FB2026_02 , released June 18, 2026
Allele: Dmel\bgcnhs.PO
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General Information
Symbol
Dmel\bgcnhs.PO
Species
D. melanogaster
Name
heat shock construct of Ohlstein
FlyBase ID
FBal0118314
Feature type
allele
Associated gene
Dmel\bgcn
Associated Insertion(s)
Carried in Construct
P{hs-bgcn.O}
Key Links
Transgenic product class
cDNA
(Ohlstein et al., 2000)
wild_type
(Ohlstein et al., 2000)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Ohlstein et al., 2000)
wild_type
(Ohlstein et al., 2000)
Mutagen
in vitro construct
(Ohlstein et al., 2000)
Progenitor genotype
Carried in construct
P{hs-bgcn.O}
Cytology
Description

An Hsp70 promoter drives expression of a full length bgcn cDNA.

(Ohlstein et al., 2000)
Allele components
Component
Use(s)
Regulatory region(s)
Hsp70
Encoded product / tool
bgcn
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      8 days after the initial heat shock, flies expressing bgcnhs.PO contain a normal array of developing cysts and germline stem cells can be identified by single, spherical fusomes.

      (Ohlstein et al., 2000)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Partially rescues

      bgcnhs.PO partially rescues bgcn1

      (Ohlstein et al., 2000)
      Comments

      Homozygous bgcn1 females expressing bgcnhs.PO using heat shock have maturing egg chambers and germaria organised into morphologically distinct regions 1,2 and 3 that are formed as cysts are assembled. Ovaries in older animals also have egg chambers with 15 nurse cells and one yolk-accumulating oocyte. The females are not fertile. Late stage egg chambers (stage 12 and later) contain small oocytes, misshapen follicle cell layers and are not laid. Spermatogenesis has not been rescued in homozygous bgcn1 males expressing bgcnhs.PO using heat shock.

      (Ohlstein et al., 2000)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      bgcnhs.PO
      Name Synonyms
      heat shock construct of Ohlstein
      (Ohlstein et al., 2000)
      Secondary FlyBase IDs
        References (1)