FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Tpr2EU3220
Open Close
General Information
Symbol
Dmel\Tpr2EU3220
Species
D. melanogaster
Name
FlyBase ID
FBal0104705
Feature type
allele
Associated gene
Dmel\Tpr2
Associated Insertion(s)
P{EP}Tpr2EU3220
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Kazemi-Esfarjani and Benzer, 2000)
Progenitor genotype
Associated Insertion(s)
P{EP}Tpr2EU3220
Cytology
Description

P{EP} insertion 649bp 5' of the open reading frame.

(Kazemi-Esfarjani and Benzer, 2000)
Allele components
Component
Use(s)
Inserted element
P{EP}
Regulatory region(s)
UAS
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 1 )
      Disease
      Interaction
      References
      ameliorates  neurodegenerative disease
      modeled by Zzzz\CAG127Q.UAS.Tag:HA
      (Kazemi-Esfarjani and Benzer, 2000)
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Suppresses of the eye degeneration phenotype caused by expression of Zzzz\CAG127Q.Scer\UAS.T:Ivir\HA1 under the control of Scer\GAL4GMR.PF; external structure and pigmentation is improved. There is some improvement of internal retinal structure (some degeneration is seen).

      (Kazemi-Esfarjani and Benzer, 2000)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer

      Selected as: a suppressor of the eye degeneration phenotype caused by expression of Zzzz\CAG127Q.Scer\UAS.T:Ivir\HA1 under the control of Scer\GAL4GMR.PF.

      (Kazemi-Esfarjani and Benzer, 2000)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      EU3220
      (Kazemi-Esfarjani and Benzer, 2000)
      Tpr2EU3220
      Name Synonyms
      Secondary FlyBase IDs
        References (1)