CnnA14D, PP2B 14D, canA, calcineurin
Calcium-dependent protein serine/threonine phosphatase - negatively regulates Egf receptor signaling - calcineurin isoforms are involved in Drosophila toll immune signaling correcting calcineurin and GSK-3β signaling can prevent amyloid precursor protein-induced pathologies
4.5, 2.0 (northern blot)
Interacts with sra in a complex that contains CanA-14F.
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Pp2B-14D using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signalsView Dmel\Pp2B-14D in GBrowse 2
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Source for merge of: Pp2B-14D PpD33
The Pp2B-14D gene may have been derived from a related phosphoprotein phosphatase gene by retroposition and subsequent tandem duplication.
Source for merge of Pp2B-14D PpD33 was sequence comparison ( date:050803 ).