FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\decfc177
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General Information
Symbol
Dmel\decfc177
Species
D. melanogaster
Name
FlyBase ID
FBal0118270
Feature type
allele
Associated gene
Dmel\dec
Associated Insertion(s)
Carried in Construct
P{fc177}
Key Links
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Nogueron et al., 2000)
Progenitor genotype
Carried in construct
P{fc177}
Cytology
Description

Consists of a mixture of fragments derived from dec-1 cDNA and genomic clones. Includes coding sequence for the fc177 transcript along with 1.9kb of 5' and 1 kb of 3' dec-1 flanking DNA. The fc125 5' splice has also been mutated (AGGTTAGC to ACTGCAGC)to maximise production of fc177.

(Nogueron et al., 2000)
Allele components
Component
Use(s)
Regulatory region(s)
dec
Encoded product / tool
dec
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      decfc177 rescues dec4

      (Nogueron et al., 2000)
      Partially rescues

      decfc177 partially rescues dec29

      (Mauzy-Melitz and Waring, 2003)

      decfc177 partially rescues decct4b1/dec29

      (Mauzy-Melitz and Waring, 2003)
      Comments

      The addition of dec-1fc177 to dec-129 homozygous or dec-129/dec-1ct4b1 animals rescues the egg shell morphology phenotypes of dec-129, but not female sterility, and eggshells remain compromised.

      (Mauzy-Melitz and Waring, 2003)

      dec-14, dec-1fc177 animals are fertile and display wild-type eggshell morphology.

      (Nogueron et al., 2000)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      dec-1fc177
      decfc177
      Name Synonyms
      Secondary FlyBase IDs
        References (2)