FB2026_02 , released June 18, 2026
Allele: Dmel\robo27
Open Close
General Information
Symbol
Dmel\robo27
Species
D. melanogaster
Name
FlyBase ID
FBal0121556
Feature type
allele
Associated gene
Dmel\robo2
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class

loss of function allele

Mutagen
Nature of the Allele
Allele class

loss of function allele

(Rajagopalan et al., 2000)
Mutagen
ethyl methanesulfonate
(Rajagopalan et al., 2000)
Progenitor genotype
robo2EP2582
(Rajagopalan et al., 2000)
Cytology
Description

Amino acid replacements are a revision of the data reported in FBrf0132258. They are numbered relative to the 1406 amino acid residue predicted protein.

(Dickson, 2001.3.14)

Amino acid replacement: W825term.

(Dickson, 2001.3.14)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
point_mutation
2L:1,387,460..1,387,460 [-]
Nucleotide change:

G1387460A

Amino acid change:

W882term | robo2-PA; W882term | robo2-PB

Reported amino acid change:

W882term

Comment:

G to A nucleotide change at the second or third position of the wild type Trp codon leads to a nonsense mutation (exact site of mutation unspecified). The mutation was annotated at the second base of the codon.

(Rajagopalan et al., 2000)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      learobo2-7
      robo27
      (Dickson, 2001.3.14, Rajagopalan et al., 2000)
      Name Synonyms
      Secondary FlyBase IDs
        References (3)