FB2026_02 , released June 18, 2026
Allele: Dmel\Indy159
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General Information
Symbol
Dmel\Indy159
Species
D. melanogaster
Name
FlyBase ID
FBal0120793
Feature type
allele
Associated gene
Dmel\Indy
Associated Insertion(s)
P{lacW}Indy159
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Rogina et al., 2000)
Progenitor genotype
Associated Insertion(s)
P{lacW}Indy159
Cytology
Description

P{lacW} insertion within a 1360 element that is present in the first intron of Indy, just upstream of the putative translational start site (the 1360 element is present in the same position in wild-type animals).

(Rogina et al., 2000)
Allele components
Component
Use(s)
Inserted element
P{lacW}
Encoded product / tool
lacZ
Tagged with
Tag:NLS(P)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Heterozygotes show an increase in mean life-span to 69 days (compared to 37 days for controls) at 25oC, an extension in mean life-span of 87%. Extension of 1% maximal life-span is greater than 45%. At 18oC, the increase in mean life-span in mutants approaches 100% and the increase in 1% maximum life-span approaches 50% compared to controls.

      (Rogina et al., 2000)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Indy159
      (Rogina et al., 2000)
      Indy159
      Name Synonyms
      Secondary FlyBase IDs
        References (1)