FB2026_02 , released June 18, 2026
Allele: Dmel\Rokunspecified
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General Information
Symbol
Dmel\Rokunspecified
Species
D. melanogaster
Name
FlyBase ID
FBal0122915
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Cytology
    Description

    FlyBase curator comment: this entry is used to capture phenotypic information when the particular allele (or allele combination) used by the author could not be determined but the context of the experiment suggests that the phenotype being described is some kind of loss of function.

    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    Variant Molecular Consequences
    Associated Sequence Data
    DNA sequence
    Protein sequence
     
    Expression Data
    Reporter Expression
    Additional Information
    Statement
    Reference
     
    Marker for
    Reflects expression of
    Reporter construct used in assay
    Human Disease Associations
    Disease Ontology (DO) Annotations
    Models Based on Experimental Evidence ( 0 )
    Disease
    Evidence
    References
    Modifiers Based on Experimental Evidence ( 0 )
    Disease
    Interaction
    References
    Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
     
    Disease-implicated variant(s)
     
    Phenotypic Data
    Phenotypic Class
    Phenotype Manifest In
    Detailed Description
    Statement
    Reference

    rokunspecified embryos display defects in cellularisation including an irregular, wavy cellularisation front. The nuclei of rokunspecified mutant embryos have striking defects, including displacement into the interior of the embryo leaving reduced numbers at the cortex, with the remaining nuclei often being of increased size and irregular morphology. Despite these defects, many embryos complete cellularisation. At later stages of gastrulation, the outer layer of rokunspecified mutant embryos becomes multilayered and irregular (compared to a single-layered epithelium in wild-type), containing large, often rounded cells.

    External Data
    Interactions
    Show genetic interaction network for Enhancers & Suppressors
    Phenotypic Class
    NOT Suppressor of
    Statement
    Reference

    Rokunspecified is a non-suppressor of abnormal planar polarity | heat sensitive phenotype of fzI.hs

    Phenotype Manifest In
    NOT Suppressor of
    Statement
    Reference

    Rokunspecified is a non-suppressor of wing hair phenotype of fzI.hs

    Additional Comments
    Genetic Interactions
    Statement
    Reference
    Xenogenetic Interactions
    Statement
    Reference
    Complementation and Rescue Data
    Comments
    Images (0)
    Mutant
    Wild-type
    Stocks (0)
    Notes on Origin
    Discoverer
    External Crossreferences and Linkouts ( 0 )
    Synonyms and Secondary IDs (2)
    Reported As
    Symbol Synonym
    Rokunspecified
    rokunspecified
    Name Synonyms
    Secondary FlyBase IDs
      References (3)