FlyBase Allele Report: Dmel\sls[C995]

General Information

Symbol

Dmel\sls^C995

Species

D. melanogaster

Name

FlyBase ID

FBal0118441

Feature type

allele

Associated gene

Dmel\sls

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

Mutagen

ethyl methanesulfonate

Nature of the Allele

Allele class

Mutagen

ethyl methanesulfonate

(Zhang et al., 2000)

Progenitor genotype

Cytology

Description

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal locomotor behavior | embryonic stage | recessive

(Zhang et al., 2000)

lethal - all die during embryonic stage | recessive

(Zhang et al., 2000)

some die during embryonic stage | recessive

(Zhang et al., 2000)

Phenotype Manifest In

visceral muscle fiber | embryonic stage

(Zhang et al., 2000)

Detailed Description

Statement

Reference

Mutant embryos show grossly normal morphology, normal segmentation, normal epidermal denticle belts and normal patterning of the neuromusculature. They show greatly reduced movement compared to wild-type. Mature embryos show striking defects in individual muscle fibre morphology.

(Zhang et al., 2000)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Fails to complement

sls^B170

(Zhang et al., 2000)

sls^B173

(Zhang et al., 2000)

sls^B247

(Zhang et al., 2000)

sls^B68

(Zhang et al., 2000)

sls^C872

(Zhang et al., 2000)

sls^S000201

(Zhang et al., 2000)

sls^j1D7

(Zhang et al., 2000)

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

Selected as: an embryonic lethal mutation with abnormal locomotory behaviour but grossly normal neuromusculature.

(Zhang et al., 2000)

Comments

Based on the lethal stage and antibody staining, sls alleles form the series: sls^S000201 (weakest), sls^B173, sls^C995, sls^j1D7, sls^B68, sls^C872 (strongest).

(Zhang et al., 2000)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

Ket^C995

(Zhang et al., 2000)

sls^C995

Name Synonyms

Secondary FlyBase IDs

References (1)

Report Sections

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