FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\LrtUAS.EGFP
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General Information
Symbol
Dmel\LrtUAS.EGFP
Species
D. melanogaster
Name
FlyBase ID
FBal0241219
Feature type
allele
Associated gene
Dmel\Lrt
Associated Insertion(s)
Carried in Construct
P{UAS-Lrt.GFP}
Key Links
Transgenic product class
wild_type
(Wayburn and Volk, 2009)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Wayburn and Volk, 2009)
Mutagen
in vitro construct
(Wayburn and Volk, 2009)
Progenitor genotype
Carried in construct
P{UAS-Lrt.GFP}
Cytology
Description

UAS regulatory sequences drive expression of Lrt which is tagged at the C-terminal end with EGFP.

(Wayburn and Volk, 2009)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
Lrt
Tagged with
EGFP
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of LrtScer\UAS.T:Avic\GFP-EGFP under the control of Scer\GAL4sr-md710 results in an abnormal muscle phenotype in 70% of embryos; the dorsal longitudinal muscles stall close to a single segmental border and do not extend between two segmental borders in two to four segments. In 20% of these embryos, similar defects are also seen in the ventral longitudinal muscles.

      Expression of LrtScer\UAS.T:Avic\GFP-EGFP under the control of Scer\GAL4Mef2.PR does not result in a mutant muscle phenotype.

      (Wayburn and Volk, 2009)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Suppressed by
      Statement
      Reference

      LrtUAS.EGFP, Scer\GAL4sr-md710 has larval somatic muscle cell phenotype, suppressible by robo[+]/robo11

      (Wayburn and Volk, 2009)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      robo1/+ completely rescues the abnormal muscle phenotype caused by expression of LrtScer\UAS.T:Avic\GFP-EGFP under the control of Scer\GAL4sr-md710.

      (Wayburn and Volk, 2009)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      LrtUAS.EGFP/Scer\GAL4sr-md710 rescues Df(2R)BSC403

      (Wayburn and Volk, 2009)
      Comments

      Expression of LrtScer\UAS.T:Avic\GFP-EGFP under the control of Scer\GAL4sr-md710 rescues the muscle defects seen in Df(2R)BSC403 homozygous embryos.

      (Wayburn and Volk, 2009)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      LrtScer\UAS.T:Avic\GFP-EGFP
      LrtUAS.EGFP
      Name Synonyms
      Secondary FlyBase IDs
        References (1)