FlyBase Aberration Report: Dmel\Df(2L)dac-4

General Information

Symbol

Df(2L)dac-4

Species

D. melanogaster

Name

FlyBase ID

FBab0023581

Feature type

chromosomal_deletion

Also Known As

dac⁴, dac4

Computed Breakpoints include

Features within 35F12--36A8 (Estimated cytology)

Genomic Maps

JBrowse

Sequence coordinates

2L:16,376,738..16,376,738 (Df(2L)dac-4:bk1)

(Daines et al., 2009)

2L:16,638,995..16,638,995 (Df(2L)dac-4:bk2)

(Daines et al., 2009)

Member of large scale dataset(s)

Nature of Aberration

Cytological Order

Progenitor

Mutagen

Class of aberration (relative to wild type)

chromosomal_deletion

Class of aberration (relative to progenitor)

Breakpoints

Causes alleles

Carries alleles

Transposon Insertions

Formalized genetic data

Genetic mapping information

Comments

The breakpoints of the deletion ( 2L:16376738 and 2L:16638995 ) are not ligated together, but are separated by a 320bp sequence. portions of this 320bp sequence map in small blocks to multiple chromosomes making it difficult to infer the origin of the inserted sequence.

(Daines et al., 2009)

Comments on Cytology

Small deletion that removes the major band at 36A, and encompassing the entire dac locus.

(Mardon et al., 1994)

Sequence Crossreferences

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

Gene Deletion and Duplication Data

Genes Deleted / Disrupted

Complementation Data

Completely deleted / disrupted

dac

(Mardon et al., 1994)

Partially deleted / disrupted

Molecular Data

Completely deleted

Partially deleted

Genes NOT Deleted / Disrupted

Complementation Data

Molecular Data

Genes Duplicated

Complementation Data

Completely duplicated

Partially duplicated

Molecular Data

Completely duplicated

Partially duplicated

Genes NOT Duplicated

Complementation Data

Molecular Data

Affected Genes Inferred by Location (19)

Related Comments

Phenotypic Data

In combination with other aberrations

NOT in combination with other aberrations

Df(2L)dac-4 heterozygotes do not exhibit any size alterations or roughness in eyes when compared to control adults.

(Hoang et al., 2010)

The number of SE2 neurons is normal in Df(2L)dac-4 mutant animals.

(Losada-Pérez et al., 2010)

In Df(2L)dac-4 mutants the neuropils of the mushroom bodies are disrupted. Occasionally ectopic projections of peduncles are observed.

(Kurusu et al., 2000)

In 10% of larvae the dorsal lobes of the mushroom body are unilaterally reduced in diameter. The dorsal lobe can be unusually slanted and various regions of the mushroom body neuropile are widened.

(Noveen et al., 2000)

Mutant clones in the eye disc that do not include the posterior margin give rise to ommatidia. Posterior clones fail to develop into retinal tissue. Dominantly enhances the mutant eye phenotye of hh^bar3.

(Mardon et al., 1994)

Stocks (0)

Notes on Origin

Discoverer

Balancer / Genotype Variants of the Aberration

Separable Components

Other Comments

Synonyms and Secondary IDs (4)

Reported As

Symbol Synonym

Df(2L)dac-4

dac4

(Eade et al., 2012, Noveen et al., 2000)

dac⁴

(Clarembaux-Badell et al., 2022, Atallah et al., 2014, Herrero et al., 2014, Hoang et al., 2010, Losada-Pérez et al., 2010, Daines et al., 2009, Furukubo-Tokunaga et al., 2009, Baumgardt et al., 2007, Herrero et al., 2007, Mahoney et al., 2006, Anderson et al., 2005, Martini and Davis, 2005, Miguel-Aliaga et al., 2004, Tavsanli et al., 2004, Chu et al., 2002, Dong et al., 2002, Dong et al., 2001, Martini et al., 2000, Mardon et al., 1994)

dachshund⁴

(Kurusu et al., 2009)

Name Synonyms

Secondary FlyBase IDs

FBal0104661
FBal0125086

References (24)

Report Sections

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