FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Lk6EP886
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General Information
Symbol
Dmel\Lk6EP886
Species
D. melanogaster
Name
FlyBase ID
FBal0120766
Feature type
allele
Associated gene
Dmel\Lk6
Associated Insertion(s)
P{EP}Lk6EP886
Carried in Construct
Also Known As
EP(3)0886
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Gene Disruption Project members, 2001-, Huang and Rubin, 2000)
Progenitor genotype
Associated Insertion(s)
P{EP}Lk6EP886
Cytology
Description
Allele components
Component
Use(s)
Inserted element
P{EP}
Regulatory region(s)
UAS
Mutations Mapped to the Genome
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Enhancer of
      Statement
      Reference

      Lk6EP886/Scer\GAL4hs.2sev is an enhancer of visible phenotype of ksr::torΔNksr.hs.sev

      (Huang and Rubin, 2000)
      Suppressor of
      Statement
      Reference

      Lk6EP886/Scer\GAL4hs.2sev is a suppressor of visible phenotype of Ras85DV12.sev

      (Huang and Rubin, 2000)
      Phenotype Manifest In
      Enhancer of
      Suppressor of
      Statement
      Reference

      Lk6EP886/Lk6[+] is a suppressor of ovary phenotype of bru1QB/bru1PD

      (Yan and Macdonald, 2004)

      Lk6EP886/Lk6[+] is a suppressor of ovary phenotype of bru1QB

      (Yan and Macdonald, 2004)

      Lk6EP886/Scer\GAL4hs.2sev is a suppressor of eye phenotype of Ras85DV12.sev

      (Huang and Rubin, 2000)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Expression of Lk6EP886 under the control of Scer\GAL4mat.αTub67C.T:Hsim\VP16 enhances the ovary phenotype of aretPD/aretQB females (oogenesis arrests at 3), while in the absence of an Scer\GAL4 driver, Lk6EP886 suppresses the ovary phenotype of aretPD/aretQB females (oogenesis arrests at stage 9). The hatch rate of embryos derived from aretPA/aretPD females is increased from 3% to 14% in the presence of Lk6EP886/+. aretPD/aretQB eIF-4ES251D ; Lk6EP886/+ females arrest oogenesis at the same stage (stage 9) as aretPD/aretQB ; Lk6EP886/+ females.

      (Yan and Macdonald, 2004)

      Very strong enhancer of ksr::torΔNksr.hs.sev and strong suppressor of Ras85DV12.sev, when expression is driven by Scer\GAL4hs.2sev.

      (Huang and Rubin, 2000)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      Lk6EP886
      Name Synonyms
      Secondary FlyBase IDs
        References (3)