FlyBase Allele Report: Dmel\nmo[unspecified]

General Information

Symbol

Dmel\nmo^unspecified

Species

D. melanogaster

Name

FlyBase ID

FBal0104469

Feature type

allele

Associated gene

Dmel\nmo

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

Mutagen

Nature of the Allele

Allele class

Mutagen

Progenitor genotype

Cytology

Description

FlyBase curator comment: this entry is used to capture phenotypic information when the particular allele (or allele combination) used by the author could not be determined but the context of the experiment suggests that the phenotype being described is some kind of loss of function.

(FlyBase Curators, 2025-)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal neuroanatomy | third instar larval stage

(Merino et al., 2009)

Phenotype Manifest In

NMJ bouton | third instar larval stage

(Merino et al., 2009)

Detailed Description

Statement

Reference

The number of boutons per muscle surface area is reduced at the neuromuscular junction in mutant third instar larvae.

(Merino et al., 2009)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressed by

Statement

Reference

nmo^unspecified has abnormal neuroanatomy | third instar larval stage phenotype, suppressible by Scer\GAL4^BG380/tkv^{Q199D.UAS.Tag:HA}

(Merino et al., 2009)

nmo^unspecified has visible phenotype, suppressible by pan^ΔN.UAS/Scer\GAL4^bs-1348

(Verheyen et al., 2001)

nmo^unspecified has visible phenotype, suppressible by Scer\GAL4^32B/Delta^UAS.cDa

(Verheyen et al., 2001)

NOT suppressed by

Statement

Reference

nmo^unspecified has abnormal neuroanatomy | third instar larval stage phenotype, non-suppressible by Scer\GAL4^BG380/Mad^UAS.Tag:MYC

(Merino et al., 2009)

Enhancer of

Statement

Reference

nmo^unspecified/nmo[+] is an enhancer of abnormal planar polarity phenotype of Scer\GAL4^hs.2sev, sca^UAS.cEa

(Chou and Chien, 2002)

Suppressor of

Statement

Reference

nmo^unspecified/nmo[+] is a suppressor of visible phenotype of hid^GMR.PG

(Mirkovic et al., 2002)

nmo^unspecified is a suppressor of lethal phenotype of Scer\GAL4^bs-1348, pan^ΔN.UAS

(Verheyen et al., 2001)

Phenotype Manifest In

Suppressed by

Statement

Reference

nmo^unspecified has NMJ bouton | third instar larval stage phenotype, suppressible by Scer\GAL4^BG380/tkv^{Q199D.UAS.Tag:HA}

(Merino et al., 2009)

nmo^unspecified has wing vein | ectopic phenotype, suppressible by Scer\GAL4^32B/Delta^UAS.cDa

(Verheyen et al., 2001)

nmo^unspecified has wing vein | ectopic phenotype, suppressible by pan^ΔN.UAS/Scer\GAL4^bs-1348

(Verheyen et al., 2001)

NOT suppressed by

Statement

Reference

nmo^unspecified has NMJ bouton | third instar larval stage phenotype, non-suppressible by Scer\GAL4^BG380/Mad^UAS.Tag:MYC

(Merino et al., 2009)

Enhancer of

Statement

Reference

nmo^unspecified/nmo[+] is an enhancer of ommatidium phenotype of Scer\GAL4^hs.2sev, sca^UAS.cEa

(Chou and Chien, 2002)

NOT Enhancer of

Statement

Reference

nmo^unspecified is a non-enhancer of phenotype of Hsap\RALA^G23V.GMR

(Sawamoto et al., 1999)

Suppressor of

Statement

Reference

nmo^unspecified/nmo[+] is a suppressor of eye phenotype of hid^GMR.PG

(Mirkovic et al., 2002)

NOT Suppressor of

Statement

Reference

nmo^unspecified is a non-suppressor of phenotype of Hsap\RALA^G23V.GMR

(Sawamoto et al., 1999)

Additional Comments

Genetic Interactions

Statement

Reference

Expression of Mad^{Scer\UAS.T:Hsap\MYC} under the control of Scer\GAL4^BG380 does not suppress the reduction in the number of boutons per muscle surface area which is seen at the neuromuscular junction in nmo^unspecified third instar larvae.

Expression of tkv^{Q199D.Scer\UAS.T:Ivir\HA1} under the control of Scer\GAL4^BG380 significantly suppresses the reduction in the number of boutons per muscle surface area which is seen at the neuromuscular junction in nmo^unspecified third instar larvae.

(Merino et al., 2009)

The under-rotation defect exhibited by the ommatidia in the eye discs of sca^Scer\UAS.cEa; Scer\GAL4^hs.2sev larvae, is enhanced by nmo^unspecified/+.

(Chou and Chien, 2002)

Heterozygosity for nmo^unspecified partially rescues the small eye size of W^GMR.PG animals.

(Mirkovic et al., 2002)

Expression of Dl^Scer\UAS.cDa under the control of Scer\GAL4^32B suppresses the extra wing vein phenotype of nmo^unspecified flies. Expression of pan^ΔN.Scer\UAS under the control of Scer\GAL4^bs-1348 suppresses the extra wing vein phenotype of nmo^unspecified flies.

(Verheyen et al., 2001)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

nmo^unspecified

Name Synonyms

Secondary FlyBase IDs

References (6)

Report Sections

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