FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\qsmF17fs
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General Information
Symbol
Dmel\qsmF17fs
Species
D. melanogaster
Name
FlyBase ID
FBal0367640
Feature type
allele
Associated gene
Dmel\qsm
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class

loss of function allele

Mutagen
Nature of the Allele
Allele class

loss of function allele

(Chu and Hayashi, 2021)
Mutagen
CRISPR/Cas9
(Chu and Hayashi, 2021)
Progenitor genotype
Cytology
Description

Five bp deletion in qsm results in a frameshift of the ORF at F17.

(Chu and Hayashi, 2021)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
point_mutation
2R:20,581,581..20,581,585 [-]
Comment:

Inferred coordinates of a 5bp deletion that results in a frameshift inf qsm at F17. The aa sequence of the predicted protein is MLLSMQMWRSLWLAALRISPGQRFPQGALFGGSDEG*

(Chu and Hayashi, 2021)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      qsmF17fs mutants exhibit epidermal invaginations or elevations on the notum at the muscle insertion sites of DLM (comma phenotype) and DVM (vortex phenotype), as well as a oblique wing. The anterior tendon cells of pupal DLMs show increased length.

      (Chu and Hayashi, 2021)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Enhanced by
      Statement
      Reference

      qsmF17fs has visible | adult stage phenotype, enhanceable by dpyov1

      (Chu and Hayashi, 2021)
      Suppressed by
      Enhancer of
      Statement
      Reference

      qsmF17fs/qsmF17fs is an enhancer of visible | adult stage phenotype of dpyov1

      (Chu and Hayashi, 2021)
      Other
      Phenotype Manifest In
      Enhanced by
      Statement
      Reference

      qsmF17fs has wing phenotype, enhanceable by dpyov1

      (Chu and Hayashi, 2021)

      qsmF17fs has notum phenotype, enhanceable by dpyov1

      (Chu and Hayashi, 2021)
      Suppressed by
      NOT suppressed by
      Statement
      Reference

      qsmF17fs has wing phenotype, non-suppressible by Scer\GAL4sr-md710/RokGD1522

      (Chu and Hayashi, 2021)

      qsmF17fs has wing phenotype, non-suppressible by Scer\GAL4sr-md710/RokKK107802

      (Chu and Hayashi, 2021)
      Enhancer of
      Statement
      Reference

      qsmF17fs/qsmF17fs is an enhancer of wing phenotype of dpyov1

      (Chu and Hayashi, 2021)

      qsmF17fs/qsmF17fs is an enhancer of notum phenotype of dpyov1

      (Chu and Hayashi, 2021)
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      qsmF17fs
      (Chu and Hayashi, 2021)
      Name Synonyms
      Secondary FlyBase IDs
        References (1)