FlyBase Allele Report: Dmel\lqf[AG]

General Information

Symbol

Dmel\lqf^AG

Species

D. melanogaster

Name

FlyBase ID

FBal0104486

Feature type

allele

Associated gene

Dmel\lqf

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

Mutagen

X ray

Nature of the Allele

Allele class

Mutagen

X ray

(Cadavid et al., 2000)

Progenitor genotype

Caused by aberration

In(3L)lqf^AG

Cytology

Description

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal | recessive

(Cadavid et al., 2000)

Phenotype Manifest In

dorsal vessel wall cell | increased number

(Tian et al., 2004)

embryonic somatic muscle cell | dorsal

(Tian et al., 2004)

muscle cell of A1-7 dorsal acute muscle 1

(Tian et al., 2004)

Detailed Description

Statement

Reference

Homozygous embryos have an excess of cardioblasts. The somatic muscle pattern appears grossly normal in mutant embryos, but the size of the dorsal muscles (such as the DA1 muscle) appears reduced. The mutant DA1 muscle contains fewer nuclei than the wild-type DA1 muscle.

(Tian et al., 2004)

lqf^AG/Df(3L)lqf-cE278 animals die as embryos.

(Cadavid et al., 2000)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhancer of

Statement

Reference

lqf^AG/lqf[+] is an enhancer of visible phenotype of faf^FO8/faf^BX3

(Cadavid et al., 2000)

Suppressor of

Statement

Reference

lqf^AG/lqf[+] is a suppressor of abnormal planar polarity phenotype of Rala^EE1

(Cho and Fischer, 2011)

lqf^AG/lqf[+] is a suppressor of visible phenotype of Rala^EE1

(Cho and Fischer, 2011)

Phenotype Manifest In

Enhancer of

Statement

Reference

lqf^AG/lqf[+] is an enhancer of eye phenotype of faf^FO8/faf^BX3

(Cadavid et al., 2000)

lqf^AG is an enhancer of phenotype of faf^unspecified

(Cadavid et al., 2000)

Suppressor of

Statement

Reference

lqf^AG/lqf[+] is a suppressor of ommatidium phenotype of Rala^EE1

(Cho and Fischer, 2011)

lqf^AG/lqf[+] is a suppressor of eye photoreceptor cell phenotype of Rala^EE1

(Cho and Fischer, 2011)

Additional Comments

Genetic Interactions

Statement

Reference

lqf^AG dominantly suppresses the rough eye phenotype of Rala^EE1/Y adults, with a greater proportion of ommatidia being completely normal in the double mutant flies.

(Cho and Fischer, 2011)

faf^BX3/faf^FO8 eyes are nearly wild type. The eyes are severely malformed if the flies are also carrying one copy of lqf^AG.

(Cadavid et al., 2000)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescued by

lqf^AG/Df(3L)lqf-cE278 is rescued by lqf^+t19G

(Cadavid et al., 2000)

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

Selected as: an enhancer of the faf mutant phenotype.

(Cadavid et al., 2000)

Comments

Allelic series of phenotypic severity: lqf^ARI >= lqf^AG > lqf^bE25 > lqf^bE248 > lqf^S011027.

(Tian et al., 2004)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

lqf^AG

(Cho and Fischer, 2011)

Name Synonyms

Secondary FlyBase IDs

References (3)

Report Sections

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