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General Information
Symbol
Scer\GAL4sr-md710
Species
S. cerevisiae
Name
FlyBase ID
FBal0120626
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
Stripe-Gal4, sr-GAL4, srGAL4
Allele class
Mutagen
    Nature of the Allele
    Expression Data
    Reporter Expression
    distribution deduced from reporter
    Stage
    Tissue/Position (including subcellular localization)
    Reference
    distribution deduced from reporter (Gal4 UAS)
    Stage
    Tissue/Position (including subcellular localization)
    Reference
    Additional Information
    Statement
    Reference

    To study tendon development, sr reporter expression was studied during leg development relative to and odd reporter, which is expressed at the segmental joints. The first tendon to develop is the long tendon of the tarsi that arises from cells coexpressing sr and odd at the T5/pretarsus boundary at early third instar. These cells invaginate and elongate into the tarsal cavity formed by the progressive evagination of the leg disc at the beginning of metamorphosis. By the end of leg development, they will form a long internal tube extending from pre-tarsus to femur with the apical pole facing the lumen. With a short delay, another cluster of tendon precursor cells is specified during the third instar at the femur/tibia boundary in the dorsal position. Subsequently, during early pupation, additional sr-positive clusters are specified along the five segmental pre-patterned odd-positive boundary rings. This indicates that odd/sr-positive tendon precursors are specified progressively following the leg proximodistal segmentation with odd expression preceding sr expression. N was observed to appear sequentially and precede sr expression.

    Drives expression in tendon cells.

    Expression is the same as that observed for the sr gene, and does not overlap with the expression pattern of ac or sc.

    Larval expression is observed in tendon cells.

    Pupal expression is observed in the attachment sites of the anterior dorsal medial muscles.

     
    Reporter construct used in assay
    Human Disease Associations
    Disease Ontology (DO) Annotations
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    Modifiers Based on Experimental Evidence ( 0 )
    Disease
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    Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
     
    Disease-implicated variant(s)
     
    Phenotypic Data
    Phenotypic Class
    Phenotype Manifest In
    Detailed Description
    Statement
    Reference
    External Data
    Interactions
    Show genetic interaction network for Enhancers & Suppressors
    Phenotypic Class
    Phenotype Manifest In
    Suppressed by
    Statement
    Reference
    Additional Comments
    Genetic Interactions
    Statement
    Reference
    Xenogenetic Interactions
    Statement
    Reference
    Complementation and Rescue Data
    Comments
    Images (0)
    Mutant
    Wild-type
    Stocks (1)
    Notes on Origin
    Discoverer
    External Crossreferences and Linkouts ( 0 )
    Synonyms and Secondary IDs (2)
    Reported As
    Symbol Synonym
    Scer\GAL4sr-md710
    Name Synonyms
    Secondary FlyBase IDs
      References (44)