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General Information
Symbol
Dmel\Mef2X1
Species
D. melanogaster
Name
FlyBase ID
FBal0042670
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Mutagen
Nature of the Allele
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

Deficiency breakpoint breaks within the large intron that interrupts the 5' untranslated region of the Mef2 gene.

Caused by aberration
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 1 )
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Mef2X1/+ does not cause significant cardiac enlargement or reduced fractional shortening in adult hearts.

Embryonic lethal when heterozygous with Df(2R)520. Embryos exhibit lack of Mhc-expressing cells and lack of muscle fibres. Midgut morphogenesis and late heart differentiation are also defective.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Suppressor of
Statement
Reference
Phenotype Manifest In
Suppressor of
Statement
Reference
Additional Comments
Genetic Interactions
Statement
Reference

Mef2X1/+ rescues the cardiac enlargement and reduced fractional shortening phenotypes seen in flies expressing Pp2B-14Dact.tin.C.T:Zzzz\FLAG.

Mef2X1/+ rescues the cardiac enlargement and the reduced fractional shortening phenotype of flies expressing Pp2B-14Dact.Scer\UAS.T:Avic\GFP-EYFP under the control of Scer\GAL4tin.CΔ4.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (2)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (4)
References (9)