FB2026_02 , released June 18, 2026
Allele: Dmel\eyunspecified
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General Information
Symbol
Dmel\eyunspecified
Species
D. melanogaster
Name
FlyBase ID
FBal0104629
Feature type
allele
Associated gene
Dmel\ey
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Cytology
    Description

    FlyBase curator comment: this entry is used to capture phenotypic information when the particular allele (or allele combination) used by the author could not be determined but the context of the experiment suggests that the phenotype being described is some kind of loss of function.

    (FlyBase Curators, 2025-)
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        Mutational inactivation of ey results in moderate defects in the larval mushroom bodies. Mutations in ey abolish all the neuropil structures of the pupal mushroom bodies. The ellipsoid body is also disrupted.

        (Kurusu et al., 2000)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Phenotype Manifest In
        Enhanced by
        Statement
        Reference

        eyunspecified has lobe of mushroom body & larval mushroom body phenotype, enhanceable by Df(2L)dac-4

        (Kurusu et al., 2000)

        eyunspecified has adult mushroom body alpha-lobe | P-stage phenotype, enhanceable by Df(2L)dac-4

        (Kurusu et al., 2000)
        Suppressor of
        Statement
        Reference

        eyunspecified is a suppressor of eye phenotype of Scer\GAL4GMR.PF, nejΔBHQ.UAS

        (Anderson et al., 2005)
        Additional Comments
        Genetic Interactions
        Statement
        Reference

        The mushroom body defects of eyunspecified animals are enhanced by the addition of Df(2L)dac-4; most parts of the peduncles and lobes show clear symptoms of neural degeneration including significant degeneration of the αL-lobe in many cases.

        (Kurusu et al., 2000)
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (0)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (1)
        Reported As
        Symbol Synonym
        eyunspecified
        Name Synonyms
        Secondary FlyBase IDs
          References (5)