior crossvein phenotype of Egfr^t1

(Price et al., 1997)

NOT Enhancer of

Statement

Reference

gro^C105, Scer\GAL4^30A is a non-enhancer of wing phenotype of Pka-C1^UAS.cKa, Scer\GAL4^30A

(Kiger et al., 2001)

Suppressor of

Statement

Reference

gro^C105 is a suppressor of wing phenotype of Su(H)¹⁶

(Price et al., 1997)

NOT Suppressor of

Statement

Reference

gro^C105, Scer\GAL4^30A is a non-suppressor of wing phenotype of Pka-C1^UAS.cKa, Scer\GAL4^30A

(Kiger et al., 2001)

Other

Statement

Reference

CG8924^EY00245, gro^C105/gro¹ has frontal bristle phenotype

(Haussmann et al., 2008)

Clamp^KG00473, gro^C105/gro¹ has frontal bristle phenotype

(Haussmann et al., 2008)

Ac3^EY10141, gro^C105/gro¹ has frontal bristle phenotype

(Haussmann et al., 2008)

H^C21, gro^C105 has adult head & microchaeta phenotype

(Price et al., 1997)

gro^C105, vn^C221 has anterior crossvein phenotype

(Price et al., 1997)

gro^C105, vn^C221 has wing vein L4 phenotype

(Price et al., 1997)

E(Egfr)C22^C22, gro^C105 has anterior crossvein phenotype

(Price et al., 1997)

Additional Comments

Genetic Interactions

Statement

Reference

The overproliferation of frontal bristles on the head that is seen in gro¹/gro^C105 adults is enhanced if they are also hemizygous for CG12299^EY01579.

gro¹/gro^C105 ; CG8924^EY00245 double mutants have missing frontal bristles in 57% of cases.

gro¹/gro^C105 ; CG1832^KG00473/CG1832^KG00473 adults have extra frontal bristles on the head in 65% of cases and have missing frontal bristles in 14% of cases.

gro¹/gro^C105 ; Ac3^EY10141 double mutants have extra frontal bristles on the head in 55% of cases and have missing frontal bristles in 33% of cases.

gro¹/gro^C105 ; BCL7-like^EY10009/BCL7-like^EY00880 double mutants have extra frontal bristles on the head in 3% of cases and have missing frontal bristles in 96% of cases.

(Haussmann et al., 2008)

Mutation enhances the Egfr mutant wing phenotype, the interaction is not specific to Egfr^t1.

(Price et al., 1997)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (2)

2124

106671

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (4)

Reported As

Symbol Synonym

E(Egfr)C105

(Price et al., 1997)

Gro^C105

(Zhu et al., 2017)

gro^C105

(Nair et al., 2020)

gro^c105

(Haussmann et al., 2008)

Name Synonyms

Secondary FlyBase IDs

References (8)

Report Sections

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