Homozygotes die during the late embryonic and first larval instar stages.
Dominant suppressor of z1 wis mutant phenotype. Fails to suppress the mutant phenotype of z1 w+UZ, z1 Dp(1;1)w+61e19, z1 wsp2, z1 wsp55, z1 wnegro, z1 wzm, z1 wch and z1 wa, wa, wa2, wbf2, wbfR61d5, wbf, wh and wco individuals.
Heterozygotes have reduced viability. Females fertile at 16oC but sterile at 25oC.
Body size and bristles reduced in heterozygotes; irregular facets in upper half of eye. Heterozygous females virtually sterile at temperatures above 18oC; surviving offspring frequently have missing legs or halteres, somewhat narrowed wings, and reduced bristles. Homozygotes lethal. Selected on the basis of a dominant suppressor of zeste phenotype. Characterized by relatively frequent reversions of all features of the phenotype save homozygous lethality. One such revertant found to be deficient for the tip of 2L, suggesting a gain of function rather than haplo insufficiency as the nature of the mutation (Kennison).