PP1β9C, PP1, PP1β, PP1 9C, PP1c
1.584 (compiled cDNA)
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\flw using the Feature Mapper tool.
mRNAs of 2.7, 2.9, 4.1 and 4.6 kb were detected, with the 2.9 kb most abundant. The mRNAs were detected in all developmental stages, but were less abundant in embryos and larvae.
GBrowse - Visual display of RNA-Seq signalsView Dmel\flw in GBrowse 2
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Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Source for merge of: flw Pp1β-9C
Source for merge of: Pp1β-9C CG2096
Source for merge of: flw l(1)G0172
Source for merge of: flw anon-WO03040301.120
Source for merge of: flw CG15305
Annotations CG2096 and CG15305 merged as CG2096 in release 3 of the genome annotation.
Source for merge of flw anon-WO03040301.120 was sequence comparison ( date:051113 ).
flw is not allelic to gmp.
flw limits ring canal constriction during germline cyst formation in females.
Isolated from a Drosophila head cDNA library, using a rabbit muscle PP-1α cDNA as a probe.
Fate mapping of flw mutants suggests their primary site of action is in the fat body.
Wings held in lateral position, instead of dorsally and parallel to substrate as in wild type; thorax has darkened longitudinal stripe; anterior scutellar bristles sometimes missing or doubled; eyes bulging and slightly roughened; head compressed; third antennal joint shortened; unable to fly; jumping ability poor; fibrillar muscles of thorax (dorsoventrals, dorsolongitudinals) are variably abnormal, ranging from disorganized to missing; tergal depressor of trochanter jump muscle is normal in light microscope; behavioral and muscular phenotypes affected by flw2 may be due to primary defect in muscle primordia, concluded from mosaic experiment (Deak, 1977); at least two flw alleles (flw3 and flw4) cause reduced amount of a particular protein from indirect flight muscles (same molecule as that affected by hdp, int, rsd and up mutations) (Deak et al., 1982).