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General Information
Symbol
Dmel\Adf1hs.PD
Species
D. melanogaster
Name
heat shock construct of DeZazzo
FlyBase ID
FBal0119716
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

A 1603bp Adf1 cDNA fragment is inserted driven by a Hsp70 promoter. This fragment spans the region from 133bp upstream of the start codon to 709 bp downstream of the stop codon.

Allele components
Product class / Tool use(s)
Regulatory region(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

When raised at 25oC olfactory memory is lower than normal. However 309 minute heatshock treatments do not appear to have any effect on olfactory memory. Miniature excitatory junctional current (mEJC) amplitude is normal in mutants, though an increase in mEJC frequency is occasionally seen. Adf1hs.PD mutants grown at 21oC have more synaptic boutons than seen in wild-type.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments

Leaky expression of Adf1hs.PD can rescue the lethality of Adf1nal at 18oC or 25oC. When flies raised at 18oC are shifted to 25oC for the first three days after eclosion, the memory defect is also rescued.

Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
Adf1hs.PD
Name Synonyms
heat shock construct of DeZazzo
Secondary FlyBase IDs
    References (1)