Drok, ROCK, Rho-associated kinase, DRhk, DRho-kinase
Rho-kinase - plays a role in planar cell polarity - required for tissue morphogenesis in diverse compartments of the egg chamber during oogenesis - directs Bazooka/Par-3 planar polarity during Drosophila axis elongation
Low-frequency RNA-Seq exon junction(s) not annotated.
Gene model reviewed during 5.50
6.259 (longest cDNA)
None of the polypeptides share 100% sequence identity.
1390 (aa); 160 (kD predicted)
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Rok using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signalsView Dmel\Rok in GBrowse 2
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
dsRNA directed against this gene causes defects in cytokinesis when tested in an RNAi screen in S2 cells.
dsRNA made from templates generated with primers directed against this gene tested in RNAi screen for effects on Kc167 and S2R+ cell morphology.
dsRNA made from templates generated with primers directed against this gene is tested in an RNAi screen for effects on actin-based lamella formation.