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General Information
Symbol
Dmel\sxc4
Species
D. melanogaster
Name
FlyBase ID
FBal0016678
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Nature of the Allele
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Nucleotide change:

A5327950T

Reported nucleotide change:

A?T

Amino acid change:

N948I | sxc-PA; N948I | sxc-PB; N948I | sxc-PC

Reported amino acid change:

N948I

Comment:

Site of nucleotide substitution in mutant inferred by FlyBase based on reported amino acid change.

Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

Amino acid replacement: N948I.

Nucleotide substitution of AAT to ATT results in amino acid replacement of N to I at position 948.

Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Flies transheterozygous for sxc4 and sxc6 or sxc7 develop into pharate adults showing a typical sxc mutant phenotype.

sxc2/sxc4 flies are viable and fertile, but exhibit wing abnormalities suggestive of wing-to-haltere transformations.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Suppressor of
Statement
Reference

sxc[+]/sxc4 is a suppressor of visible | dominant | homeotic phenotype of brm[+]/brm2, trxE2

sxc[+]/sxc4 is a suppressor of visible | dominant | homeotic phenotype of ash117, trxB11/trx[+]

Phenotype Manifest In
Suppressor of
Statement
Reference

sxc[+]/sxc4 is a suppressor | partially of adult mesothoracic segment | ectopic phenotype of E(z)Trm

sxc[+]/sxc4 is a suppressor | partially of adult metathoracic segment phenotype of E(z)Trm

sxc[+]/sxc4 is a suppressor | partially of adult prothoracic segment phenotype of E(z)Trm

sxc[+]/sxc4 is a suppressor of adult metathoracic segment phenotype of brm[+]/brm2, trxE2

sxc[+]/sxc4 is a suppressor of adult metathoracic segment phenotype of ash117, trxB11/trx[+]

Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Name Synonyms
Secondary FlyBase IDs
    References (9)