FB2026_02 , released June 18, 2026
Allele: Dvir\nonA+t12.5
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General Information
Symbol
Dvir\nonA+t12.5
Species
D. virilis
Name
FlyBase ID
FBal0122280
Feature type
allele
Associated gene
Dvir\nonA
Associated Insertion(s)
Carried in Construct
P{Dvir\Gpi1+t12.5}
Transgenic product class
genomic_DNA
(Campesan et al., 2001)
wild_type
(Campesan et al., 2001)
Mutagen
Nature of the Allele
Transgenic product class
genomic_DNA
(Campesan et al., 2001)
wild_type
(Campesan et al., 2001)
Mutagen
in vitro construct
(Campesan et al., 2001)
Progenitor genotype
Carried in construct
P{Dvir\Gpi1+t12.5}
Cytology
Description

Construct: 12.5kb genomic fragment containing both Dvir\Gpi1 and Dvir\nonA coding sequences.

(Campesan et al., 2001)
Allele components
Component
Use(s)
Encoded product / tool
Dvir\nonA
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      D.melanogaster flies carrying Dvir\nonA+t12.5 in a nonA+ background have a normal optomotor response.

      (Campesan et al., 2001)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressor of
      Statement
      Reference

      Dvir\nonA+t12.5 is a suppressor of abnormal optomotor response phenotype of nonA9e2-10

      (Campesan et al., 2001)
      Other
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference

      P{Dvir\Gpi1+t12.5} suppresses the lethality associated with T(1;4)9e2-10 (which causes the alleles l(1)14Ca9e2-10 and nonA9e2-10) when transformed into D.melanogaster. The ERG of T(1;4)9e2-10/Y flies carrying P{Dvir\Gpi1+t12.5} is normal.

      (Campesan et al., 2001)

      The song characteristics of D.melanogaster nonA9e2-10/Y males carrying Dvir\nonA+t12.5 show D.virilis-like features while maintaining indicators of "normal" D.melanogaster song output such as the subtle change in PF (intrapulse frequency) during a song burst. The flies also appear to have a D.virilis-like shorter IPI (interpulse interval), even though the other characteristics of the song pulses that have been measured should, indirectly, lead to a longer IPI, suggesting that Dvir\nonA+t12.5 is playing an active role in reducing IPIs.

      (Campesan et al., 2001)
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      Dvir\nonA+t12.5
      Name Synonyms
      Secondary FlyBase IDs
        References (2)