FlyBase Allele Report: Dmel\bgcn[z2-1748]

General Information

Symbol

Dmel\bgcn^z2-1748

Species

D. melanogaster

Name

FlyBase ID

FBal0118311

Feature type

allele

Associated gene

Dmel\bgcn

Associated Insertion(s)

Carried in Construct

Key Links

Genomic Maps

JBrowse

Allele class

Mutagen

Nature of the Allele

Allele class

Mutagen

Progenitor genotype

Cytology

Description

Amino acid replacement: R214term.

(Ohlstein et al., 2000)

Nucleotide substitution: C?T.

(Ohlstein et al., 2000)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

point_mutation

2R:23,858,060..23,858,060 [-]

Nucleotide change:

C23858060T

Reported nucleotide change:

C?T

Amino acid change:

R214term | bgcn-PA; R214term | bgcn-PB

Reported amino acid change:

R214term

(Ohlstein et al., 2000)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

female sterile (with bgcn¹)

(Zinshteyn and Barbash, 2022)

female sterile | recessive

(Ohlstein et al., 2000)

male sterile | recessive

(Ohlstein et al., 2000)

viable

(Ohlstein et al., 2000)

Phenotype Manifest In

germline cell

(Ohlstein et al., 2000)

gonad

(Ohlstein et al., 2000)

Detailed Description

Statement

Reference

Homozygotes have germline tumours in their gonads.

(Ohlstein et al., 2000)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

NOT suppressed by

Statement

Reference

bgcn^z2-1748/bgcn¹ has female sterile phenotype, non-suppressible by stwl^j6C3/Df(3L)Exel6122

(Zinshteyn and Barbash, 2022)

NOT Suppressor of

Statement

Reference

bgcn^z2-1748/bgcn¹ is a non-suppressor of female sterile phenotype of stwl^j6C3/Df(3L)Exel6122

(Zinshteyn and Barbash, 2022)

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

bgcn^z2-1748

(Zinshteyn and Barbash, 2022)

Name Synonyms

Secondary FlyBase IDs

References (2)

Report Sections

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