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General Information
Symbol
Dmel\P{GawB}srmd710
Species
D. melanogaster
Name
FlyBase ID
FBti0017047
Also Known As
Stripe-Gal4, sr-GAL4, srGAL4, sr.Gal4
Description
Inserted Element
Uses

GAL4 reporter/driver

Affected gene(s)
Viability / fertility
Associated allele(s)
Stock availability
LINE ID
Genomic Location
Chromosomal Location
3R ( 90F1 )
Sequence Location
3R:18,121,952..18,121,952 [+]
Target / Docking site
Member of Large Scale Dataset(s)
Dataset
Description
Detailed Mapping Data
Chromosome (arm)
Sequence Location
3R:18,121,952..18,121,952 [+]
Orientation
Cytological location (computed by FlyBase)
90F1 (inferred by FlyBase from sequence location)
Cytological location (reported)
Insertion into Natural transposon
Comments concerning location
Sequence Data
Flanking sequence
Inserted Element
Construct
Location-dependent role
Size (Kb)

11.279

Associated alleles
Molecular map
Affected Gene(s)
Alleles and Phenotypes
Expression Data
Reporter Expression
distribution deduced from reporter
Stage
Tissue/Position (including subcellular localization)
Reference
distribution deduced from reporter (Gal4 UAS)
Stage
Tissue/Position (including subcellular localization)
Reference
Additional Information
Statement
Reference

To study tendon development, sr reporter expression was studied during leg development relative to and odd reporter, which is expressed at the segmental joints. The first tendon to develop is the long tendon of the tarsi that arises from cells coexpressing sr and odd at the T5/pretarsus boundary at early third instar. These cells invaginate and elongate into the tarsal cavity formed by the progressive evagination of the leg disc at the beginning of metamorphosis. By the end of leg development, they will form a long internal tube extending from pre-tarsus to femur with the apical pole facing the lumen. With a short delay, another cluster of tendon precursor cells is specified during the third instar at the femur/tibia boundary in the dorsal position. Subsequently, during early pupation, additional sr-positive clusters are specified along the five segmental pre-patterned odd-positive boundary rings. This indicates that odd/sr-positive tendon precursors are specified progressively following the leg proximodistal segmentation with odd expression preceding sr expression. N was observed to appear sequentially and precede sr expression.

Drives expression in tendon cells.

Expression is the same as that observed for the sr gene, and does not overlap with the expression pattern of ac or sc.

Larval expression is observed in tendon cells.

Pupal expression is observed in the attachment sites of the anterior dorsal medial muscles.

 
Data on Genetic Line
Line ID
Origin as a multiple insertion line
Progenitor(s) within the Genome
Related Aberration or Balancer
Aberration
Balancer
Stocks (1)
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (18)
References (45)