FlyBase Allele Report: Dmel\sc[t5'eye]

General Information

Symbol

Dmel\sc^t5'eye

Species

D. melanogaster

Name

FlyBase ID

FBal0117361

Feature type

allele

Associated gene

Dmel\sc

Associated Insertion(s)

Carried in Construct

P{5'eye-sc}

Key Links

Allele class

Mutagen

in vitro construct - regulatory fusion

Nature of the Allele

Allele class

Mutagen

in vitro construct - regulatory fusion

(Sun et al., 2000)

Mutations Mapped to the Genome

Type

Location

Additional Notes

References

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Progenitor genotype

Carried in construct

P{5'eye-sc}

Cytology

Nature of the lesion

Statement

Reference

Construct: ato upstream sequences containing the eye enhancer are fused upstream of a 2.1kb sc fragment.

(Sun et al., 2000)

Allele components

Product class / Tool use(s)

Encoded product / tool

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressor of

Statement

Reference

sc^t5'eye is a suppressor | partially of visible phenotype of ato¹, ato^t3'F.5.8

(Sun et al., 2000)

NOT Suppressor of

Statement

Reference

sc^t3'F.5.8/sc^t5'eye is a non-suppressor of visible phenotype of ato¹

(Sun et al., 2000)

sc^t5'eye is a non-suppressor of visible phenotype of ato¹

(Sun et al., 2000)

Phenotype Manifest In

Suppressor of

Statement

Reference

sc^t5'eye is a suppressor | partially of ommatidium phenotype of ato¹, ato^t3'F.5.8

(Sun et al., 2000)

NOT Suppressor of

Statement

Reference

sc^t5'eye is a non-suppressor of photoreceptor cell R8 phenotype of ato¹, ato^t3'F.5.8

(Sun et al., 2000)

sc^t3'F.5.8/sc^t5'eye is a non-suppressor of ommatidium phenotype of ato¹

(Sun et al., 2000)

sc^t3'F.5.8/sc^t5'eye is a non-suppressor of photoreceptor cell R8 phenotype of ato¹

(Sun et al., 2000)

sc^t5'eye is a non-suppressor of ommatidium phenotype of ato¹

(Sun et al., 2000)

sc^t5'eye is a non-suppressor of photoreceptor cell R8 phenotype of ato¹

(Sun et al., 2000)

Additional Comments

Genetic Interactions

Statement

Reference

The addition of two copies of either or both sc^t3'F.5.8 and sc^t5'eye does not restore any boss-expressing R8 photoreceptors or ommatidia.

The addition of ato^t3'F.5.8 and sc^t5'eye to ato¹ flies does restore significant numbers of ommatidia but does not restore R8 receptors, even though either transgene alone gives no rescue/suppression of this ato¹ phenotype. This leads to an unusual arrangement of photoreceptors in the ommatidia. Many of these ommatidia contain fewer than eight photoreceptors, and most of the remaining photoreceptors resemble outer photoreceptors by their positions and the large size of their rhabdomeres.

(Sun et al., 2000)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

sc^t5'eye

Name Synonyms

Secondary FlyBase IDs

References (1)

Report Sections

Open Close