FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\bcdR54A
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General Information
Symbol
Dmel\bcdR54A
Species
D. melanogaster
Name
FlyBase ID
FBal0105071
Feature type
allele
Associated gene
Dmel\bcd
Associated Insertion(s)
Carried in Construct
P{bcdR54A}
Key Links
Transgenic product class
missense_variant
(Niessing et al., 2000)
Mutagen
Nature of the Allele
Transgenic product class
missense_variant
(Niessing et al., 2000)
Mutagen
in vitro construct
(Niessing et al., 2000)
Progenitor genotype
bcd+t8.7
(Niessing et al., 2000)
Carried in construct
P{bcdR54A}
Cytology
Description

R to A amino acid replacement at position 54 in helix III of the bcd homeodomain.

(Niessing et al., 2000)
Allele components
Component
Use(s)
Regulatory region(s)
bcd
Encoded product / tool
bcd
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Partially rescues

      bcdR54A partially rescues bcd6

      (Niessing et al., 2000)
      Comments

      Partially rescues the phenotype of embryos derived from bcd6 females; at 18oC the embryos develop a normal segmentation pattern and give rise to normal-looking fertile adults. At 29oC, most embryos die as unhatched larvae with a strong head defect (although segmentation is normal).

      (Niessing et al., 2000)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      bcdR54A
      Name Synonyms
      Secondary FlyBase IDs
        References (1)