FB2026_02 , released June 18, 2026
Allele: Dmel\E(rst)H253H253
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General Information
Symbol
Dmel\E(rst)H253H253
Species
D. melanogaster
Name
FlyBase ID
FBal0122228
Feature type
allele
Associated gene
E(rst)H253
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl nitrosourea
(Tanenbaum et al., 2000)
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Enhancer of
      Statement
      Reference

      E(rst)H253H253 is an enhancer of eye phenotype of rstirreC1

      (Tanenbaum et al., 2000)

      E(rst)H253H253 is an enhancer of ommatidium phenotype of rstirreC1

      (Tanenbaum et al., 2000)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Dominant enhancer of the rough eye phenotype of In(1)rst3. The severity of the rstirreC1 rough eye phenotype is increased by E(rst)H253H253.

      (Tanenbaum et al., 2000)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer

      Selected as: a dominant enhancer of the rough eye phenotype of In(1)rst3. The "H253" line is homozygous lethal, but it is not yet known whether the lethality maps to the same location as the modifier of the In(1)rst3 phenotype.

      (Tanenbaum et al., 2000)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      E(rst)H253H253
      H253
      (Tanenbaum et al., 2000)
      Name Synonyms
      Secondary FlyBase IDs
        References (1)