FB2026_02 , released June 18, 2026
Allele: Dmel\ptc47
Open Close
General Information
Symbol
Dmel\ptc47
Species
D. melanogaster
Name
FlyBase ID
FBal0121580
Feature type
allele
Associated gene
Dmel\ptc
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Strutt et al., 2001)
Progenitor genotype
Cytology
Description

The premature stop codon is in between the eighth and ninth transmembrane domains.

(Strutt et al., 2001)

Amino acid replacement: ??term.

(Strutt et al., 2001)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      All flies carrying ptctuf-1 in trans to ptc47 have severely reduced, rough eyes, a highly enlarged head vertex (ocellar triangle, fronto-orbital plate and frons), outgrowths of head cuticle and large numbers of missing, misplaced or ectopic head bristles. ptc559.1/ptc47 flies have mildly reduced eyes, a normal sized head vertex and low incidences of head cuticle outgrowths and ectopic or misplaced head bristles. They also occasionally lack one or both antennae.

      (Thomas and Ingham, 2003)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Suppressor of
      Statement
      Reference

      ptc47/ptctuf-1 is a suppressor of eye phenotype of hhbar3

      (Thomas and Ingham, 2003)
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      ptc47
      Name Synonyms
      Secondary FlyBase IDs
        References (3)