FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Cdk5αUAS.Tag:MYC
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General Information
Symbol
Dmel\Cdk5αUAS.Tag:MYC
Species
D. melanogaster
Name
FlyBase ID
FBal0117902
Feature type
allele
Associated gene
Dmel\Cdk5α
Associated Insertion(s)
Carried in Construct
P{UAS-Dp35-Myc}
Also Known As
UAS-p35
Key Links
Transgenic product class
cDNA
(Connell-Crowley, 2000)
wild_type
(Connell-Crowley, 2000)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Connell-Crowley, 2000)
wild_type
(Connell-Crowley, 2000)
Mutagen
in vitro construct
(Connell-Crowley, 2000)
Progenitor genotype
Carried in construct
P{UAS-Dp35-Myc}
Cytology
Description

UAS sequences drive expression of the Cdk5α cDNA tagged with Tag:MYC.

(Connell-Crowley, 2000)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
Cdk5α
Tagged with
Tag:MYC
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Cdk5αScer\UAS.T:Hsap\MYC driven by Scer\GAL4GMR.PF causes a slight rough eye phenotype. Expression of Cdk5αScer\UAS.T:Hsap\MYC driven by Scer\GAL4unspecified has no effect on neuron cell fate.

      (Connell-Crowley et al., 2000)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      When Cdk5αScer\UAS.T:Hsap\MYC and Cdk5Scer\UAS.T:Zzzz\FLAG are driven by Scer\GAL4GMR.PF, a severely disrupted eye morphology results. In embryos, the proportion seen with nervous system defects increases. The defects seen in the embryonic nervous system when two copies of P{UAS-Dp35-Myc} are driven by Scer\GAL4unspecified are suppressed by two copies of P{UAS-Cdk5K33A-FLAG}.

      (Connell-Crowley et al., 2000)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Cdk5αScer\UAS.T:Hsap\MYC
      Cdk5αUAS.Tag:MYC
      Name Synonyms
      Secondary FlyBase IDs
        References (5)