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General Information
Symbol
Dmel\shotLA-Δrod1.UAS.GFP
Species
D. melanogaster
Name
FlyBase ID
FBal0137091
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

Deletion of sequences encoding shot amino acids 1205 to 4599 (coordinates according to accession number AAF24343). This removes approximately 75% of the central domain, including all the spectrin repeats.

Allele components
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Expression of shotLA-Δrod1.Scer\UAS.T:Avic\GFP in embryonic motorneurons or tendon cells in a wild-type background does not engender any obvious dominant negative effects.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments

Expression of shotLA-Δrod1.Scer\UAS.T:Avic\GFP under the control of Scer\GAL4elav.PU rescues the increase in bouton number seen at the neuromuscular junction in shot3/shotVV third instar larvae.

Dendrites extend normally in shotunspecified mutant embryos expressing shotLA-Δrod1.Scer\UAS.T:Avic\GFP in motorneurons, but they appear less branched compared to wild-type.

Scer\GAL4sr-md710 driven expression of shotLA-Δrod1.Scer\UAS.T:Avic\GFP prevents muscle detachment in shotunspecified mutants, but 75% of tendon cells are abnormally elongated.

Expression of shotLA-Δrod1.Scer\UAS.T:Avic\GFP under the control of Scer\GAL41407 rescues the motor and sensory axon extension defects seen in shot3 mutants.

Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
shotLA-Δrod1.Scer\UAS.T:Avic\GFP
shotLA-Δrod1.UAS.GFP
Name Synonyms
Secondary FlyBase IDs
    References (4)